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1.
PLoS One ; 17(11): e0276170, 2022.
Article in English | MEDLINE | ID: mdl-36395167

ABSTRACT

The global societal impact of the COVID-19 pandemic is incalculable with profound social suffering, deep economic hardships and enforced closure of schools, businesses, and higher learning institutions through the imposition of lockdown and social distancing in mitigation of the spread of the SARS-Cov-2 infection. Institutions have had to hastily migrate teaching, learning and assessment to online domains, at times with ill-prepared academics, students and institutions and with unwelcome and disorienting consequences. Our study surveyed perspectives of faculty at the University of Zimbabwe Faculty of Medicine and Health Sciences (UZFMHS) towards the hastily adopted online teaching, learning and assessment implemented in response to the mitigation of the COVID-19 pandemic. Twenty nine (29) faculty in all the major disciplines and career hierarchy. There were mixed responses regarding the use of this modality for teaching, learning and assessment: training before online teaching, learning and assessment, advantages and disadvantages, cost effectiveness, effectiveness for teaching, learning and assessment, effect on student feedback, disruptions from internet connectivity issues, interaction with students, suitability for practical training, and barriers to online teaching, learning and assessment. These results would enable the UZFMHS develop institutional and personalised approaches that would enable execution of online teaching, learning and assessment under the current and post COVID-19 pandemic.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , Pandemics , Communicable Disease Control , SARS-CoV-2 , Health Occupations , Faculty
2.
J Oral Maxillofac Surg ; 67(1): 22-31, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19070744

ABSTRACT

PURPOSE: To present our experience with the clinical features and management of black African patients with xeroderma pigmentosum (XP). PATIENTS AND METHODS: Twelve patients with XP were seen over a 25-year period, and were retrospectively reviewed for age, gender, clinical features, treatment, and follow-up. RESULTS: There were 8 females and 4 males with an age range of 3 to 18 years. One patient, the longest survivor, was followed until death at 18 years. Nine patients had the severe form of XP and 3 had the mild form. All patients had early ocular involvement with photophobia and early blindness. Squamous cell carcinoma (SCC) was present on the skin, lip, and tongue in most patients. One patient had ocular surface SCC. There was marked skin photosensitivity. No history of consanguinity was noted in the parents of the patients. Surgery was the treatment modality of choice. Follow-up was poor. CONCLUSION: XP is uncommon in our black population, and presents in the severe form with SCC as the malignant skin, lip, and tongue lesion. It is common in early childhood with severe photosensitivity, photophobia, and eventual blindness. Follow-up is difficult in our environment.


Subject(s)
Black People , Carcinoma, Squamous Cell/pathology , Mouth Neoplasms/pathology , Skin Neoplasms/pathology , Xeroderma Pigmentosum/ethnology , Adolescent , Carcinoma, Squamous Cell/ethnology , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/therapy , Child , Child, Preschool , Female , Humans , Male , Mouth Neoplasms/ethnology , Mouth Neoplasms/mortality , Mouth Neoplasms/therapy , Retrospective Studies , Severity of Illness Index , Sex Factors , Skin Neoplasms/ethnology , Skin Neoplasms/mortality , Skin Neoplasms/therapy , Xeroderma Pigmentosum/mortality , Xeroderma Pigmentosum/pathology , Xeroderma Pigmentosum/therapy , Zimbabwe
4.
J Oral Maxillofac Surg ; 66(3): 475-85, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18280380

