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1.
Cyberpsychol Behav Soc Netw ; 27(1): 28-36, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38197837

ABSTRACT

Immersive virtual reality (IVR) technology provides several educational affordances that make it a valuable tool for learning, especially from a constructivist learning perspective. Combined with the increasing availability of Metaverse social platforms, such as ENGAGE and AltSpace VR, where students and teachers can meet and work together, IVR may transform how students learn and interact with educational content. However, little is known about students' attitudes toward IVR in education. To address this gap, we surveyed 329 undergraduate students from different universities in Italy. We used the Unified Theory of Acceptance and Use of Technology (UTAUT) to predict students' intention to adopt IVR for learning. We further explored the role that different individual factors, including students' learning styles, affordances perceptions, and personal innovativeness, have on their attitudes toward IVR. A hierarchical multiple regression analysis revealed that the four constructs of the UTAUT, namely performance expectancy, effort expectancy, social influence, and facilitating conditions were the strongest predictors of students' intention to use IVR in education and that individual factors only had little impact on it. Based on these results, this study provides helpful indications for researchers and educators who wish to introduce IVR effectively in educational contexts. Given the new possibilities provided by Metaverse applications based on IVR technology for learning, it is indeed crucial to fully understand the attitudes different stakeholders in education have toward adopting this technology in educational contexts.


Subject(s)
Learning , Virtual Reality , Humans , Universities , Students , Intention
2.
Res Child Adolesc Psychopathol ; 52(3): 443-455, 2024 Mar.
Article in English | MEDLINE | ID: mdl-37947955

ABSTRACT

Early maladaptive traits are predictive of later borderline personality pathology (BPP), but little is known about their dynamic interplay over time. This is an important issue to address, however, as significant differences in the 'clinical weight' of various traits constituting the early BPP trait phenotype may inform the field on important target constructs from an early intervention perspective. Therefore, the current study aims to uncover the complex dependencies between BPP traits across the crucial developmental period of childhood and adolescence, by using longitudinal network analysis. Both between- and within-person networks were constructed to identify how early mother-reported borderline-related traits are connected across a timespan of six years (ntime 1 = 718, Mtime1 = 10.73 years, SDtime1 = 1.39, 55.1% girls). Overall, the temporal network suggested various trait interdependencies, with internalizing traits being particularly influential in the development of the BPP trait network structure. At the same time, externalizing traits likely inhibit the negative effects of these core traits. In addition, results also revealed that internalizing and externalizing clusters of early borderline-related traits are linked through emotional lability. Implications of these findings are discussed in view of the change mechanisms at play and potential targets for early intervention.


Subject(s)
Borderline Personality Disorder , Personality Disorders , Female , Humans , Adolescent , Male , Borderline Personality Disorder/psychology , Phenotype , Mood Disorders , Affective Symptoms
3.
J Psychiatr Res ; 167: 78-85, 2023 Oct 12.
Article in English | MEDLINE | ID: mdl-37856953

ABSTRACT

Using five independent non-clinical cross-cultural samples (total N = 3649; overall Mage = 29.31; 31% male and 69% female), this study explored the extent to which Dark Triad traits were indirectly associated with symptoms of psychopathology through mental toughness. Although Machiavellianism and psychopathy have not been studied extensively in this context, previous research (both cross-sectional and longitudinal) reports that grandiose narcissism increases mental toughness contributing indirectly to positive outcomes such as lower anxiety, stress, and depression. Accordingly, this study examined Machiavellianism, psychopathy, and narcissism in the context of mental toughness and psychopathology. A particular focus was placed on investigating negative relationships between grandiose narcissism and psychopathology. Participants completed self-report measures assessing the Dark Triad, mental toughness, and psychopathology. In all samples, grandiose narcissism exerted moderate negative, indirect associations with anxiety, stress, and depression through mental toughness. Relationships between Machiavellianism and psychopathy and psychopathology were generally weak and positive but varied across countries. Findings provided further cross-cultural support for a mediation model in which grandiose narcissism is related to higher mental toughness and lower psychopathology. Outcomes from this study indicate that exploration of the link between grandiose narcissism and resilience traits such as mental toughness can provide important conceptual insights into the adaptive properties of narcissism, and help to explain why grandiose narcissism is associated with a decrease in some psychopathological symptoms.

