ABSTRACT
Estimar la incidencia, características anatomopatológicas, patrones de tratamiento y supervivencia-mortalidad del cáncer gástrico en la población de Segovia durante los años 2005-2008.MétodosEstudio descriptivo retrospectivo. Se incluyeron los 163 pacientes diagnosticados de cáncer gástrico en el Hospital General de Segovia en dicho periodo. Resultados Estimamos una incidencia de 25 casos/100.000 habitantes con una proporción varones/mujeres de 1,6:1 y una edad media de presentación de 72 años. El diagnóstico en estadios avanzados III y IV (64,5%), la alta frecuencia del carcinoma intestinal (56,4%) y el antro gástrico como localización más frecuente (48,8%), han sido las características del tumor más destacables. Al final del estudio un 54,2% de los pacientes habían fallecido, presentando una media de supervivencia global de 19 meses. La estadificación tumoral, el número de ganglios afectados y el tipo histológico difuso fueron los principales factores pronóstico desfavorables. A pesar de recibir tratamiento quirúrgico con intención curativa, el 63,2% de los tumores en estadios iniciales (I y II) presentaron recidiva durante el estudio. Conclusiones El riesgo de cáncer gástrico en Segovia es mayor en varones con edad en torno a los 70 años. Los estadios avanzados son la presentación más frecuente al diagnóstico y las recidivas en estadios iniciales son comunes, lo que dificulta las posibilidades de curación. Es necesario hacer un diagnóstico precoz del cáncer gástrico y mejorar los tratamientos (AU)
Objective: To estimate the incidence, pathological characteristics, treatment patterns, survival and mortality of gastric cancer in Segovia from 2005-2008.Methods: We conducted a retrospective, descriptive study of 163 patients diagnosed with gastric cancer at the Segovia General Hospital during the study period. Results: We estimated a gastric cancer incidence of 25 cases/100,000 inhabitants. The ratio of men to women was 1.6:1. The mean age was 72 years. The most important findings were diagnosis in stages III and IV (64.5%), the high frequency of intestinal carcinoma (56.4%) and the gastric antrum as the most frequent localization (48.8%). At the end of the study, 54.2%of patients had died and the median overall survival was 19 months. The main factors for an unfavorable prognosis were advanced tumoral stage (III and IV), the number of nodes involved, and diffuse histological type. Despite surgical treatment with curative intent, 63.2% of tumors at early stages (I and II) recurred during the study. Conclusions: The risk of gastric cancer in Segovia is higher in men aged over 70 years. Most tumors are diagnosed at advanced stages and recurrences are common, limiting the possibility of cure. Early diagnosis of this entity and improved treatments are required (AU)
Subject(s)
Humans , Stomach Neoplasms/epidemiology , Gastrectomy/statistics & numerical data , Adenocarcinoma/pathology , Antineoplastic Agents/therapeutic use , Neoplasm Recurrence, Local/epidemiologyABSTRACT
OBJECTIVE: To estimate the incidence, pathological characteristics, treatment patterns, survival and mortality of gastric cancer in Segovia from 2005-2008. METHODS: We conducted a retrospective, descriptive study of 163 patients diagnosed with gastric cancer at the Segovia General Hospital during the study period. RESULTS: We estimated a gastric cancer incidence of 25 cases/100,000 inhabitants. The ratio of men to women was 1.6:1. The mean age was 72 years. The most important findings were diagnosis in stages III and IV (64.5%), the high frequency of intestinal carcinoma (56.4%) and the gastric antrum as the most frequent localization (48.8%). At the end of the study, 54.2% of patients had died and the median overall survival was 19 months. The main factors for an unfavorable prognosis were advanced tumoral stage (III and IV), the number of nodes involved, and diffuse histological type. Despite surgical treatment with curative intent, 63.2% of tumors at early stages (I and II) recurred during the study. CONCLUSIONS: The risk of gastric cancer in Segovia is higher in men aged over 70 years. Most tumors are diagnosed at advanced stages and recurrences are common, limiting the possibility of cure. Early diagnosis of this entity and improved treatments are required.