ABSTRACT
An excellent veterinary surgeon and a great colleague; his sharply observed humour and deep empathy were much appreciated by staff and pet owners. He enjoyed playing music and singing, and was a serious runner.
Subject(s)
Veterinary Medicine , Veterinary Medicine/history , History, 21st Century , History, 20th Century , Humans , Veterinarians/psychology , Veterinarians/history , United KingdomABSTRACT
AIHA following allogeneic HSCT is appearing more frequently in the literature. It occurs as a result of donor cell-derived antibodies targeting donor red cell antigens. Little guidance exists on the management of such patients, particularly in the pediatric setting. First-line conventional treatment is corticosteroids and/or immunoglobulin therapy with monoclonal antibody therapy reserved for treatment failure. We report our experience of a child refractory to immunoglobulin and steroid therapy who required several infusions of rituximab and immunomodulatory therapy to obtain a clinically significant response.