4.
Behav Ther ; 54(5): 719-733, 2023 09.
Article in English | MEDLINE | ID: mdl-37597953

ABSTRACT

Acceptance and Commitment Therapy (ACT) is purported to work via targeting six interrelated processes summarized as the Psychological Inflexibility/Psychological Flexibility (PI/PF) model. However, the theoretical structure and interconnections of this model have not been sufficiently explored. Lacking are examinations of the interrelations among its components. Network Analysis (NA) can model PI/PF as a system of interconnected variables. We aimed at exploring the role and associations of the PI/PF model's components using NA in two different samples and sets of scales, and compare its structure across sub-samples. Sample 1 consisted of 501 individuals, who completed an online battery of questionnaires including the Multidimensional Psychological Flexibility Inventory, and Sample 2 consisted of 428 people, who completed an online set of six ACT measures, each assessing a component of the PI/PF model. NA could not verify the six ACT dimensions as distinct components. Values and Committed Action components were found to be strongly associated and combined in a group in both sets of measures and samples. Interestingly, Acceptance and Defusion were not the most central components as purported in some ACT conceptualizations, whereas Self-as-Context had a key role on both sets of measures and its items were often merged with Present Moment Awareness items. No significant differences were found in the comparison of networks across different subsamples and sets of scales. After combining different sets of scales, the six ACT components could not be completely verified as distinct entities, which might reflect problems with the theoretical model, or with the scales used. All components had critical roles in the model, particularly Self-as-Context, which reflects the need to redirect research towards this understudied construct. Findings point towards considerations of a triflex instead of a hexaflex ACT model.


Subject(s)
Acceptance and Commitment Therapy , Humans , Models, Psychological
5.
Assessment ; : 10731911231183363, 2023 Jul 02.
Article in English | MEDLINE | ID: mdl-37394752

ABSTRACT

Cognitive reserve (CR) represents the adaptive response of the cognitive system responsible for preserving normal functioning in the face of brain damage. Experiential factors such as education, occupation, and leisure activities influence the development of CR. Theoretically, such factors build up from childhood and across adulthood. Thus, appropriate tools to define and measure CR as early as adolescence are essential to understand its developmental processes. To this aim, we introduce the construct of "Cognitive Reserve Potential" (CRP) and its corresponding index of experiential factors tailored to youth. We investigated prototypical youth exposures potentially associated with the lifelong development of CR (e.g., sport practice, musical experiences, cultural activities, and relationships with peers and family). Principal component analysis and confirmatory factor analysis identified and replicated the CRP factor structure on two independent samples of Italian students: N = 585 (295 F) and N = 351 (201 F), ages 11 to 20. CRP was associated mainly with family socio-cultural status (i.e., socioeconomic status [SES], Home Possessions, and Books at Home). Results confirmed the strength of the factorial model and warranted the proposal of the CRP-questionnaire as an innovative tool for understanding CR evolutionary dynamics.

7.
Phys Biol ; 20(5)2023 07 10.
Article in English | MEDLINE | ID: mdl-37364583

ABSTRACT

Correlation analysis and its close variant principal component analysis are tools widely applied to predict the biological functions of macromolecules in terms of the relationship between fluctuation dynamics and structural properties. However, since this kind of analysis does not necessarily imply causation links among the elements of the system, its results run the risk of being biologically misinterpreted. By using as a benchmark the structure of ubiquitin, we report a critical comparison of correlation-based analysis with the analysis performed using two other indicators, response function and transfer entropy, that quantify the causal dependence. The use of ubiquitin stems from its simple structure and from recent experimental evidence of an allosteric control of its binding to target substrates. We discuss the ability of correlation, response and transfer-entropy analysis in detecting the role of the residues involved in the allosteric mechanism of ubiquitin as deduced by experiments. To maintain the comparison as much as free from the complexity of the modeling approach and the quality of time series, we describe the fluctuations of ubiquitin native state by the Gaussian network model which, being fully solvable, allows one to derive analytical expressions of the observables of interest. Our comparison suggests that a good strategy consists in combining correlation, response and transfer entropy, such that the preliminary information extracted from correlation analysis is validated by the two other indicators in order to discard those spurious correlations not associated with true causal dependencies.


Subject(s)
Molecular Dynamics Simulation , Ubiquitin , Ubiquitin/chemistry , Entropy , Allosteric Regulation
8.
Am J Phys Med Rehabil ; 102(7): 571-576, 2023 07 01.
Article in English | MEDLINE | ID: mdl-36882316

