Impacts of Agricultural Pesticide Contamination: An Integrated Risk Assessment of Rural Communities of Eswatini.

Marked reductions in mean annual rainfall associated with climate change in Eswatini in Southern Africa have encouraged the recycling of irrigation water and the increased use of pesticides in agricultural production, raising concerns about potential ecological and health risks due to long-term exposure to pesticide residues in soil and irrigation water. This probabilistic integrated risk assessment used liquid chromatography with tandem mass spectrometry to analyze the concentrations of four commonly used agricultural pesticides (ametryn, atrazine, pendimethalin, and 2,4-dichlorophenoxyacetic acid (2,4-D)) in irrigation water and topsoil samples from farmlands in Eswatini to assess potential ecological and health risks due to exposure. The concentrations of these pesticides ranged from undetectable to 0.104 µg/L in irrigation water and from undetectable to 2.70 µg/g in soil. The probabilistic multi-pathway and multi-route risk assessments conducted revealed hazard indices exceeding 1.0 for all age groups for ametryn and atrazine, suggesting that the daily consumption of recycled irrigation water and produce from the fields in this area may pose considerable health risks. The indices pertaining to ecological risks had values less than 0.1. Adaptation measures are recommended to efficiently manage pesticide use in agriculture, and further research will ensure that agriculture can adapt to climate change and that the general public and ecosystem are protected.

The Soft Prefabricated Orthopedic Insole Decreases Plantar Pressure during Uphill Walking with Heavy Load Carriage.

This study aimed to investigate the effect of varying the hardness of prefabricated orthopedic insoles on plantar pressure and muscle fatigue during uphill walking with a heavy backpack. Fifteen healthy male recreational athletes (age: 20.4 ± 1.0 years, height: 176.9 ± 5.7 cm, weight: 76.5 ± 9.0 kg) wore prefabricated orthopedic insoles with foot arch support; a heel cup with medium (MI), hard (HI), and soft (SI) relative hardnesses; and flat insoles (FI). They performed treadmill walking on uphill gradients with 25 kg backpacks. The plantar pressure and surface electromyographic activity were recorded separately, in 30 s and 6 min uphill treadmill walking trials, respectively. The HI, MI, and SI significantly decreased peak plantar pressure in the lateral heel compared to FI. The MI and SI significantly decreased the peak plantar pressure in the fifth metatarsal compared to FI. The MI significantly reduced the pressure-time integral in the lateral heel compared to FI. The HI significantly increased the peak plantar pressure and pressure-time integral in the toes compared to other insoles, and decreased the contact area in the metatarsal compared to SI. In conclusion, a prefabricated orthopedic insole made of soft material at the fore- and rearfoot, with midfoot arch support and a heel cup, may augment the advantages of plantar pressure distribution during uphill weighted walking.

High pesticide inhalation exposure from multiple spraying sources amongst applicators in Eswatini, Southern Africa.

BACKGROUND: Serious concerns surround the potential risks resulting from inhalation exposure to pesticides amongst agricultural workers when mixing and applying these compounds. In Eswatini (formerly known as Swaziland), Southern Africa, pesticides are widely used to improve the yield and quality of sugar cane production, the largest contributor to the country's economy. We assessed applicators' inhalation exposures from multiple spraying sources to four commonly used herbicides in Eswatini. RESULTS: Analysis of 76 personal air samples by liquid chromatography with tandem mass spectrometry (LC-MS/MS) revealed four pesticides: ametryn, atrazine, pendimethalin and 2,4-dichlorophenoxyacetic acid, with mean concentrations of 36.91, 21.57, 31.05 and 0.89 µg m-3 , respectively. These inhalation exposures are much higher than those recorded in previous similar studies. CONCLUSION: Although all applicators in this study used personal protective equipment (PPE), they nevertheless recorded high levels of inhalation exposure to commonly used pesticides. Our findings suggest that in addition to observing mandated regular changing and cleaning practices with PPE for ultimate personal protection, pesticide applicators should distance themselves from each other when spraying to effectively reduce their exposure to pesticides from multiple spraying sources. Further studies are needed to determine the optimal spraying distance between pesticide applicators. © 2021 Society of Chemical Industry.

