Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review.

Hepatitis C virus still represents a major cause of morbidity and mortality worldwide. In Peru, two national practice guidelines for the management of this infection were published more than 5 years ago; however, the latest breakthroughs in the treatment make it necessary to update these guidelines. We reviewed the most recent recommendations of the international guidelines and compared them with the current Peruvian guidelines. We found major differences, such as the use of Glecaprevir/Pibrentasvir as a first-line therapy, which is contemplated in the World Health Organization guideline, and recommended by American and European guidelines, but is not considered in the Peruvian guidelines. Another crucial difference lies in the management of patients with chronic kidney disease, who are treated nowadays with a variety of direct-acting antivirals, with no restrictions on the use of Sofosbuvir-based regimens in first-world countries, an approach that has not been adopted in Peru. We believe that standardization of the recommendations of the Peruvian guidelines is imperative, including the new therapeutic strategies that have emerged in recent years. We also suggest conducting a cost effectiveness analysis in the Peruvian context to allow for the implementation of new antivirals, and to achieve a better control of hepatitis C in the country.

Health science students' preparedness for climate change: a scoping review on knowledge, attitudes, and practices.

INTRODUCTION: Climate change (CC) is a global public health issue, and the role of health professionals in addressing its impact is crucial. However, to what extent health professionals are prepared to deal with CC-related health problems is unclear. We aimed to evaluate the knowledge, attitudes, and practices of health students about the CC. METHODS: We conducted a scoping review through systematic searches in PubMed, Scopus, Web of Science, Proquest, and EBSCO. We included original scientific research with no language or time restrictions. Two authors independently reviewed and decided on the eligibility of the studies, then performed data extraction. RESULTS: 21 studies were included, with a total of 9205 undergraduate nursing, medical, pharmacy, and public health students mainly. Most health science students (> 75%) recognized human activities as the main cause of CC. However, they perceived a lack of knowledge on how to address CC. Moreover, we found inadequate coverage or limited development of CC in related curricula that may contribute to incomplete learning or low confidence in the theoretical and practical concepts of students. CONCLUSION: The findings of our scoping review suggest that while health sciences students possess a general understanding of CC, there is a significant gap in their knowledge regarding its specific health impacts. To address this gap, there is a need for targeted education and training for future health care professionals that emphasizes the health effects of CC.

Factors associated with the consumption of medicinal plants for the prevention of COVID-19 in peruvian population: a cross-sectional study. / Factores asociados con el consumo de plantas medicinales para la prevención de COVID-19 en población peruana: un estudio transversal.

OBJECTIVES.: Motivation for the study. No study conclusively recommends the use of medicinal plants to treat COVID-19 symptoms, and their indiscriminate use may present health risks. Main findings. Sixty percent of participants consumed medicinal plants to prevent COVID-19. This was particularly true for those living in the Peruvian highlands and individuals with family members diagnosed or deceased from COVID-19, who perceive a higher risk of infection and use medications or chlorine dioxide as preventive measures. Implications. Communication strategies emphasizing validated preventive practices and educating about the risks of consuming medicinal plants should be tailored to the predominant characteristics of the consumer. Determine the factors associated with the consumption of medicinal plants as a preventive measure against COVID-19 in the Peruvian population. MATERIALS AND METHODS.: A population over 18 years of age, living in Peru and without a history of COVID-19 disease, was evaluated. The factors associated with the consumption of medicinal plants were evaluated using a Poisson regression model with robust variances. RESULTS.: Of the 3231 participants included, 84.6% were young adults (18-29 years old), 62.7% were women, and 59.7% consumed a medicinal plant to prevent COVID-19 infection. The factors associated with the consumption of medicinal plants to prevent COVID-19 infection were residing in the Peruvian highlands, having had a family member diagnosed with COVID-19, having had a family member die from COVID-19, considering their family to be at increased risk of infection, having used medications or chlorine dioxide to prevent COVID-19, having medical information as the main source of information about COVID-19, thinking that medicinal plants are effective in preventing COVID-19 disease, or not being informed about their effectiveness. CONCLUSION.: Sixty percent of the participants reported having consumed a medicinal plant to prevent COVID-19. Authorities must apply communication strategies about the implications of consuming medicinal plants, prioritizing population groups with higher consumption patterns.

