1.
J Alzheimers Dis
; 90(1): 61-68, 2022.
Article
in English
| MEDLINE
| ID: mdl-36093702
ABSTRACT
We examined ethnoracial differences in fatty acid binding protein (FABP)-a family of intracellular lipid carriers-and clarified FABP3 associations with gray and white matter. Relative to Mexican Americans (MAs), FABP3 was higher in Non-Hispanic Whites (NHWS, pâ<â0.001). Regressions revealed, independent of traditional AD markers, FABP3 was associated with neurodegeneration (Bâ=â-0.08, pâ=â0.003) and WMH burden (Bâ=â0.18, pâ=â0.03) in MAs, but not in NHWs (psâ>â0.18). Findings suggest FABP3 is related to neural health within MAs and highlight its potential as a prognostic marker of brain health in ethnoracially diverse older adults.