Subject(s)
Amoxicillin-Potassium Clavulanate Combination/adverse effects , Anti-Allergic Agents/adverse effects , Cetirizine/adverse effects , Chemical and Drug Induced Liver Injury/diagnosis , Chemical and Drug Induced Liver Injury/etiology , beta-Lactamase Inhibitors/adverse effects , Adult , Biomarkers , Female , Humans , Liver Function Tests , Severity of Illness Index , UltrasonographyABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Amoxicillin-Potassium Clavulanate Combination/adverse effects , Anti-Allergic Agents/adverse effects , Cetirizine/adverse effects , Chemical and Drug Induced Liver Injury/diagnosis , Chemical and Drug Induced Liver Injury/etiology , beta-Lactamase Inhibitors/adverse effects , Biomarkers/blood , Liver Function Tests , Severity of Illness Index , UltrasonographyABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Chin/injuries , Primary Health Care , Anti-Bacterial Agents/therapeutic use , Erythema/diagnosis , Erythema/drug therapy , Superinfection/complications , Arthrodermataceae , Administration, Topical , Diagnosis, Differential , Superinfection/drug therapySubject(s)
Chin/injuries , Inflammation/diagnosis , Tinea/diagnosis , Diagnosis, Differential , Humans , Inflammation/pathology , Male , Middle Aged , Tinea/pathologyABSTRACT
The Drug Allergy Committee of the Spanish Society of Allergology and Clinical Immunology reviewed the allergenic potential of several substances of food origin that are found in the composition of some drugs. Despite recent legislation on labeling, many labels do not clearly state whether the drug contains raw material (active ingredients, excipient, or other manufacturing intermediate) with an origin in any of the substances in the list of the 14 groups of food allergens that are subject to mandatory declaration. The objective of legislation is that the drug package, the Summary of Product Characteristics, and the patient information leaflet clearly state the food content in order to improve the safety of allergic patients. Therefore, any food or allergen derivative that must be declared should be clearly stated on the drug label. Of all the evaluated products, egg and milk derivatives are the most frequently discussed in literature reviews. The natural or synthetic origin of potentially allergenic substances such as lysozyme, casein, lactose, albumin, phosphatide, and aromatic essences should be clearly stated. Providing this information has 2 clear advantages. First, allergic reactions to drugs in patients with food allergy could be avoided (if the substances have a natural origin). Second, prescription would improve by not restricting drugs containing synthetic substances (which do not usually induce allergic reactions).
Subject(s)
Drug Hypersensitivity/etiology , Food Additives/adverse effects , Food Hypersensitivity/etiology , Glucosamine/adverse effects , Humans , Lactose/adverse effects , Muramidase/adverse effects , Ovalbumin/adverse effects , Propofol/adverse effects , SpainSubject(s)
Cysticercosis/immunology , Adult , Antigens/immunology , Cross Reactions , Echinococcus/immunology , Female , Humans , Male , Middle Aged , Taenia/immunologyABSTRACT
Of the techniques which are usually used for the in vitro etiologic diagnosis of determined allergic processes, it is the RAST technique which is most widely used for determining specific antibodies of the IgE class. On the other hand, also of interest is the quantification of total IgE in these patients. We have studied 80 allergic and non allergic patients in order to evaluate the possible correlation between the Prick and the RAST tests applied to different allergens such house dust. Dermatophagoides pteronyssinus and Dermatophagoides farinae. The patients were distributed in four groups in relation to the clinical history and serum levels of total IgE, as follows: Group I: Patients with positive clinical history and increases levels of total IgE. Group II: patients with positive history and normal values of total IgE. Group III: patients with negative history and increased levels of serum IgE, and Group IV with non atopic subjects with normal values of IgE. The results show a high correlation between both tests for house dust mite allergens in the group I. The relation to inferior in the group II. As far as house dust is concerned, there is no correlation between the cutaneous test in the RAST test even in the group with positive clinical history. The data observed with house dust mites suggest a relation between the clinical history and the cutaneous test and also between the RAST and the levels of total serum IgE. These relations are not fund with house dust. It is discussed the validity and applications of both tests to the diagnosis of immediate hypersensitivity reactions to house dust mites and house dust.