OBJETIVOS: Motivación para realizar el estudio. Ningún estudio recomienda de manera concluyente el uso de plantas medicinales para tratar los síntomas de la COVID-19, y su uso indiscriminado puede presentar riesgos para la salud. Principales hallazgos. El 60% de los participantes utilizó plantas medicinales para la prevención de la COVID-19. Especialmente aquellos de la sierra peruana y personas con familiares diagnosticados o fallecidos por COVID-19, que perciben mayores riesgos de contagio y utilizan medicamentos o dióxido de cloro como medidas preventivas. Implicancias. Las estrategias de comunicación esenciales para las prácticas preventivas validadas y la educación sobre los riesgos del consumo de plantas medicinales deben adaptarse a las características predominantes del consumidor. Determinar los factores asociados al consumo de plantas medicinales como prevención de la COVID-19 en la población peruana. MATERIALES Y MÉTODOS.: Se evaluó población mayor de 18 años, residentes en Perú y sin antecedentes de enfermedad por COVID-19. Los factores asociados al consumo de plantas medicinales se evaluaron mediante un modelo de regresión de Poisson con varianzas robustas. RESULTADOS.: De 3231 participantes incluidos, el 84,6% eran jóvenes (18-29 años), el 62,7% eran mujeres y el 59,7% consumía alguna planta medicinal para prevenir la COVID-19. Los factores asociados al consumo de plantas medicinales para prevenir el contagio de COVID-19 fueron residir en la sierra peruana, haber tenido un familiar diagnosticado con COVID-19, haber tenido un familiar fallecido por COVID-19, considerar que su familia se encuentra en mayor riesgo de infección, haber usado medicamentos o dióxido de cloro para prevenir la COVID-19, tener información médica como principal fuente de información sobre la COVID-19, pensar que las plantas medicinales son efectivas para prevenir la enfermedad COVID-19 o no estar informado sobre su eficacia. CONCLUSIÓN: . El 60% de los participantes reportó haber consumido alguna planta medicinal para prevenir la COVID-19. Es importante que las autoridades apliquen estrategias de comunicación sobre lo que implica el consumo de plantas medicinales, priorizando los grupos poblacionales que tienen mayores patrones de consumo.

Prevalence of computer vision syndrome: A systematic review and meta-analysis

Purpose This review aimed to estimate the prevalence of computer vision syndrome (CVS) in the general population and subgroups. Methods A search was conducted in the following the databases: PubMed, SCOPUS, EMBASE, and Web of Science until February 13, 2023. We included studies that assessed the prevalence of CVS in any population. The Joanna Briggs Institute's critical appraisal tool was used to evaluate the methodological quality. A meta-analysis of the prevalence of CVS was done using a random-effects model, assessing the sources of heterogeneity using subgroup and meta-regression analyses. Results A total of 103 cross-sectional studies with 66 577 participants were included. The prevalence of CVS was 69.0% (95% CI: 62.3 to 75.3; I2: 99.7%), ranging from 12.1 to 97.3% across studies. Point prevalence was higher in women than in men (71.4 vs. 61.8%), university students (76.1%), Africa (71.2%), Asia (69.9%), contact lens wearers (73.1% vs. 63.8%) in studies conducted before the COVID-19 pandemic (72.8%), and in those that did not use the CVS-Q questionnaire (75.4%). In meta-regression, using the CVS-Q scale was associated with a lower prevalence of CVS. Conclusion Seven out of ten people suffer from CVS. Preventive strategies and interventions are needed to decrease the prevalence of this condition which can affect productivity and quality of life. Future studies should standardize a definition of CVS. (AU)

Percutaneous coronary intervention versus optimal medical therapy for stable coronary artery disease: An umbrella review.

Background: Invasive management of stable coronary artery disease is still a controversial topic. The purpose of this umbrella review was to synthesize systematic reviews (SRs) that evaluate the benefits and harms of percutaneous coronary intervention (PCI) versus optimal medical therapy (OMT) in patients with stable coronary artery disease. Methods: We systematically searched PubMed/MEDLINE, Embase, and CENTRAL from 2018 to August 7, 2022. We included SRs with meta-analyses of randomized controlled trials (RCTs) that evaluated the question of interest. We assessed the methodological quality of the SRs with the AMSTAR-2 tool. We summarized the results of the outcomes for each SR. We calculated the degree of overlap of the RCTs included in the SRs using the corrected covered area (CCA). Results: We found 10 SRs with meta-analyses. The SRs included 3 to 15 RCTs. The degree of overlap among the SRs was very high (CCA > 15%). No SR evaluated the certainty of the evidence using the GRADE system and 9 out of 10 had critically low methodological quality. The SRs reported heterogeneous results for the outcomes of all-cause mortality, myocardial infarction, revascularization, and angina. On the other hand, for the outcomes of cardiovascular mortality and stroke, all SRs agreed that there were no differences between PCI and OMT alone. Conclusions: We found 10 SRs on the use of PCI compared to OMT alone for patients with stable coronary artery disease. However, none had high methodological quality, none evaluated the certainty of the evidence using the GRADE approach, and the results were inconsistent for several outcomes. This variability in evidence may result in divergent clinical decisions for the management of stable coronary artery disease among healthcare professionals. It is necessary to perform a high-quality SR using the GRADE approach to clarify the balance of benefits and harms of PCI.

Prevalence of computer vision syndrome: A systematic review and meta-analysis.