ABSTRACT

PURPOSE: This retrospective study describes the clinical features and management of noma (cancrum oris) in patients with HIV and AIDS. PATIENTS AND METHODS: Records of 48 consecutive patients with noma (cancrum oris) seen between July 2002 and November 2006 were reviewed for age, gender, clinical features, and management. Other reports on noma in HIV and AIDS in Zimbabwe were also reviewed. RESULTS: There were 48 patients included; 35.4% (n = 17) were males, of which 64.7% (n = 11) were children (16 years and younger) and 35.3% (n = 6) were adults; 64.6% (n = 31) were females, out of which 87.1% (n = 27) were children and 12.9% (n = 4) were adults. The average age was 14.2 years (range, 3 to 30 years) for males and 9.2 years (range, 1 to 36 years) for females. The average age for the entire group was 11 years (range, 1 to 36 years). All patients were HIV-positive by the ELISA method. Only 13 patients had CD4 cell and CD8 cell count obtained, ranging from 10 to 594 cells/microL with a CD4/CD8 ratio ranging from 0.02 to 0.45. Only 5 patients had microbiologic investigations conducted, isolating Staphylococcus aureus, Klebsiella species, group D Streptococcus, and group B hemolytic Streptococcus. Isolated cheek defect (37.5%) was most common, followed by the type I and type IV defect (25% each). Administration of antibiotics, nutritional support, wound debridement, and sequestrectomy were conducted before definitive reconstructive surgery. Facial reconstruction was performed using distant and local advancement flaps. No bony reconstruction was performed. Satisfactory results were achieved with minimal infection and flap breakdown. Follow-up was difficult; patients were lost to follow-up within 6 to 12 months after surgery. CONCLUSION: Noma cases are on the increase in line with the current HIV and AIDS epidemic. Female children appear to be more commonly affected than their male counterparts. Reconstructive surgery is possible in patients with low CD4/CD8 ratios because of HIV infection.


Subject(s)
HIV Infections/complications , Immunocompromised Host/immunology , Noma/therapy , Oral Surgical Procedures/methods , Plastic Surgery Procedures/methods , Acquired Immunodeficiency Syndrome/complications , Adolescent , Adult , CD4 Antigens/analysis , CD4 Lymphocyte Count , CD4-CD8 Ratio , CD8 Antigens/analysis , Child , Child, Preschool , Female , Humans , Male , Noma/immunology , Noma/microbiology , Nutrition Therapy , Retrospective Studies , Sex Factors , Zimbabwe
5.
J Oral Maxillofac Surg ; 65(6): 1117-20, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17517294

ABSTRACT

PURPOSE: To present our experience on the epidemiology, clinical features, management, and survival of patients with oral malignant melanoma. PATIENTS AND METHODS: Records of patients with a histologic diagnosis of primary oral mucosal malignant melanoma seen over a 23-year period were retrospectively reviewed. RESULTS: There were 6 females and 2 males, ranging in age from 18 to 60 years; 4 cases in the maxilla, 2 in the mandible, 1 on the lower lip, and 1 on the buccal mucosa. Local recurrences developed in 2 patients who eventually died with clinical metastatic cervical nodal disease. Follow-up ranged from 6 months to 16 years 3 months. Surgery was the only treatment available. CONCLUSION: Primary oral mucosal melanoma is rare, with a 3 to 1 female to male ratio and an average age of 41.7 years at presentation. It is most common in the maxilla and has poor prognosis despite apparent adequate local surgical control.


Subject(s)
Melanoma/epidemiology , Mouth Neoplasms/epidemiology , Adolescent , Adult , Female , Follow-Up Studies , Humans , Lip Neoplasms/epidemiology , Lymphatic Metastasis , Male , Mandibular Neoplasms/epidemiology , Maxillary Neoplasms/epidemiology , Middle Aged , Mouth Mucosa/pathology , Neck , Neoplasm Recurrence, Local/epidemiology , Retrospective Studies , Sex Factors , Zimbabwe/epidemiology
6.
J Oral Maxillofac Surg ; 65(1): 79-82, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17174768

ABSTRACT

PURPOSE: To document the clinical features, management, and outcome of ranulas in Zimbabwe. METHODS: A retrospective review of clinical and pathologic records of 83 patients with ranulas who presented during the period of January 1981 to September 2003 was undertaken. RESULTS: Thirty-six (43.4%) of the ranulas were in males and 47 (56.6%) in females. Sixty-one (73.5%) were in the 0 to 10-year-old age group. Oral ranulas (92.8%) were equally distributed on the right and left sublingual region. Six (7.2%) were plunging ranulas. In a study group of 38 patients, 88.5% of ranula patients were HIV-positive with 95% of them in the 0 to 10-year-old age groups. Excision of ranula with sublingual gland removal was done in 80.7% of the cases with 0% recurrence; marsupialization (cavity left open and cavity packed) was done in 12% (n = 10) of the patients with 20% (n = 2) recurrence. CONCLUSIONS: Female predominance with no right or left sublingual region predilection was noted. Ranula was most common in the 0 to 10-year-old age group; 95% of this group were HIV positive. HIV salivary gland disease could be an etiologic factor. No recurrence was observed when the ranula was excised along with removal of the sublingual gland. Plunging ranula is uncommon.