Exploring the public-private and company size differences in employees' work characteristics and burnout: data analysis of a nationwide survey in Taiwan.

Distinct differences exist between public-private sector organizations with respect to the market environment and operational objectives; furthermore, among private sector businesses, organizational structures and work conditions often vary between large- and small-sized companies. Despite these obvious structural distinctions, however, sectoral differences in employees' psychosocial risks and burnout status in national level have rarely been systematically investigated. Based on 2013 national employee survey data, 15,000 full-time employees were studied. Sector types were classified into "public," "private enterprise-large (LE)," and "private enterprise-small and medium (SME);" based on the definition of SMEs by Taiwan Ministry of Economic Affairs, and the associations of sector types with self-reported burnout status (measured by the Chinese version of Copenhagen Burnout Inventory) were examined, taking into account other work characteristics and job instability indicators. Significantly longer working hours and higher perceived job insecurity were found among private sector employees than their public sector counterparts. With further consideration of company size, greater dissatisfaction of job control and career prospect were found among SME employees than the other two sector type workers. This study explores the pattern of public-private differences in work conditions and employees' stress-related problems to have policy implications for supporting mechanism for disadvantaged workers in private sectors.

Associations of neighborhood-level workplace violence with workers' mental distress problems: a multilevel analysis of Taiwanese employees.

OBJECTIVE: Workplace violence is known to pose mental health risks. However, whether or not workplace violence in a surrounding area might further increase the risk of mental distress in workers has rarely been examined. METHODS: The study subjects were 9,393 male and 7,716 female employees who participated in a nationwide survey in 2010. Their personal experiences of workplace violence over the past 1 year were ascertained by a standardized questionnaire. Also assessed were their psychosocial work characteristics and mental distress problems. Neighborhood-level workplace violence was computed based on aggregated data at the county level and was categorized into low-, medium-, and high-level categories. Multilevel logistic regression models were constructed to examine the associations between neighborhood-level workplace violence and individual-level mental distress problems, with adjustment of individual-level experience of workplace violence. FINDINGS: The neighborhood-level prevalence of workplace violence ranged from 4.7 to 14.7% in men and from 6.4 to 14.8% in women across 22 counties. As compared with those who live in counties of the lowest tertile of workplace violence, female workers who lived in counties of the highest tertile of workplace violence had a 1.72-fold increased risk for mental distress problems after controlling for individual experience of workplace violence and other psychosocial work characteristics. CONCLUSION: Neighborhood-level workplace violence was associated with poor mental health in female workers. Preventative strategies targeting workplace violence should pay attention to neighborhood factors and gender-specific effects that might influence societal tolerance of abusive work practices and workers' vulnerability to mental health impacts of workplace violence.

Association Between Organization Culture, Health Status, and Presenteeism.

OBJECTIVE: The aim of this study was to examine relationships of organizational culture and health behaviors with presenteeism. METHOD: Data of a self-reported questionnaire were collected from 816 employees, who joined the study on a voluntary basis, in seven enterprises in northern Taiwan. RESULTS: Organizational culture and health behaviors were found to be significantly associated with presenteeism. After adjusting for confounding factors, the number of health complaints seemed to be more suitable than chronic diseases in predicting presenteeism. CONCLUSIONS: This study result implied that advantage could be taken of organizational culture and employees' health behaviors to reduce presenteeism in the workplace.

Acute effects of noise exposure on 24-h ambulatory blood pressure in hypertensive adults.

OBJECTIVE: Noise exposure is associated with elevated blood pressure, but the effects on susceptible workers have not been reported. This repeated-measure study investigated the effects of noise exposure on 24-h ambulatory blood pressure among hypertensive, pre-hypertensive, and normotensive adults. METHODS: We enrolled 113 volunteers in an occupational cohort in 2009. Individual noise exposure and personal blood pressure were measured simultaneously over 24 h on working and non-working days. Linear mixed-effects regressions were used to estimate the effects on SBP and DBP by controlling for potential confounders. RESULTS: Each A-weighted decibel (dBA) increase in a 30-min time-lagged exposure was associated with transient elevations of work-time SBP [0.30 (95% confidence interval: 0.06, 0.54) mmHg] on working days as well as sleep-time SBP [0.39 (0.12, 0.66) mmHg] and DBP [0.33 (0.14, 0.51) mmHg] on non-working days among 19 hypertensive adults. In contrast, 46 normotensive workers had transient increases in work-time SBP [0.16 (0.03, 0.29) mmHg] and DBP [0.25 (0.15, 0.34) mmHg] on working days as well as sleep-time SBP [0.17 (0.06, 0.29) mmHg] and DBP [0.21 (0.14, 0.29) mmHg] on non-working days caused by a 1-dBA increase in the current exposure. All groups had sustained increases in 24-h average ambulatory SBP and DBP induced by noise exposure on 2 days, but the hypertensive workers had the most pronounced increase in SBP. CONCLUSION: Hypertensive adults are more susceptible to noise exposure with a greater effect on ambulatory SBP. These results suggest a need for more protection for this subpopulation.

