ABSTRACT
Historically, the use of medial unicompartmental knee arthroplasty (mUKA) as treatment for end-stage anteromedial osteoarthritis (AMOA) of the knee was limited by contraindications due to age, weight, and activity level; however, now evidence-based, validated, and less selective criteria are used rendering nearly 50% of end-stage OA patients eligible for mUKA. Recent studies have showcased benefits, such as shorter hospital stays, cost efficiency, and comparable functional outcomes to total knee arthroplasty (TKA). Notably, revision rates have been shown to markedly decrease with increased usage, with an ideal usage of >â¯30% but an acceptable usage of 20-60%. The usage of unicompartmental knee arthroplasty (UKA) varies among countries, with Denmark achieving a notably higher usage compared to Sweden, the UK, the Netherlands, the USA and Germany. This article investigates potential factors contributing to Denmark having a higher national usage of mUKA, surpassing the recommended threshold of a usage >â¯20%. We explore the tradition for national alliances and streamlined surgical education as possible explanations of this development. These insights offer valuable perspectives for potentially optimizing surgical approaches and implant choices in the surgical treatment of end-stage AMOA of the knee across diverse healthcare settings, underscoring the impact of collective strategies in advancing knee arthroplasty practices, ultimately benefiting patients.
Subject(s)
Arthroplasty, Replacement, Knee , Osteoarthritis, Knee , Humans , Osteoarthritis, Knee/surgery , Reoperation , Knee Joint/surgery , DenmarkABSTRACT
PURPOSE: We aimed to evaluate the effectiveness of different antibiotic regimens for the treatment of parapharyngeal abscess (PPA) and characterize patients, who suffered potentially preventable complications (defined as death, abscess recurrence, spread of infection, or altered antibiotic treatment because of insufficient progress). METHODS: Sixty adult patients with surgically verified PPA were prospectively enrolled at five Danish Ear-nose-throat departments. RESULTS: Surgical treatment included internal incision (100%), external incision (13%), and tonsillectomy (88%). Patients were treated with penicillin G ± metronidazole (n = 39), cefuroxime ± metronidazole (n = 16), or other antibiotics (n = 5). Compared to penicillin-treated patients, cefuroxime-treated patients were hospitalized for longer (4.5 vs 3.0 days, p = 0.007), were more frequently admitted to intensive care (56 vs 15%, p = 0.006), underwent external incision more frequently (31 vs 5%, p = 0.018), and suffered more complications (50 vs 18%, p = 0.022), including re-operation because of abscess recurrence (44 vs 3%, p < 0.001). Nine patients suffered potentially preventable complications. These patients displayed significantly higher C-reactive protein levels, received antibiotics prior to admission more frequently, underwent external incision more commonly, and were admitted to intensive care more frequently compared to other patients. CONCLUSION: The majority of patients with PPA were effectively managed by abscess incision, tonsillectomy, and penicillin G ± metronidazole. Cefuroxime-treated patients were more severely ill at time of admission and had worse outcome compared to penicillin-treated patients. We recommend penicillin G + metronidazole as standard treatment for patients with PPA, but in cases with more risk factors for potentially preventable complications, we recommend aggressive surgical and broadened antibiotic therapy, e.g. piperacillin-tazobactam.
Subject(s)
Pharyngeal Diseases , Tonsillectomy , Abscess/drug therapy , Abscess/etiology , Abscess/surgery , Adult , Anti-Bacterial Agents/therapeutic use , Humans , Metronidazole/therapeutic use , Pharyngeal Diseases/drug therapyABSTRACT
BACKGROUND: Use of suction drain after superficial parotidectomy (SP) is based on national consensus considered best practice, but there is no evidence on the effect of the treatment. The aim of the present study is to evaluate the effectiveness of drainage after SP by evaluating the rate of complications after SP in relation to the (ie, duration) of drainage and tumor size. METHODS: Retrospective analysis was performed involving data from all consecutive patients undergoing SP at the Ear, Nose, and Throat department, Regional Hospital West Jutland, Denmark, between January 1, 2011, and December 31, 2017. Demographics including comorbidity, medication, tumor size, postoperative secretion through the drainage, as well as complications (hematoma, seroma, infection, fistulas, Frey syndrome, facial nerve palsy) were registered. Patients with secretion below 25 mL were compared to patients with secretion above 25 mL, that is, drainage less than 24 hours versus longer than 24 hours. Results: Two hundred five consecutive patients undergoing SP were enrolled. The overall risk of postoperative infection was 16.2%. Ten of 33 patients with infection were also diagnosed with an hematoma or seroma. The risk of infection increased with secretion above 25 mL (27.2%) compared to patients with less than 25 mL (13.1%; P = .0318). The same accounts for the risk of seromas/hematomas (P = .0055). We found no evidence that demographics or comorbidity correlated to the secretion in the drainage, but there is a tendency toward male gender having a higher risk off secretion above 25 mL (odds ratio 1.39). CONCLUSION: Overall, the risk of complications after SP increased with secretion beyond 25 mL (ie, drainage for more than 24 hours). This applied in particular to infections and seromas/hematomas demanding treatment. The use of routine drainage after SP is questionable, and a randomized trial is warranted to unravel the necessity of postoperative drainage.