Subject(s)
Ranula/epidemiology , Adolescent , Adult , Age Factors , Child , Child, Preschool , Female , HIV Seropositivity/epidemiology , Humans , Infant , Male , Middle Aged , Mouth Floor/pathology , Recurrence , Retrospective Studies , Salivary Gland Diseases/epidemiology , Sex Factors , Sublingual Gland , Zimbabwe/epidemiology
7.
Med Oral Patol Oral Cir Bucal ; 11(5): E437-9, 2006 Aug 01.
Article in English | MEDLINE | ID: mdl-16878062

ABSTRACT

Lipomas are among the most common tumors of the human body. However, they are uncommon in the oral cavity. In the oral cavity they present as a slow growing, painless, and asymptomatic yellowish submucosal mass. Surgical excision is the treatment of choice with recurrence not expected. They have been known to grow to large sizes causing mastication and speech difficulties. The usual lesions consist of a well circumscribed, lobulated mass of mature fat cells. In other situations the covering mucosa becomes ulcerated and presents difficulties in diagnosis. The present report is of a patient who presented with a gigantic lipoma on the tip of the tongue which had been present for 3 years. She now had difficulty with speech and mastication as the tongue tumor now completely filled the oral cavity. An incision biopsy confirmed the tumor as lipoma. The tumor was surgically excised with restoration of normal tongue function, speech and masticatory capacity. Histopathologic examination of the excised tumor confirmed that it was a lipoma.


Subject(s)
Lipoma/pathology , Tongue Neoplasms/pathology , Female , Humans , Lipoma/surgery , Middle Aged , Tongue Neoplasms/surgery
8.
Oral Oncol ; 42(2): 184-9, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16256417

ABSTRACT

Squamous cell carcinoma accounts for approximately 90% of oral malignancies. The objective of this study was to document the gender, age, sub-site distribution and histologic differentiation of squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population. Hospital records of patients with a histologic diagnosis of squamous cell carcinoma of the oral cavity, maxillary antrum and lip seen at Harare Central Hospital and Parirenyatwa Hospital in Zimbabwe during the period January 1982-December 1991 were reviewed. 20.8% (n = 358/1723) were squamous cell carcinoma of the oral cavity, maxillary antrum and lip. Age ranged from 3 to 70years with a 2:1 male:female ratio. Peak incidence in both sexes were in the 41-50 and 51-60years age groups. Sub-site distribution was mandibular gingiva 18.4%, tongue 17.9%, floor of the mouth 16.2%, maxillary gingiva 9.2%, buccal mucosa 9.2%, maxillary antrum 12.6%, hard palate 7.8%, soft palate 4.8%, lower lip 2.8% and upper lip 1.1%. 64.8% were well differentiated, 24.8% moderately differentiated and 10.4% poorly differentiated. The mandibular gingiva, floor of the mouth and tongue were most commonly affected. Lip squamous cell carcinoma was uncommon. Well-differentiated squamous cell carcinoma was most common in the 41-60 years age group.


Subject(s)
Carcinoma, Squamous Cell/epidemiology , Developing Countries , Maxillary Sinus Neoplasms/epidemiology , Mouth Neoplasms/epidemiology , Adolescent , Adult , Age Distribution , Aged , Carcinoma, Squamous Cell/pathology , Cell Differentiation , Child , Child, Preschool , Female , Humans , Lip Neoplasms/epidemiology , Lip Neoplasms/pathology , Male , Maxillary Sinus Neoplasms/pathology , Middle Aged , Mouth Neoplasms/pathology , Sex Distribution , Zimbabwe/epidemiology
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