Changes in psychosocial work conditions in Taiwanese employees by gender and age from 2001 to 2010.

OBJECTIVE: The aim of this study was to examine changes in working hours, shift work, psychological and physical job demands, job control and job insecurity in Taiwanese employees by gender and age during the period of 2001 to 2010. METHODS: The study subjects were 36,750 men and 27,549 women, aged 25-64, from 4 rounds of cross-sectional surveys of representative employees. Psychosocial work conditions were assessed by a validated questionnaire. RESULTS: Regression analyses with adjustment of education and employment grade showed that from 2001 to 2010, the proportions of workers with long working hours (>48 hours/week) (OR=1.4 in men and 1.5 in women) and workers with short working hours (<40 hours/week) (OR=1.3 in both genders) both increased over time, indicating an increasing polarization in the distribution of working hours. Furthermore, the proportions of nonstandard work shifts (OR=1.7 in men and 2.1 in women) and work with high physical demands (OR=1.5 for both gender) increased. There were signs of decreasing levels of job control from 2001 to 2007, which seemed to be more apparent in younger workers than in older workers. However, a slight recovery in decision latitude and opportunity for learning was noticed in later years. The trend in job insecurity was not linear, with the highest prevalence found in 2004. CONCLUSIONS: Our findings suggested that certain aspects of psychosocial work environment had deteriorated in Taiwan. There is a need to raise public awareness about the changing patterns of psychosocial health risks at work as well as their causes and their potential impacts on worker well-being.

Modifying effects of gender, age and enterprise size on the associations between workplace justice and health.

OBJECTIVE: This study examined the distribution of perceived workplace justice and examined the modifying effects of gender, age and enterprise size on the associations between workplace justice and poor health. METHODS: A total of 9,636 male and 7,406 female employees from a national survey conducted in 2007 in Taiwan were studied. A self-administered questionnaire was used to assess workplace justice (9 items), psychosocial work conditions, self-rated health and burnout status. RESULTS: A clear gradient was observed across employment grades, with employees of lower grades reporting lower workplace justice. Government employees were found to have higher levels of workplace justice than those in private sectors, and among those in private sectors, female employees in larger enterprises were found to have significantly lower workplace justice. Multivariate regression analyses showed that employees with workplace justice in the lowest tertile had increased scores in work-related burnout (11.0 and 12.8 points in men and women, respectively) and increased risks for poor self-rated health (OR = 2.5, 2.6) as compared to those with workplace justice in the highest tertile. The associations were stronger in younger groups than in older groups, and in female employees of larger enterprises than those of smaller enterprises. CONCLUSION: Employees with lower socioeconomic position and female employees in larger enterprises might be more likely to be exposed to work practices that give rise to the sense of injustice. The underlying mechanisms for the observed stronger associations between lower workplace justice and poor health in younger groups and in workers of larger enterprises deserve further investigation.

Six-month follow-up study of health markers of nanomaterials among workers handling engineered nanomaterials.

The aim of this study was to identify the health hazards and possible exposure surveillance markers of workers exposed to nanoparticles during manufacturing and application in comparison to a group of unexposed workers. For this longitudinal study, we recruited 158 nanomaterial-handling workers and 104 non-exposed workers from 14 manufacturing plants in Taiwan (baseline). Among them, 124 nanomaterial-handling workers and 77 unexposed workers were monitored 6 months later. We investigated pulmonary and cardiovascular disease markers, inflammation and oxidative stress markers, antioxidant enzymes and genotoxicity markers. Antioxidant enzymes (superoxide dismutase, glutathione peroxidase) and cardiovascular markers (vascular cell adhesion molecule, paraoxonase) were significantly associated with nanomaterial-handling during the 6-month follow-up period. In addition, the small airway damage marker (Clara cell protein 16) and lung function test parameters were also significantly associated with handling nanomaterials. The study markers and lung function tests are possible markers that could be useful for surveillance of nanomaterial-handling workers.

