ABSTRACT
OBJECTIVE: To describe the sequelae one month after hospital discharge in patients who required admission to Intensive Care for severe COVID 19 pneumonia and to analyze the differences between those who received therapy exclusively with high-flow oxygen therapy compared to those who required invasive mechanical ventilation. DESIGN: Cohort, prospective and observational study. SETTING: Post-intensive care multidisciplinary program. PATIENTS OR PARTICIPANTS: Patients who survived admission to the intensive care unit (ICU) for severe COVID 19 pneumonia from April 2020 to October 2021. INTERVENTIONS: Inclusion in the post-ICU multidisciplinary program. MAIN VARIABLES OF INTEREST: Motor, sensory, psychological/psychiatric, respiratory and nutritional sequelae after hospital admission. RESULTS: 104 patients were included. 48 patients received high-flow nasal oxygen therapy (ONAF) and 56 invasive mechanical ventilation (IMV). The main sequelae found were distal neuropathy (33.9% IMV vs 10.4% ONAF); brachial plexopathy (10.7% IMV vs 0% ONAF); decrease in grip strength: right hand 20.67kg (±8.27) in VMI vs 31.8kg (±11.59) in ONAF and left hand 19.39kg (±8.45) in VMI vs 30.26kg (±12.74) in ONAF; and limited muscle balance in the lower limbs (28.6% VMI vs 8.6% ONAF). The differences observed between both groups did not reach statistical significance in the multivariable study. CONCLUSIONS: The results obtained after the multivariate study suggest that there are no differences in the perceived physical sequelae one month after hospital discharge depending on the respiratory therapy used, whether it was high-flow nasal oxygen therapy or prolonged mechanical ventilation, although more studies are needed to be able to draw conclusions.
Subject(s)
COVID-19 , Humans , COVID-19/complications , COVID-19/therapy , Patient Discharge , SARS-CoV-2 , Prospective Studies , Respiration, Artificial , Critical Care , Oxygen , HospitalsABSTRACT
Objective: To describe the sequelae one month after hospital discharge in patients who required admission to intensive care for severe COVID-19 pneumonia and to analyze the differences between those who received therapy exclusively with high-flow oxygen therapy compared to those who required invasive mechanical ventilation. Design: Cohort, prospective and observational study. Setting: Post-intensive care multidisciplinary program. Patients or participants: Patients who survived admission to the intensive care unit (ICU) for severe COVID-19 pneumonia from April 2020 to October 2021. Interventions: Inclusion in the post-ICU multidisciplinary program. Main variables of interest: Motor, sensory, psychological/psychiatric, respiratory and nutritional sequelae after hospital admission. Results: One hundred and four patients were included. 48 patients received high-flow nasal oxygen therapy (ONAF) and 56 invasive mechanical ventilation (IMV). The main sequelae found were distal neuropathy (33.9% IMV vs. 10.4% ONAF); brachial plexopathy (10.7% IMV vs. 0% ONAF); decrease in grip strength: right hand 20.67 kg (± 8.27) in VMI vs. 31.8 kg (± 11.59) in ONAF and left hand 19.39 kg (± 8.45) in VMI vs. 30.26 kg (± 12.74) in ONAF; and limited muscle balance in the lower limbs (28.6% VMI vs. 8.6% ONAF). The differences observed between both groups did not reach statistical significance in the multivariable study. Conclusions: The results obtained after the multivariate study suggest that there are no differences in the perceived physical sequelae one month after hospital discharge depending on the respiratory therapy used, whether it was high-flow nasal oxygen therapy or prolonged mechanical ventilation, although more studies are needed to be able to draw conclusions.
Subject(s)
Humans , Male , Female , Adolescent , Smoking Prevention , Smoke-Free Policy , Jurisprudence , Underage Drinking , Tobacco Products , Spain , Tobacco UseABSTRACT
No disponible
Subject(s)
Humans , Animals , Lung Diseases, Interstitial/diagnosis , Pulmonary Fibrosis/diagnosis , Biomarkers/analysis , Matrix Metalloproteinase 7 , Superoxide Dismutase , Oxidative Stress , Advanced Oxidation Protein Products , Biomarkers/bloodABSTRACT
No disponible
Subject(s)
Humans , Tobacco Use Disorder/therapy , Smoking Cessation/methods , Mobile Applications , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Smoking/epidemiology , Smoking/prevention & control , Tobacco Use Disorder/classification , Tobacco Use Disorder/epidemiology , Nicotine/adverse effects , Smoking Cessation/methods , Smoking Cessation/psychology , Tobacco Use Cessation/psychology , Varenicline/therapeutic use , Tobacco Use Cessation Devices/trendsABSTRACT
Las estenosis de arterias pulmonares es una causa de hipertensión pulmonar y se asocia generalmente a malformaciones cardíacas congénitas. Se diagnostican habitualmente en las primeras etapas de la vida. Puede estar provocado por el síndrome de rubeola congénita, dentro de la clásica triada compuesta por cataratas, hipoacusia y malformaciones cardiovasculares. Presentamos un adulto, asintomático durante la infancia, que comienza con disnea progresiva, detectándose múltiples estenosis en el árbol vascular pulmonar secundario a infección por el virus de la rubeola durante la gestación que fue tratado con angioplastia (dilatación con balón)
Stenosis of the pulmonary arteries is a cause of pulmonary hypertension and is generally associated with congenital car-diac malformations. It is usually diagnosed during the initial states of life. It may be caused by congenital rubella syndro-me, within a classic triad that includes cataracts, deafness and cardiovascular malformations. We present the case of an adult who was asymptomatic during childhood. The patient began having progressive dyspnea; multiple stenosis of the pulmo-nary artery tree was detected, secondary to a rubella viral in-fection during pregnancy. The stenosis was treated with angio-plasty (dilatation with balloon)
