Online Optimization Method for Nonlinear Model-Predictive Control in Angular Tracking for MEMS Micromirror.

In this brief, a precise angular tracking control strategy using nonlinear predictive optimization control (POC) approach is address. In order to deal with the model uncertainty and noise interference, a online Hammerstein-model-based POC is designed using online estimated parameters and model residual. Above all, a rate-dependent Duhem model is used to describe the nonlinear sub-model of the whole Hammerstein architecture for depicting multi-valued mapping nonlinear characteristic. Then, predictive output of angular deflection is obtained by Diophantine function based on linear submodel. Subsequently, the iterative control value depends on estimated parameters through data-driven is acquired. Later, based on the cost function, the iteratively optimization control quantity is fed back to the electromagnetic driven deflection micromirror (EDDM) system on the basis of Hammerstein architecture. It should be stressed that the control value is determined by real-time update model residual and defined cost function. Moreover, the stability of POC strategy is proposed. In addition, experimental result is proposed to validate the effectiveness of the control technique adopted in this paper.

Disseminated Trichosporon asahii infection presenting as eosinophilia in an immunocompetent patient: A case report.

Trichosporon are naturally found in external environments and are a part of the normal flora of the human skin, respiratory tract, and gastrointestinal tract. Disseminated Trichosporon infection occurs sporadically in patients with immunodeficiency, and is mainly manifested as blood, urine, catheter, and thorax/peritoneum infections, rarely as lymphatic, liver and spleen infections. Elevated blood eosinophil granulocyte from Trichosporon infection have rarely been reported. Here, we report a rare Case of eosinophilia associated with lymphatic and liver and spleen infections due to Trichosporon asahii in an immunocompetent patient. No reports of eosinophilia from Trichosporon infections other than lung, to our knowledge, have been published.

Species Distribution And Antibiotic Susceptibility Of Nocardia Isolates From Yantai, China.

PURPOSE: This study aimed to investigate the species distributions and drug sensitivities among 19 strains of Nocardia isolated from Yantai, China, from 2017 to 2019. PATIENTS AND METHODS: Definitive species identification was performed by sequencing a fragment of the 16S rRNA gene (1480 bp) and by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). The susceptibilities of the isolates to 15 commonly-used antibiotics were tested using the microbroth dilution method. RESULTS: Among the 19 Nocardia isolates, five species were confirmed. Seventeen of the 19 Nocardia spp. strains were identified consistently by the two methods, while two isolates of N. cyriacigeorgica were misidentified as N. otitidiscaviarum by MALDI-TOF MS. N. farcinica was the most common species (8/19), followed by N. cyriacigeorgica (6/19), N. otitidiscaviarum (2/19), N. brasiliensis (2/19), and N. nova (1/19). All isolates were susceptible to trimethoprim-sulfamethoxazole and amikacin, followed by linezolid and tigecycline (94.7% susceptibility rates). The sensitivity and minimum inhibitory concentration patterns for ciprofloxacin, moxifloxacin, clarithromycin, and tobramycin were significantly correlated with the species. CONCLUSION: These results regarding the distribution and antibiotic resistance features of Nocardia species further our understanding of the diversity of Nocardia species circulating in Yantai, China, and thus support the use of more accurate empirical treatments.

Associations between polymorphisms of the ADIPOQ gene and hypertension risk: a systematic and meta-analysis.

ADIPOQ gene polymorphisms have been indicated to be associated with hypertension; however, published studies have reported inconsistent results. Eligible studies were retrieved by searching the PubMed, Embase and China National Knowledge Infrastructure databases. The case group consisted of patients with hypertension, and the control group consisted of subjects with normal blood pressure. Based on eleven published articles, involving 4837 cases and 5618 controls, the pooled results from rs2241766 polymorphism showed increased risk in the allelic model (G VS T: OR = 1.16, 95%CI = 1.06-1.27), recessive model (GG VS GT + TT: OR = 1.34, 95%CI = 1.10-1.63), dominant model (GG + GT VS TT: OR = 1.15, 95%CI = 1.02-1.30) and homozygote model (GG VS TT: OR = 1.38, 95%CI = 1.21-1.69). In addition, rs266729 polymorphism showed increased risk for hypertension in the recessive model (GG VS GC + CC: OR = 1.43, 95%CI = 1.02-2.01). In the Caucasian subgroup, rs1501299 polymorphism showed decreased risk of hypertension in the allelic model (T VS G: OR = 0.75, 95%CI = 0.58-0.97), dominant model (TT + TG VS GG: OR = 0.83, 95%CI = 0.71-0.98) and heterozygote model (TG VS GG: OR = 0.82, 95%CI = 0.68-0.99). The rs2241766 polymorphism was associated with a significant increase in hypertension risk based on our analysis. Moreover, an increased risk of rs266729 in hypertension patients was also detected. Our meta-analysis suggests that the rs1501299 polymorphism may play a protective role in hypertension in Caucasian subgroup; however, this finding requires further study.