Combined effects of noise, vibration, and low temperature on the physiological parameters of labor employees.

Noise, vibration, and low temperature render specific occupational hazards to labor employees. The purpose of this research was to investigate the combined effects of these three physical hazards on employees' physiological parameters. The Taguchi experimental method was used to simulate different exposure conditions caused by noise, vibration, and low temperature, and their effects on the physiological parameters of the test takers were measured. The data were then analyzed using statistical methods to evaluate the combined effects of these three factors on human health. Results showed that the factor that influenced the finger skin temperature, manual dexterity, and mean artery pressure (MAP) most was air temperature, and exposure time was the second most influential factor. Noise was found to be the major factor responsible for hearing loss; in this case, hand-arm vibration and temperature had no effect at all. During the study, the temperature was confined in the 5-25°C range (which was not sufficient to study the effects at extremely high- and low-temperature working conditions) because the combined effects of even two factors were very complicated. For example, the combined effects of hand-arm vibration and low temperature might lead to occupational hazards such as vibration-induced white finger syndrome in working labors. Further studies concerning the occupational damage caused by the combined effects of hazardous factors need to be conducted in the future.

Work-related fatigue among medical personnel in Taiwan.

BACKGROUND/PURPOSE: Work-related fatigue among medical personnel is a major concern for patient safety, however heavy on-call duty is common in many hospitals. The purpose of this study was to investigate the prevalence of self-reported work-related fatigue and its associated factors. METHODS: A cross-sectional survey of 1833 participants was conducted in two hospitals in Taipei City, Taiwan, using a self-administered questionnaire. Participants reported their demographic characteristics, health-related behavior, health status and symptoms, and work-related fatigue during the past 3 months. RESULTS: The prevalence of work-related fatigue among the 1833 participants was 30.9%. Younger participants (20-29 years old) were more likely to report work-related fatigue than older participants (40-65 years old) [adjusted odds ratio (aOR) = 1.55, 95% confidence interval (CI) = 1.18-2.01]. Physicians, nurses, and medical technicians were more likely to report work-related fatigue symptoms than administrative personnel (aOR = 2.30, 95% CI = 1.57-2.79; aOR = 2.83, 95% CI = 1.87-3.99; and aOR = 2.01, 95% CI = 1.12-3.06, respectively). Those who drank coffee more than five times a week were more likely to report work-related fatigue than those who did not drink coffee at all (aOR = 2.53, 95% CI = 1.25-1.93). Participants with poor and very poor self-reported health were more likely to report work-related fatigue (aOR = 1.80, 95% CI = 1.26-2.38) than those who reported that their health was fair, good, or very good. CONCLUSION: We identified factors associated with work-related fatigue among hospital workers in Taipei City. These findings can be applied toward on-the-job training and the development of preventive measures for occupational safety in general hospitals.

The effects of exercise program on burnout and metabolic syndrome components in banking and insurance workers.

To explore the effectiveness of exercise program for banking and insurance workers and clarify the association between exercise, burnout, and metabolic syndrome components. In the process of the study, a practicable worksite exercise program was developed for bank and insurance enterprises. A three-month (12-wk) exercise course was conducted, and its benefits evaluated. Levels of burnout and metabolic syndrome components were analyzed after exercise intervention. After intervention, the indicators of burnout and metabolic syndrome components were significantly improved in both low and high intensity groups, and the improvement were expressed in reduction of waist circumference, systolic blood pressure, person burnout and work-related burnout. A dose-response of burnouts and metabolic syndrome components with exercise intensity are shown (p<0.05). Metabolic syndrome components were independently associated with burnout and exercise intensity in the crude model. After adjustment for potential confounders, waist circumference and systolic blood pressure differences showed significant associations with exercise intensity (p<0.05). This study demonstrated an effective approach to worksite exercise intervention and exercise intensity played an important role to alleviate damage between burnouts and metabolic syndrome components.

