1.
Hemoglobin
; 41(3): 216-217, 2017 May.
Article
in English
| MEDLINE
| ID: mdl-28870138
ABSTRACT
The gene for hereditary persistence of fetal hemoglobin (HPFH) in the Caribbean is much more common than previously estimated. To avoid labeling persons with the benign syndrome Hb S (HBB: c.20A>T)/HPFH as a disease and wasting scarce resources, parental studies are recommended when newborn screening reveals a pattern consistent with an SS phenotype.
Subject(s)
Fetal Hemoglobin/genetics , Hemoglobin, Sickle/genetics , Hemoglobinopathies/diagnosis , Hemoglobinopathies/genetics , Alleles , Gene Frequency , Genetic Association Studies , Genotype , Humans , Infant, Newborn , Neonatal Screening , Phenotype
2.
Br J Haematol
; 172(4): 634-6, 2016 Feb.
Article
in English
| MEDLINE
| ID: mdl-26123225