PURPOSE: This review aimed to estimate the prevalence of computer vision syndrome (CVS) in the general population and subgroups. METHODS: A search was conducted in the following the databases: PubMed, SCOPUS, EMBASE, and Web of Science until February 13, 2023. We included studies that assessed the prevalence of CVS in any population. The Joanna Briggs Institute's critical appraisal tool was used to evaluate the methodological quality. A meta-analysis of the prevalence of CVS was done using a random-effects model, assessing the sources of heterogeneity using subgroup and meta-regression analyses. RESULTS: A total of 103 cross-sectional studies with 66 577 participants were included. The prevalence of CVS was 69.0% (95% CI: 62.3 to 75.3; I2: 99.7%), ranging from 12.1 to 97.3% across studies. Point prevalence was higher in women than in men (71.4 vs. 61.8%), university students (76.1%), Africa (71.2%), Asia (69.9%), contact lens wearers (73.1% vs. 63.8%) in studies conducted before the COVID-19 pandemic (72.8%), and in those that did not use the CVS-Q questionnaire (75.4%). In meta-regression, using the CVS-Q scale was associated with a lower prevalence of CVS. CONCLUSION: Seven out of ten people suffer from CVS. Preventive strategies and interventions are needed to decrease the prevalence of this condition which can affect productivity and quality of life. Future studies should standardize a definition of CVS.

Factores asociados con el consumo de plantas medicinales para la prevención de COVID-19 en población peruana: un estudio transversal / Factors associated with the consumption of medicinal plants for the prevention of COVID-19 in peruvian population: a cross-sectional study

RESUMEN Objetivos . Determinar los factores asociados al consumo de plantas medicinales como prevención de la COVID-19 en la población peruana. Materiales y métodos. Se evaluó población mayor de 18 años, residentes en Perú y sin antecedentes de enfermedad por COVID-19. Los factores asociados al consumo de plantas medicinales se evaluaron mediante un modelo de regresión de Poisson con varianzas robustas. Resultados. De 3231 participantes incluidos, el 84,6% eran jóvenes (18-29 años), el 62,7% eran mujeres y el 59,7% consumía alguna planta medicinal para prevenir la COVID-19. Los factores asociados al consumo de plantas medicinales para prevenir el contagio de COVID-19 fueron residir en la sierra peruana, haber tenido un familiar diagnosticado con COVID-19, haber tenido un familiar fallecido por COVID-19, considerar que su familia se encuentra en mayor riesgo de infección, haber usado medicamentos o dióxido de cloro para prevenir la COVID-19, tener información médica como principal fuente de información sobre la COVID-19, pensar que las plantas medicinales son efectivas para prevenir la enfermedad COVID-19 o no estar informado sobre su eficacia. Conclusión . El 60% de los participantes reportó haber consumido alguna planta medicinal para prevenir la COVID-19. Es importante que las autoridades apliquen estrategias de comunicación sobre lo que implica el consumo de plantas medicinales, priorizando los grupos poblacionales que tienen mayores patrones de consumo.

ABSTRACT Objectives. Determine the factors associated with the consumption of medicinal plants as a preventive measure against COVID-19 in the Peruvian population. Materials and methods. A population over 18 years of age, living in Peru and without a history of COVID-19 disease, was evaluated. The factors associated with the consumption of medicinal plants were evaluated using a Poisson regression model with robust variances. Results. Of the 3231 participants included, 84.6% were young adults (18-29 years old), 62.7% were women, and 59.7% consumed a medicinal plant to prevent COVID-19 infection. The factors associated with the consumption of medicinal plants to prevent COVID-19 infection were residing in the Peruvian highlands, having had a family member diagnosed with COVID-19, having had a family member die from COVID-19, considering their family to be at increased risk of infection, having used medications or chlorine dioxide to prevent COVID-19, having medical information as the main source of information about COVID-19, thinking that medicinal plants are effective in preventing COVID-19 disease, or not being informed about their effectiveness. Conclusion. Sixty percent of the participants reported having consumed a medicinal plant to prevent COVID-19. Authorities must apply communication strategies about the implications of consuming medicinal plants, prioritizing population groups with higher consumption patterns.

Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis.

OBJECTIVE: The objective of this systematic review and meta-analysis was to assess the prevalence of hypertension in populations living at altitude in Latin America and the Caribbean. METHODS: We conducted a systematic search from January 1, 2000 to January 10, 2023 in Web of Science (WoS)/Core Collection, WoS/Medline, WoS/Scielo, Scopus, PubMed and Embase databases. We included studies that assessed the prevalence of hypertension in altitude populations (>1500 m.a.s.l.) and these were meta-analyzed using a random-effects model. To assess the sources of heterogeneity, we performed subgroup and meta-regression analyses. RESULTS: Thirty cross-sectional studies (117 406 participants) met the inclusion criteria. Studies used different cut-off points. The prevalence of hypertension in the studies that considered the cut-off point of ≥ 140/90 mmHg in the general population was 19.1%, ≥ 130/85 mmHg was 13.1%, and ≥ 130/80 mmHg was 43.4%. There was a tendency for the prevalence of hypertension to be higher in men. In meta-regression analyses, no association was found between altitude, mean age, year of publication, risk of bias and prevalence of hypertension. CONCLUSION: The prevalence of hypertension in the altitude population of Latin America and the Caribbean is lower than that reported in populations living at sea level and lower than other altitude populations such as Tibetans. PROSPERO: CRD42021275229.