Subject(s)
Parotid Gland/surgery , Parotid Neoplasms/surgery , Postoperative Care , Postoperative Complications/prevention & control , Suction , Facial Paralysis/diagnosis , Facial Paralysis/prevention & control , Female , Hematoma/diagnosis , Humans , Male , Middle Aged , Parotid Neoplasms/pathology , Postoperative Complications/diagnosis , Retrospective Studies , Salivary Gland Fistula/diagnosis , Salivary Gland Fistula/prevention & control , Seroma/diagnosis , Seroma/prevention & control , Sex Factors , Surgical Wound Infection/diagnosis , Surgical Wound Infection/prevention & control , Sweating, Gustatory/diagnosis , Sweating, Gustatory/prevention & control , Tumor BurdenABSTRACT
We aimed to describe the microbiology of parapharyngeal abscess (PPA) and point out the likely pathogens using the following principles to suggest pathogenic significance: (1) frequent recovery, (2) abundant growth, (3) growth in relative abundance to other microorganisms, (4) percentage of the isolates recovered in both absolute and relative abundance, (5) more frequent recovery in PPA pus compared with tonsillar surface and tissue. Comprehensive bacterial cultures were performed on specimens obtained from adult patients (n = 60) with surgically verified PPA, who were prospectively enrolled at five Danish ear-nose-throat departments. The prevalent isolates (in PPA pus) were unspecified anaerobes (73%), non-hemolytic streptococci (67%), Streptococcus anginosus group (SAG) (40%), Corynebacterium spp. (25%), Neisseria spp. (23%), Fusobacterium spp. (22%), Fusobacterium necrophorum (17%), Prevotella spp. (12%), and Streptococcus pyogenes (10%). The bacteria most frequently isolated in heavy (maximum) growth were unspecified anaerobes (60%), SAG (40%), F. necrophorum (23%), and Prevotella spp. (17%). The predominant microorganisms (those found in highest relative abundance) were unspecified anaerobes (53%), SAG (28%), non-hemolytic streptococci (25%), F. necrophorum (15%), S. pyogenes (10%), and Prevotella spp. (10%). Four potential pathogens were found in both heavy growth and highest relative abundance in at least 50% of cases: F. necrophorum, Prevotella spp., SAG, and S. pyogenes. SAG, Prevotella spp., F. necrophorum, S. pyogenes, and Bacteroides spp. were recovered with the same or higher frequency from PPA pus compared with tonsillar tissue and surface. Our findings suggest that SAG, F. necrophorum, Prevotella, and S. pyogenes are significant pathogens in PPA development.
Subject(s)
Abscess/microbiology , Bacteria/isolation & purification , Parapharyngeal Space/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Bacteria/classification , Female , Humans , Male , Middle Aged , Parapharyngeal Space/microbiology , Young AdultABSTRACT
INTRODUCTION: Acquired nasolacrimal drainage obstruction (ANLDO) is a common ophthalmic problem with symptoms like epiphora and dacryocystitis. The standard surgery for ANLDO is dacrocystorhinostomy (DCR) in which the lacrimal sac is connected directly to the nose. There are two types of DCR, external (exDCR) and endonasal (enDCR). Our aim was to determine the total outcome of enDCR and specifically to analyze the success rate in relation to obstruction levels as there only have been few former reports on these aspects. MATERIAL AND METHODS: A retrospective chart review was performed at the Department of Otorhinolaryngology at the Hospital of Holstebro in the 2005-2010 period. All patients were evaluated by an ophthalmologist before surgery. The ophthalmologist categorized the site of obstruction as proximal (from punctum to the end of the common canaliculus) or distal (saccus and the nasolacrimal duct). The need for additional nasal surgery was evaluated by an otorhinolaryngologist. The surgical outcome was evaluated at the second follow-up six months after surgery and the subjective improvement and the patency of the neo-ostium were determined. RESULTS: A total of 61 operations were performed of which 55 were included. The success rate after enDCR was 91%. Categorizing the level of obstruction, 41% were distal of which 92% were successful, and 59% were proximal of which 90% were successful. CONCLUSION: We suggest enDCR for both distal and proximal stenosis of the lacrimal system as the obstruction level seems to have no influence on the success rates. FUNDING: not relevant. TRIAL REGISTRATION: not relevant.