The influence of age on the distribution of self-rated health, burnout and their associations with psychosocial work conditions.

OBJECTIVE: Self-rated health (SRH) and burnout are commonly used health indicators. This study was designed to examine the age-specific patterns of SRH and burnout and their correlations with self-reported disease symptoms, and to investigate the moderating effects of age on the associations of psychosocial work conditions with these two health measures. METHODS: Study subjects were 20,454 male and 16,875 female employees from 2 representative surveys conducted in 2007 and 2010 in Taiwan. SRH was assessed by a single item and burnout was assessed by the general burnout subscale of the Copenhagen Burnout Inventory (CBI). Psychosocial work conditions including working hours, psychological and physical job demands, job control, job insecurity and workplace justice were assessed by a validated questionnaire. RESULTS: Older workers were at higher risk for poor SRH which was correlated with the presence of multiple disease symptoms. In contrast, employees aged 30-40 years had higher burnout which was strongly correlated with emotional disturbance. Among all the examined work factors, low workplace justice was found to be the most predominant predictor for poor SRH and high burnout, and the associations were more profound in younger workers than in older workers. CONCLUSION: SRH and burnout were differentially related to age, and there were evidences of moderating effects of age on the associations between psychosocial work conditions and health. Researchers and health practitioners should pay attention to the influence of age when using the measures of SRH and burnout as indicators to detect health risk in association with adverse psychosocial work conditions.

Effect of low frequency noise on the echocardiographic parameter E/A ratio.

The hearing condition of the Taiwanese aerospace maintenance workers affected by the low frequency noise had not been reported. The purpose of this research is to clarify the maintenance workers' health effect when exposed to low frequency and/or general noises and to understand the relationship between the variations of the worker's echocardiographic E/A ratio and the low frequency noise. The low frequency noise monitoring and echocardiographic E/A ratio results obtained for 213 aerospace maintenance workers indicated that the workers' hearing loss was more serious at high frequency 4k and 6k when exposed to the low frequency noise and could be more than 40 dB. The abnormality of echocardiographic E/A ratio was also higher than that of control group.

Alcohol dependence, consumption of alcoholic energy drinks and associated work characteristics in the Taiwan working population.

AIMS: To examine the association between work characteristics and the risk of alcohol dependence across different employment types and occupations, including the pattern of alcohol consumption in the form of energy drinks and its association with alcohol dependence. METHODS: A total of 13,501 men and 8584 women participated in a national survey in Taiwan. Alcohol dependence was defined as ≥2 points in the CAGE questionnaire. A self-administered questionnaire recorded drinking behaviors, consumption of alcoholic energy drinks, employment type, occupation and a number of psychosocial work stressors, namely job demands, job control, employment security and workplace justice. RESULTS: Of the total, 9.4% of men and 0.8% of women were CAGE-positive, and 6.0% of men and 0.7% of women regularly consumed alcoholic energy drinks. In male and female regular consumers of alcoholic energy drinks, 38.7 and 23.3%, respectively, were alcohol-dependent. Multivariate regression analyses showed that male employees in manual skilled occupations, with lower workplace justice, having weekly working hours <40 h and on piece-rated or time-based pay systems were at higher risks of alcohol dependence. CONCLUSION: Certain occupational groups and workers with adverse psychosocial work characteristics should be targets for prevention of alcohol dependence. Alcoholic energy drink consumption should be taken into consideration while studying alcohol dependence in the work population in Taiwan.

Atypical work schedules are associated with poor sleep quality and mental health in Taiwan female nurses.