Trastornos musculoesqueléticos y prácticas ergonómicas en universitarios peruanos durante la pandemia de la COVID-19

Introducción: El aislamiento social impuesto por la pandemia de la COVID-19 ha obligado a adaptarse a la educación a distancia. Objetivo: Determinar la prevalencia de trastornos musculoesqueléticos y su asociación con las prácticas ergonómicas durante el uso de la computadora en estudiantes de una universidad peruana. Métodos: Se realizó un estudio transversal en octubre de 2020. La muestra se compuso por 738 estudiantes, a quienes se les aplicaron el cuestionario nórdico estandarizado, para detectar síntomas de trastornos musculoesqueléticos, y otro desarrollado por los autores, para evaluar las prácticas ergonómicas. Resultados: La prevalencia de trastornos musculoesqueléticos fue de 97,4 %. Las regiones más afectadas resultaron el cuello (85,5 %), la región lumbar (73 %) y la dorsal (70,2 %). Los estudiantes con antecedentes de algún traumatismo (PRa: 1,03; IC 95 %: 1,01-1,04) que, durante el uso de la computadora, adoptaron las posturas decúbito prono (RPa: 1,02; IC 95 %: 1,01-1,04) y sentados con la cabeza inclinada (RPa: 1,03; IC 95 %: 1,00-1,07) tuvieron mayor prevalencia de un trastorno musculoesquelético. Conclusiones: Existe una alta prevalencia de trastornos musculoesqueléticos en los universitarios. Sobresalen el sexo femenino y quienes adoptan malas posturas durante el uso de la computadora; por tanto, se deben brindar medidas ergonómicas preventivas y de intervención en esta población.

Introduction: The social isolation imposed by the COVID-19 pandemic has made it necessary to adapt to distance education. Objective: To determine the prevalence of musculoskeletal disorders and their association with ergonomic practices during computer use in students from a Peruvian university. Methods: A cross-sectional study was carried out in October 2020. The sample consisted of 738 students, they had the standardized Nordic questionnaire to detect symptoms of musculoskeletal disorders; and another, developed by the authors, to evaluate ergonomic practices. Results: The prevalence of musculoskeletal disorders was 97.4%. The most affected regions were the neck (85.5%), the lumbar region (73%) and the dorsal region (70.2%). Students with history of trauma (PRa: 1.03; 95% CI: 1.01-1.04) who, while using the computer, adopted the prone position (RPa: 1.02; 95% CI : 1.01-1.04) and sitting with head tilted (RPa: 1.03; 95% CI: 1.00-1.07) had higher prevalence of a musculoskeletal disorder. Conclusions: There is high prevalence of musculoskeletal disorders in university students. The female sex and those who adopt incorrect postures while using the computer stand out; therefore, preventive and intervention ergonomic measures should be provided in this population.

Evaluating the Diagnostic Performance of Hemoglobin in the Diagnosis of Iron Deficiency Anemia in High-Altitude Populations: A Scoping Review.

We evaluated the available literature on the diagnostic performance of hemoglobin (Hb) in the diagnosis of iron deficiency anemia (IDA) in high-altitude populations. We searched PubMed, Web of Science, Scopus, Embase, Medline by Ovid, the Cochrane Library, and LILCAS until 3 May 2022. We included studies that evaluated the diagnostic performance (sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curves, and accuracy) of Hb (with and without an altitude correction factor) compared to any iron deficiency (ID) marker (e.g., ferritin, soluble transferrin receptor (sTFR), transferrin saturation, or total body iron (TBI)) in populations residing at altitudes (≥1000 m above sea level). We identified a total of 14 studies (with 4522 participants). We found disagreement in diagnostic performance test values between the studies, both in those comparing hemoglobin with and in those comparing hemoglobin without a correction factor for altitude. Sensitivity ranged from 7% to 100%, whereas specificity ranged from 30% to 100%. Three studies reported higher accuracy of uncorrected versus altitude-corrected hemoglobin. Similarly, two studies found that not correcting hemoglobin for altitude improved the receiver operating characteristic (ROC) curves for the diagnosis of iron deficiency anemia. Available studies on high-altitude populations suggest that the diagnostic accuracy of Hb is higher when altitude correction is not used. In addition, the high prevalence of anemia in altitude regions could be due to diagnostic misclassification.

Green space exposure and type 2 diabetes mellitus incidence: A systematic review.

