ABSTRACT
We tested whether propofol or Intralipid inoculated with Staphylococcus epidermidis would promote bacterial growth within an intravenous (IV) injection hub, a site prone to bacterial contamination. In tubes incubated under optimal conditions, S epidermidis exhibited growth in Intralipid, but not in propofol. In contrast, within the IV hub incubated with either propofol or intralipid at room temperature, S epidermidis bacterial numbers declined with time, and virtually no contamination remained after 12 hours. These data suggest that certain IV lines are inhospitable for S epidermidis.
Subject(s)
Drug Contamination , Equipment Contamination , Phospholipids/analysis , Propofol/analysis , Soybean Oil/analysis , Staphylococcus epidermidis/growth & development , Vascular Access Devices/microbiology , Emulsions/administration & dosage , Emulsions/analysis , Injections, Intravenous , Microbial Viability , Phospholipids/administration & dosage , Propofol/administration & dosage , Soybean Oil/administration & dosage , Time FactorsABSTRACT
Pseudotumor cerebri syndrome (PTCS) is a rare disorder chiefly observed in obese women of childbearing age. We describe a case of a parturient with PTCS managed successfully with an intrathecal catheter, after inadvertent dural puncture, for labor analgesia, surgical anesthesia, and treatment of headache because of intracranial hypertension during the peripartum period. Prolonged placement of the intrathecal catheter (i.e., >24 hours) may have contributed to the absence of postdural puncture headache symptoms and an uneventful postpartum period. Intrathecal catheter placement may therefore be a viable option in patients with PTCS should inadvertent dural puncture occur.