PURPOSE: To investigate the effects of shift work schedules on sleep quality and mental health in female nurses in south Taiwan. METHODS: This study recruited 1,360 female registered nurses in the Kaohsiung area for the first survey, and among them, 769 nurses had a rotation shift schedule. Among the 769 rotation shift work nurses, 407 completed another second survey 6-10 months later. Data collection included demographic variables, work status, shift work schedule, sleep quality (Pittsburgh Sleep Quality Index), and mental health (Chinese Health Questionnaire-12). RESULTS: Nurses on rotation shift had the poor sleep quality and mental health compared to nurses on day shift. The nurses on rotation shift had a relatively higher OR of reporting poor sleep quality and poor mental health (OR, 2.26; 95% CI, 1.57-3.28; and OR, 1.91; 95% CI, 1.39-2.63, respectively). Additionally, rotation shift nurses who had ≥2 days off after their most recent night shifts showed significantly improved sleep quality and mental health (PSQI decreased of 1.23 and CHQ-12 decreased of 0.86, respectively). Comparison of sleep quality between the first and second surveys showed aggravated sleep quality only in nurses who had an increased frequency of night shifts. CONCLUSION: Female nurses who have a rotation shift work schedule tend to experience poor sleep quality and mental health, but their sleep quality and mental health improve if they have ≥2 days off after their most recent night shifts. This empirical information is useful for optimizing work schedules for nurses.

Characteristics of microbial aerosols released from chicken and swine feces.

Bioaerosols generated during livestock and poultry production are significant occupational hazards. This study investigates the characteristics of bioaerosols released from animal feces. Fresh feces from pigs and chickens were obtained and tested in a controlled-environment facility. Airborne viable (culturable) bacteria and fungi were sampled hourly for 48 hr. The predominant species were identified via polymerase chain reaction analysis. The number of bacterial colonies released from chicken feces increased gradually, peaked at approximately 20 hr, and remained relatively constant to test end; however, the bacterial colonies released from swine feces did not increase significantly. The chicken feces released significantly (P < 0.05) more bacterial aerosols than swine feces over 40 hr, by approximately 1 order of magnitude. However, the difference in total fungal aerosols released from the two feces types was relatively small (30-40%) and insignificant (P > 0.05). Aerosols sized between approximately 0.65 and 1.1 microm were predominant for bacteria, whereas aerosols sized between approximately 2.1 and 3.3 microm prevailed for fungi. Genera Stenotrophomonas were the predominant bacterial aerosols, whereas Cladosporium and Acremonium accounted for the greatest amounts of fungi from chicken and swine feces, respectively. More than 1000 culturable bacterial colonies can be released from 1 g of chicken feces per hour, and approximately 80% of these bioaerosols are respirable. Most bacterial aerosols released from swine and chicken feces were opportunistic human pathogens; thus, the significance of their presence warrants further investigations.

Glycine N-methyltransferase affects urinary 1-hydroxypyrene and 8-hydroxy-2'-deoxyguanosine levels after PAH exposure.

OBJECTIVES: The object of this study was to assess the modulating effects of genetic polymorphisms of glycine N-methyltransferase (GNMT) genotypes on 1-hydroxypyrene (1-OHP) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) in urine from coke-oven workers, consistently exposed to polycyclic aromatic hydrocarbons (PAHs). METHODS: The study participants included 289 coke-oven workers from a steel company in Taiwan. Personal air samples, spot urine samples, peripheral blood samples, and questionnaires were used to quantify PAH exposure, oxidative DNA damage, GNMT gene polymorphisms, demographic data, and environmental pollutants. RESULTS: Urinary 1-OHP level, GNMT STRP1 genotype, and worksite were significant predictors of urinary 8-OHdG levels after adjustments were made for covariates. CONCLUSIONS: This study suggests that GNMT STRP1 could modulate urinary 1-OHP and 8-OHdG levels in coke-oven workers exposed to PAHs.

Influences of shift work on fatigue among nurses.

AIM: To compare the symptoms of fatigue and physiological indices in nurses who work during the day with nurses who work in shifts. METHOD: One-hundred and seven nurses were recruited and asked to assess their symptoms of fatigue before their work commenced and after it finished. RESULTS: Using logistic regression analysis adjusted for covariates, it was found that nurses who work in shifts were more fatigued than nurses who work during the day (odds ratio = 2.44, P < 0.10). There was a significant difference regarding critical flicker fusion in the two groups of nurses (P = 0.032), and nurses who work in shifts had poorer physiological indices than nurses who work during the day. CONCLUSION: It is clear that differing work schedules result in differing levels of fatigue, with shift work attributing to higher levels than day work. IMPLICATIONS FOR NURSING MANAGEMENT: Nurse managers need to take into account the fatiguing effects of different work schedules when designing rostering patterns.