INTRODUCTION: Epidemiological studies have suggested that exposure to green spaces is associated with a lower prevalence of diabetes. The aim of this systematic review was to summarize the evidence on green spaces and diabetes mellitus II (T2DM) in longitudinal studies. METHODS: We searched PubMed, SCOPUS, Web of Science (WoS)/Core Collection, WoS/MEDLINE, and EMBASE until February 2023. We included cohort studies that assessed the incidence of T2DM according to the level of exposure to green spaces. Two authors independently performed study selection, data extraction, and analysis of risk of bias. No meta-analysis was performed due to clinical heterogeneity between studies. RESULTS: We included 13 cohort studies with a sample size ranging from 1700 to 1 922 545 participants. Studies presented different ways of defining (quartiles, percentages) and measuring (tools, buffers) green spaces. Similarly, the definition of T2DM was heterogeneous (self-reports, medical records, clinical criteria). Twelve studies showed that individuals with higher exposure to green spaces had a decreased incidence of T2DM. Out of these 12 studies, 10 revealed statistically significant differences. All studies were of high methodological quality, except for one. CONCLUSION: Our findings suggest that exposure to green space could be a protective factor for the development of T2DM. Promoting policies to preserve and increase green space could help to reduce T2DM at the community level. More standardization of green space exposure definition is needed in studies on green space and T2DM.

Association between self-reported evidence-based medicine competencies and prescribing of drugs without scientific evidence against mild COVID-19 among recently graduated physicians in Peru.

Objective: To evaluate the association between self-rated evidence-based medicine (EBM) competencies and the prescription of drugs without scientific evidence against mild COVID-19 (present with any of the signs and symptoms of COVID-19 but who do not have shortness of breath, dyspnea, or abnormal chest imaging) among recently graduated physicians in Peru. Methods: We conducted an analytical cross-sectional study where we evaluated a non-probability sample of recently graduated physicians during June and July 2021 (end of second wave of COVID-19 in Peru). Self-rated EBM competencies were assessed by four domains (formulation of a clinical question, search, analysis, and application) using a Likert scale with scores from zero to four ("Very inadequate" = 0, to "Very Adequate" = 4), it was considered as "Adequate" if the score was three or four. In addition, the variable "General competence on EBM" was rated as "Adequate" if in all domains evaluated it presented an adequate self-rating. For the outcome, drug prescription, we considered the use of ivermectin, azithromycin, other antibiotics, hydroxychloroquine, dexamethasone, and anticoagulants (drugs with no efficacy demonstrated for patients with mild COVID-19). To assess the association, we used Poisson regression models with robust variances and obtaining crude (cPR) and adjusted (aPR) prevalence ratios with their 95% confidence intervals (95%CI). Results: Of a total of 239 physicians included 70.7% prescribed at least one drug without scientific evidence. A total of 51.1% reported adequate ratings in all evaluated domains of EBM. Self-rating the "Clinical Question Formulation" competency as adequate was associated with a lower frequency of prescribing medications for mild COVID-19 (aPR: 0.93; 95% CI: 0.91-0.95). While self-rating as adequate the competency of "Identify possible implications of investigations" was associated with an increase in the prescription of such drugs (aPR: 1.14; 95% CI: 1.09-1.20). Additionally, self-rating all domains as adequate were associated with less prescription (aPR: 0.93; 95% CI: 0.90-0.96). Conclusion: Seven out of ten recently graduated physicians prescribed some type of medication without scientific evidence to treat patients with mild COVID-19. Having adequate self-perceived EBM competencies was associated with a lower frequency of prescribing medications without scientific evidence to manage patients with mild COVID-19.

Level of Knowledge Regarding Mpox among Peruvian Physicians during the 2022 Outbreak: A Cross-Sectional Study.

Introduction: Due to the high incidence of mpox in Peru and the poor knowledge about this disease among healthcare workers in non-endemic countries, it is crucial to determine the knowledge status of Peruvian physicians. Methodology: We conducted an analytical cross-sectional study based on an online survey from August to September 2022. Physicians who had a medical license and lived and practiced medicine in Peru were included. To evaluate the factors associated with a higher level of knowledge, we used crude (cPR) and adjusted (aPR) prevalence ratios with 95% confidence intervals (95% CI) using Poisson regression. Results: We included 463 physicians. The mean age was 36.6 (SD: 10.3) years, and most were male (58.1%). Regarding knowledge, the median knowledge score was 14 [IQR: 13 to 15] out of 17 points. In terms of knowledge gaps, only 60.7% of the participants knew that there was an FDA-approved vaccine for mpox, 49.0% of participants knew about mpox proctitis and 33.3% acknowledged that it could be transmitted by the bite of an infected rodent. We found that taking care of patients with mpox (aPR: 1.39; 95% CI: 1.13 to 1.72) was associated with higher knowledge (>p50), while living in the eastern macro-region (aPR: 0.62; 95% CI: 0.42 to 0.93) was associated with lower knowledge (≤p50). Conclusions: Our study showed a high level of knowledge about mpox among Peruvian physicians. However, educational campaigns may be necessary, especially for physicians from the eastern region and those who do not have clinical experience with mpox.

