ABSTRACT
Russell bodies are accumulations of immunoglobulins within hyperstimulated plasma cells of the intestinal mucosa associated with chronic inflammation of benign progression, but may be confused with lymphoplasmacytic lymphoma, MALT lymphoma, multiple myeloma, or "signet-ring" cells, among others. There are few cases of gastric involvement, but duodenal involvement is even rarer with less than 10 published cases. Endoscopic examination with quality biopsies and anatomopathologic analysis with immunohistochemistry are essential to make an adequate differential diagnosis with other more severe processes. In any case, the treatment is that of the underlying disease.
ABSTRACT
Esophageal, gastric and duodenal ulcers are found in immunocompromised patients due to virus, mainly cytomegalovirus (CMV), and less frequently Epstein-Barr virus (EBV), varicella zoster virus (VZV) and herpes simplex virus (HSV) type 1 or 2.
Subject(s)
Epstein-Barr Virus Infections , Herpesvirus 1, Human , Stomach Ulcer , Cytomegalovirus , Epstein-Barr Virus Infections/complications , Herpesvirus 4, Human , HumansABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Dasatinib/adverse effects , Antineoplastic Agents/adverse effects , Colitis/immunology , Colitis/diagnostic imaging , Antineoplastic Agents, Immunological/adverse effects , Cytomegalovirus Infections/diagnostic imaging , Antineoplastic Agents/therapeutic use , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy , Colitis/virology , ColonoscopyABSTRACT
The effects of immunotherapy are numerous and are still being discovered. We present a case report of a patient who received dasatinib for chronic myeloid leukemia. A colonoscopy was performed due to a positive fecal occult blood test and colitis was observed. Furthermore, she also had a cytomegalovirus infection. This case highlights the importance to detect cases of immunomodulatory drugs induced colitis by the fecal occult blood test.
Subject(s)
Colitis , Leukemia, Myelogenous, Chronic, BCR-ABL Positive , Colitis/chemically induced , Dasatinib/adverse effects , Female , Humans , Immunotherapy , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy , Occult BloodABSTRACT
No disponible
