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9.
Malar J ; 16(1): 365, 2017 09 11.
Article in English | MEDLINE | ID: mdl-28893258

ABSTRACT

BACKGROUND: Malaria remains a major source of morbi-mortality among travellers. In 2007, a consensual multicenter Primary Care-Hospital shared guideline on travel-prior chemoprophylaxis, diagnosis and clinical management of imported malaria was set up in the Barcelona North Metropolitan area. The aim of the study is to assess the evolution of malaria cases in the area as well as its clinical management over the 10 years of its implementation. RESULTS: A total of 190 malaria cases, all them imported, have been recorded. The overall estimated malaria crude incidence was of 0.47 cases per 10,000 population/year (95% CI 0.34-0.59) with a slight significant positive slope especially at the expense of an increase in Indian sub-continent Plasmodium vivax cases. The number of patients who attended the pre-travel consultation was low (13.7%) as well as those with prescribed chemoprophylaxis (10%). Severe malaria was diagnosed in 34 (17.9%) patients and ICU admittance was required in 2.6% of them. Organ sequelae (two renal failures and one post-acute distress respiratory syndrome) were recorded in 3 patients at hospital discharge, although all three were recovered at 30 days. None of the patients died. Patients complying with severity criteria were significantly males (p = 0.04), came from Africa (p = 0.02), were mainly non-immigrant travellers (p = 0.01) and were attended in a hospital setting (p < 0.001). The most frequently identified species was Plasmodium falciparum (64.2%), P. vivax (23.2%), Plasmodium malariae (1.6%) and Plasmodium ovale (1.1%). Those patients diagnosed with P. falciparum malaria came more often from sub-Saharan Africa (p < 0.001) and those with P. vivax came largely from the Indian sub-continent (p = 0.003). Among the 126 patients in whom an immunochromatographic antigenic test was performed, the result was interpreted as falsely negative in 12.1% of them. False negative results can be related to cases with <1% parasitaemia. CONCLUSIONS: After 10 years of surveillance, a moderate increase in malaria incidence was observed, mostly P. vivax cases imported from the Indian sub-continent. Although severe malaria cases have been frequently reported, none of the patients died and organ sequelae were rare. Conceivably, the participation of the Primary Care and the District and Third Level Hospital professionals defining surveillance, diagnostic tests, referral criteria and clinical management can be considered a useful tool to minimize malaria morbi-mortality.


Subject(s)
Antimalarials/therapeutic use , Malaria/drug therapy , Malaria/epidemiology , Adolescent , Adult , Female , Guidelines as Topic , Humans , Incidence , Malaria/diagnosis , Male , Middle Aged , Spain/epidemiology , Travel , Young Adult
10.
Med. clín (Ed. impr.) ; 149(4): 170-175, ago. 2017. tab, graf
Article in Spanish | IBECS | ID: ibc-165588

ABSTRACT

Debemos reconocer el error diagnóstico como un episodio adverso posible e inherente al acto clínico, e incorporarlo con normalidad al resto de los indicadores de calidad asistencial. Por diferentes fuentes de información podemos conocer su frecuencia, aunque probablemente todavía está subestimada. En contra de lo que se podría suponer, en la mayoría de los casos no acontece en enfermedades infrecuentes. Sus causas suelen ser complejas y multifactoriales, con aspectos tanto cognitivos individuales como del sistema. Estos errores pueden tener un gran impacto clínico y socioeconómico. Es necesario aprender de los errores diagnósticos para desarrollar un sistema seguro, propio de una cultura de calidad (AU)


Diagnostic errors have to be recognised as a possible adverse event inherent to clinical activity and incorporate them as another quality indicator. Different sources of information report their frequency, although they may still be underestimated. Contrary to what one could expect, in most cases, it does not occur in infrequent diseases. Causes can be complex and multifactorial, with individual cognitive aspects, as well as the health system. These errors can have an important clinical and socioeconomic impact. It is necessary to learn from diagnostic errors in order to develop an accurate and reliable system with a high standard of quality (AU)


Subject(s)
Humans , Diagnostic Errors/statistics & numerical data , Emergency Treatment/statistics & numerical data , Safety Management/trends , Emergency Service, Hospital/statistics & numerical data , Risk Factors
11.
Med Clin (Barc) ; 149(4): 170-175, 2017 Aug 22.
Article in English, Spanish | MEDLINE | ID: mdl-28571967

ABSTRACT

Diagnostic errors have to be recognised as a possible adverse event inherent to clinical activity and incorporate them as another quality indicator. Different sources of information report their frequency, although they may still be underestimated. Contrary to what one could expect, in most cases, it does not occur in infrequent diseases. Causes can be complex and multifactorial, with individual cognitive aspects, as well as the health system. These errors can have an important clinical and socioeconomic impact. It is necessary to learn from diagnostic errors in order to develop an accurate and reliable system with a high standard of quality.


Subject(s)
Diagnostic Errors , Emergency Service, Hospital , Diagnostic Errors/adverse effects , Diagnostic Errors/prevention & control , Diagnostic Errors/psychology , Diagnostic Errors/statistics & numerical data , Humans , Quality Improvement , Quality Indicators, Health Care
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