[Environmental health: an educational need for Peruvian physicians] / Salud ambiental: una necesidad educativa para los médicos del Perú.

Introduction: The implementation of courses related to environmental health in undergraduate curricula favors the formation of physicians more committed to the impact of climate change on health. The aim of the study was to identify the prevalence of environmental health courses in Peruvian medical schools, as well as their comparison with air quality levels for each region of the country.Methods: A descriptive study was carried out. We searched the web page of the National Superintendence of University Higher Education (SUNEDU) of Peru and selected those universities with registered human medicine faculties. We analyzed whether they included in their curriculum a course related to environmental medicine and compared it with the levels of air quality (particulate matter) for each region. Results: Of 41 medical schools included, 26 (63.4%) of them included a course related to environmental health in their curriculum, and 2 (7.7%) of them included it as an optional course. Of the regions with a moderate/bad air quality index, 63% have medical schools with lecture courses on environmental medicine. Conclusions: It is necessary to standardize the methodology, contents and teaching resources, as well as the study of relevant topics such as climate change, in addition to its integration with the other courses of the medical career given the importance of environmental health in the different regions of Peru

Introducción: La implementación de cursos relacionados a la salud ambiental en las currículas de pregrado favorece la formación de médicos más comprometidos con el impacto del cambio climático sobre la salud. El objetivo del estudio fue identificar la prevalencia de cursos lectivos sobre salud ambiental en facultades de medicina del Perú, así como su comparación con los niveles de calidad de aire por cada región del país. Métodos: Se realizó un estudio descriptivo. Se buscó en la página web de la Superintendencia Nacional de Educación Superior Universitaria (SUNEDU) del Perú y se seleccionó aquellas universidades con facultad de medicina humana registradas. Se analizó si estas incluían en su currículo un curso relacionado a medicina ambiental y se comparó con los niveles de calidad de aire (Material particulado) por cada región. Resultados: De 41 facultades de medicina incluidas, 26 (63,4%) de ellas incluyeron en su currículum un curso relacionado a salud ambiental, y 2 (7,7%) de ellas lo incluyeron como un curso opcional. De las regiones con un índice de calidad de aire moderado/malo, el 63% cuentan con facultades de medicina con cursos lectivos sobre medicina ambiental. Conclusiones: Es necesario estandarizar su metodología, contenidos y recursos de enseñanza, así como el estudio de temas relevantes como el cambio climático, además de su integración con los demás cursos de la carrera médica dada la importancia que cobra la salud ambiental en las diferentes regiones del Perú.

Satisfacción del personal de salud y pacientes sobre un servicio de telesalud de un hospital de Perú / Satisfaction of healthcare workers and patients regarding telehealth service in a hospital in Peru

Objetivos. Evaluar el nivel de satisfacción con el servicio de telesalud del Hospital III Regional Honorio Delgado (HRHD) por parte del personal de salud y los pacientes atendidos, así como el nivel de madurez de implementación de dicho servicio. Materiales y métodos. Estudio observacional transversal llevado a cabo desde octubre a diciembre del 2021. La satisfacción del personal de salud y de los pacientes fueron evaluadas con la encuesta de Glaser et al. y el cuestionario Telemedicine Satisfaction Questionnaire (TSQ), respectivamente. El nivel de madurez del servicio se evaluó mediante la herramienta de medición del nivel de madurez de las instituciones de salud para implementar servicios de telemedicina de la Organización Panamericana de la Salud. Resultados. Se obtuvieron 129 respuestas del personal de salud. El número de profesionales no médicos satisfechos con el servicio de telesalud fue mayor al de médicos (72,5% vs 18,3%). De los 377 pacientes, el 77,6% manifestó estar satisfecho con el servicio. Con respecto al nivel de madurez, el servicio de telemedicina del HRHD cuenta con 32% de ítems en estado nulo, 40,8% en iniciado, 25,2% en avanzado y 2% en listo. Conclusiones. La satisfacción de los médicos fue menor a la de los otros profesionales de la salud. Los pacientes reportaron una satisfacción moderadamente alta. La implementación del servicio de telesalud en el HRHD se orienta hacia un nivel nulo o iniciado. Es importante que los tomadores de decisiones consideren la satisfacción de usuarios durante la implementación y seguimiento de los servicios de telesalud.

