ABSTRACT
La terapia fotodinámica se basa en la interacción de un agente fotosensibilizante que cuando es estimulado por la longitud de onda apropiada inducela formación de radicales libres que causan necrosis celular. Es una de las técnicas más recientes empleada en el tratamiento de algunos tipos de cáncer,aunque actualmente ya se ha demostrado su eficacia en otras enfermedades inflamatorias. En dermatología su principal indicación es el carcinomabasocelular, pero también se ha empleado en carcinoma escamoso in situ enfermedad de Bowen y más recientemente en acné, rosácea, varices,fotorejuvenecimiento, liquen, liquen escleroso y atrófico y leshmaniasis, entre otras dermatosis1
Photodynamic therapy is based in the interaction of a photoactive agent that when is properly stimulated by a specific wavelength it induces free radi-cals that lead to cellular necrosis. This is one of the newest treatments for some types of cancer and other inflammatory diseases. In dermatology, pho-todynamic therapy is used for malignant neoplasias such as basal cell carcinoma, Bowen disease in situ squamous cell carcinoma and morerecently it has been applied to inflammatory skin diseases such as acne, rosacea, lichen plannus, lichen sclerosus et atrophicus, and other conditions leishmaniasis, photodamaged skin, telagiectasias1
Subject(s)
Humans , Photochemotherapy/methods , Skin Diseases/therapy , Surveys and Questionnaires , Skin Neoplasms/therapy , Skin Aging , Levulinic Acids/therapeutic useABSTRACT
BACKGROUND: Long-lasting hypopigmentation induced by laser hair removal systems has been reported. OBJECTIVE. : To evaluate clinical aspects of a female Caucasian that developed long-lasting hypopigmentation in the arms and forearms after photodepilation with a long-pulsed alexandrite laser. METHOD: A 29-year-old Caucasian female (phototype III) with localized hypertrichosis in the upper limbs was submitted to long-pulsed alexandrite laser-assisted hair removal. One treatment session was done with these laser parameters: a pulse width of 2 ms, a spot of 7 mm, and fluence energy of 18 J/cm2. RESULTS: The patient developed long-lasting hypopigmentation (more than 6 months) in the arms and forearms after a single treatment session of photodepilation. CONCLUSION: Long-pulsed alexandrite laser may induce reversible melanocyte suppression and long-lasting hypopigmentation.
Subject(s)
Hair Removal/adverse effects , Hypopigmentation/etiology , Adult , Arm , Female , Hair Removal/methods , HumansABSTRACT
El laser SPTL-1 es un laser colorante pulsado creado específicamente para el tratamiento por fototermolisis selectiva de lesiones vasculares superficiales, como angiomas planos y telangioectasias faciales. Con este laser es posible el tratamiento en edades tempranas, al eliminar el riesgo de quemaduras y cicatrices hipertróficas, relativamente frecuentes con los láseres de argón y CO2