Objectives. To evaluate the level of satisfaction of healthcare workers and patients with the telehealth service of the Hospital III Regional Honorio Delgado (HRHD), as well as the maturity level of the telehealth service implementation. Materials and methods. Cross-sectional, observational study conducted from October to December 2021. The satisfaction of healthcare workers and patients was assessed with the Glaser et al. survey and the Telemedicine Satisfaction Questionnaire (TSQ), respectively. The level of service maturity was assessed using the Pan American Health Organization's instrument for measuring the maturity level of healthcare institutions implementing telemedicine service. Results. A total of 129 responses were obtained from healthcare workers. Non-physician professionals' satisfaction with the telehealth service was higher than that of physicians (72.5% vs. 18.3%). Of 377 patients, 77.6% stated they were satisfied with the service. Regarding the maturity level, the HRHD telemedicine service had 32% of items in null status, 40.8% in started, 25.2% in advanced, and 2% in ready conditions. Conclusions. Physician satisfaction was lower than that of other health professionals. Patients had a moderate-high satisfaction. The maturity level of telehealth implementation in HRHD was oriented towards a null or initiated level. Decision-makers need to consider user satisfaction for the telehealth implementation and the follow-up.

Factors Associated With Drug Consumption Without Scientific Evidence in Patients With Mild COVID-19 in Peru.

OBJECTIVE: This study aimed to evaluate the factors associated with the consumption of drugs without scientific evidence in patients with mild COVID-19 infection in Peru. METHODS: An analytical cross-sectional study was carried out including 372 adult patients with a history of mild COVID-19 disease. Factors associated with drug consumption were evaluated by Poisson regressions with robust variance adjustment using the bootstrapping resampling method. RESULTS: Seventy-two percent consumed some medication without scientific evidence, with antibiotics (71%) and ivermectin for human use (68%) being the most commonly used. Factors associated with the consumption of drugs to treat mild COVID-19 infection were thinking that the drugs are not effective (adjusted prevalence ratio, 0.55; 95% confidence interval, 0.41-0.74) and not being informed about the efficacy of the drugs (adjusted prevalence ratio, 0.48; 95% confidence interval, 0.36-0.65). CONCLUSIONS: Education of the population seems to be the main factor that increases the consumption of drugs without scientific evidence in the Peruvian population to treat mild COVID-19.

Adherence to Mediterranean diet associated with health-related quality of life in children and adolescents: a systematic review.

BACKGROUND: Health-related quality of life (HRQoL) has become a significant outcome in assessing interventions in the pediatric population and could be influenced by diet patterns. The Mediterranean diet (MD) pattern has been related to multiple positive health outcomes, including decreased cardiovascular risk and better mental health. We aimed to evaluate the association between MD adherence and HRQoL in children and adolescents. METHODS: The literature search was conducted in PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Ovid-MEDLINE databases from inception to May 2022. Two researchers independently checked titles and abstracts, evaluated full-text studies, extracted data, and appraised the risk of bias using the Newcastle-Ottawa Scale (NOS). RESULTS: Eleven studies (1 longitudinal and 10 cross-sectional), totaling 6,796 subjects, were included. Ten studies assessed MD adherence with KIDMED index, and one assessed MD adherence with Krece Plus test, while all included studies assessed HRQoL with a KIDSCREEN test. All studies analyzed the association between MD adherence and HRQoL with linear regression, and eight used adjusted models. Five studies found a significant positive association of MD adherence with HRQoL, with ß-values ranging from 0.13 to 0.26. Two found a nonsignificant positive relationship, while one found a negative association. According to the NOS criteria, the risk of bias assessment showed four studies with a low risk of bias and seven with a high risk of bias. CONCLUSION: Our findings suggest a positive correlation of MD adherence with HRQoL in children and adolescents. However, future research is needed to strengthen the evidence of this relationship. TRIAL REGISTRATION: CRD42021236188 (PROSPERO).

Recommendations for nutritional assessment across clinical practice guidelines: A scoping review.

BACKGROUND & AIMS: CPGs propose several methods and criteria to perform nutritional assessment, a key process to determine the type and severity of malnutrition, which generates variability in clinical practice and outcomes. The aim of the study was to describe the criteria considered by clinical practice guidelines (CPGs) for nutritional assessment. METHODS: We performed a scoping review systematically searching in PubMed, Trip Database, Google Scholar, and Google, until November 5, 2021. We included all CPGs mentioning tools or criteria for nutritional assessment in adults from the general population or with any specific pathology or condition. Two authors independently reviewed and decided on study selection and data extraction. RESULTS: We included 18 CPGs (12 elaborated in Europe). The CPGs recommended heterogeneous criteria for nutritional assessment: 16/18 CPGs included at least one body composition parameter (e.g., loss of muscle mass, loss of subcutaneous fat), 15/18 included history related to dietary intake, 15/18 included clinical history (e.g., weight loss), 10/18 included anthropometric measurement (e.g., low body mass index [BMI]), 11/18 included biochemical criteria (e.g., albumin, C-reactive protein), 8/18 included physical examination (e.g., fluid retention, sarcopenia, loss of subcutaneous fat), 8/18 included functional test (e.g., decreased handgrip strength), and 1/18 included catabolic state. Also, 9/18 CPGs mentioned a tool for nutritional assessment, the Subjective Global Assessment (SGA) the most common (8/18). None of the CPGs justified the inclusion of any of the tools or criteria they mentioned. CONCLUSIONS: The CPGs mentioned heterogeneous criteria for nutritional assessment. The most commonly mentioned criteria were decreased food intake, loss of muscle mass, weight loss, and low BMI. The most mentioned tool was the SGA. None of the CPGs provided a clear rationale for using certain criteria or tools for nutritional assessment.

Factors associated with prevention practices against COVID-19 in the Peruvian population: Disparities between rural and urban areas.

OBJECTIVE: To determine the factors associated with prevention practices against COVID-19 in the Peruvian population according to rural vs. urban locations. METHODS: Analytical cross-sectional study, secondary analysis based on a previously collected database. A sample of individuals over 18 years of age, residing in Peru and with no history of COVID-19was evaluated. Factors associated with prevention practices were evaluated using Poisson regressions with variance adjustment by region cluster and stratified by rurality. RESULTS: Of 3231 participants included, 2741 (84.8%) were from urban areas and 490 (15.2%) from rural areas. The frequency of good prevention practices against COVID-19 was 27.8% in our total sample. In urban areas the frequency of good prevention practices was 28.8% and in rural areas it was 22.5%. Factors associated with prevention practices against COVID-19 in both urban and rural areas were male sex (urban: aPR 0.64, 95%CI 0.55-0.75; rural: aPR 0.66, 95%CI 0.54-0.80) and self-considering adequately carrying out prevention practices (urban: aPR 2.48, 95%CI 2.13-2.89; rural: aPR 2.70, 95%CI 2.27-3.19). CONCLUSION: The frequency of good prevention practices against COVID-19 was less than 30% in both urban and rural areas. There are differences in the factors associated with good preventive practice against COVID-19. Only sex and considering that preventive measures were adequately carried out were associated with good prevention practices in both areas. In view of this, prevention measures should be promoted taking into account cultural principles and considering geographical location in the face of present and future outbreaks or pandemics.

Satisfaction of healthcare workers and patients regarding telehealth service in a hospital in Peru. / Satisfacción del personal de salud y pacientes sobre un servicio de telesalud de un hospital de Perú.

OBJECTIVES.: To evaluate the level of satisfaction of healthcare workers and patients with the telehealth service of the Hospital III Regional Honorio Delgado (HRHD), as well as the maturity level of the telehealth service implementation. MATERIALS AND METHODS.: Cross-sectional, observational study conducted from October to December 2021. The satisfaction of healthcare workers and patients was assessed with the Glaser et al. survey and the Telemedicine Satisfaction Questionnaire (TSQ), respectively. The level of service maturity was assessed using the Pan American Health Organization's instrument for measuring the maturity level of healthcare institutions implementing telemedicine service. RESULTS.: A total of 129 responses were obtained from healthcare workers. Non-physician professionals' satisfaction with the telehealth service was higher than that of physicians (72.5% vs. 18.3%). Of 377 patients, 77.6% stated they were satisfied with the service. Regarding the maturity level, the HRHD telemedicine service had 32% of items in null status, 40.8% in started, 25.2% in advanced, and 2% in ready conditions. CONCLUSIONS.: Physician satisfaction was lower than that of other health professionals. Patients had a moderate-high satisfaction. The maturity level of telehealth implementation in HRHD was oriented towards a null or initiated level. Decision-makers need to consider user satisfaction for the telehealth implementation and the follow-up.

OBJETIVOS.: Evaluar el nivel de satisfacción con el servicio de telesalud del Hospital III Regional Honorio Delgado (HRHD) por parte del personal de salud y los pacientes atendidos, así como el nivel de madurez de implementación de dicho servicio. MATERIALES Y MÉTODOS.: Estudio observacional transversal llevado a cabo desde octubre a diciembre del 2021. La satisfacción del personal de salud y de los pacientes fueron evaluadas con la encuesta de Glaser et al. y el cuestionario Telemedicine Satisfaction Questionnaire (TSQ), respectivamente. El nivel de madurez del servicio se evaluó mediante la herramienta de medición del nivel de madurez de las instituciones de salud para implementar servicios de telemedicina de la Organización Panamericana de la Salud. RESULTADOS.: Se obtuvieron 129 respuestas del personal de salud. El número de profesionales no médicos satisfechos con el servicio de telesalud fue mayor al de médicos (72,5% vs 18,3%). De los 377 pacientes, el 77,6% manifestó estar satisfecho con el servicio. Con respecto al nivel de madurez, el servicio de telemedicina del HRHD cuenta con 32% de ítems en estado nulo, 40,8% en iniciado, 25,2% en avanzado y 2% en listo. CONCLUSIONES.: La satisfacción de los médicos fue menor a la de los otros profesionales de la salud. Los pacientes reportaron una satisfacción moderadamente alta. La implementación del servicio de telesalud en el HRHD se orienta hacia un nivel nulo o iniciado. Es importante que los tomadores de decisiones consideren la satisfacción de usuarios durante la implementación y seguimiento de los servicios de telesalud.