ABSTRACT

OBJECTIVE: Chronic low back pain (CLBP) is the leading cause of disability worldwide, and several factors have been proposed as potential causes or cofactors. The aim of this study was to explore their direct and indirect relations to understand CLBP and identify relevant rehabilitation targets. METHODS: A total of 119 patients with CLBP and 117 chronic pain-free individuals were assessed. A network analysis approach was used to explore the complexity of CLBP by assessing the relations between pain intensity, disability, functionality (physical, social, and psychological), age, body mass index, and education level. RESULTS: The network analysis revealed the independence of pain and disability related to CLBP from age, sex, and body mass index. Crucially, pain intensity and disability are directly and strongly connected in chronic pain-free individuals, but not in patients with CLBP. Psychosocial functioning is related to pain intensity and disability indirectly through the mediation of one's general health perception and perceived physical functionality. CONCLUSION: Clinicians should pay more attention to perceived physical functionality and psychosocial factors as they are tightly linked to CLBP. Indeed, pain intensity seems a suboptimal rehabilitation target. This study suggests that a biopsychosocial approach is much needed to investigate CLBP, but it also warns against overestimating the direct impact of each potential contributor. TO CLAIM CME CREDITS: Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME. CME OBJECTIVES: Upon completion of this article, the reader should be able to: (1) Recognize the relation of pain intensity, disability, and loss of function in patients with CLBP; (2) Determine the impact of the most common biological and psychosocial factors in addressing the assessment of chronic back pain patients; and (3) Enhance confidence in selecting the relevant outcomes for the assessment of patients with CLBP following a multidimensional assessment. LEVEL: Advanced. ACCREDITATION: The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™ . Physicians should only claim credit commensurate with the extent of their participation in the activity.


Subject(s)
Chronic Pain , Disabled Persons , Low Back Pain , Humans , Physical Therapy Modalities , Disabled Persons/psychology , Pain Measurement
9.
Assessment ; 30(8): 2510-2532, 2023 12.
Article in English | MEDLINE | ID: mdl-36794796

ABSTRACT

The HEXACO model divides the space of personality into six main dimensions: Honesty-Humility, Emotionality, eXtraversion, Agreeableness (vs. anger), Conscientiousness, and Openness to Experience. Despite the lexical foundation, no validated adjective-based instruments are available yet. This contribution describes the newly developed HEXACO Adjective Scales (HAS), a 60 adjectives instrument to measure the six main personality dimensions. Study 1 (N=368) proceeds to the first pruning of a large set of adjectives to identify potential markers. Study 2 (N=811) delineates the final list of 60 adjectives and provides benchmarks for the new scales' internal consistency, convergent/discriminant, and criterion validity. Study 3 (N=411) confirms the HAS factorial structure, internal consistency, and criterion validity. The study also provides evidence of temporal stability (test-retest reliability) and convergence between raters (peer/self-evaluation). The HAS shows excellent psychometric properties and constitutes a valuable tool for assessing the HEXACO personality dimensions using adjectives.


Subject(s)
Personality Disorders , Personality , Humans , Psychometrics , Reproducibility of Results , Personality Inventory
10.
Int J Lang Commun Disord ; 58(4): 1182-1190, 2023.
Article in English | MEDLINE | ID: mdl-36726040

ABSTRACT

BACKGROUND: The comprehension profile of people with agrammatism is a debated topic. Syntactic complexity and cognitive resources, in particular phonological short-term memory (pSTM), are considered as crucial components by different interpretative accounts. AIM: To investigate the interaction of syntactic complexity and of pSTM in sentence comprehension in a group of persons with aphasia with and without agrammatism. METHODS & PROCEDURES: A cohort of 30 participants presenting with aphasia was assessed for syntactic comprehension and for pSTM. A total of 15 presented with agrammatism and 15 had fluent aphasia. OUTCOMES & RESULTS: Linear nested mixed-model analyses revealed a significant interaction between sentence type and pSTM. In particular, participants with lower pSTM scores showed a reduced comprehension of centre-embedded object relatives and long coordinated sentences. Moreover, a significant interaction was found between sentence type and agrammatism, with a lower performance for passives within the agrammatic group. CONCLUSIONS & IMPLICATIONS: These results confirm that pSTM is involved in the comprehension of complex structures with an important computational load, in particular coordinated sentences, and long-distance filler gap dependencies. On the contrary, the specific deficit of the agrammatic group with passives is a pure syntactic deficit, with no involvement of pSTM.


Subject(s)
Aphasia, Broca , Comprehension , Memory, Short-Term , Humans , Aphasia, Broca/psychology , Language , Semantics
11.
Sci Rep ; 13(1): 1703, 2023 Jan 30.
Article in English | MEDLINE | ID: mdl-36717666

ABSTRACT

The diffusion-weighted NMR signal acquired using Pulse Field Gradient (PFG) techniques, allows for extrapolating microstructural information from porous materials and biological tissues. In recent years there has been a multiplication of diffusion models expressed by parametric functions to fit the experimental data. However, clear-cut criteria for the model selection are lacking. In this paper, we develop a theoretical framework for the interpretation of NMR attenuation signals in the case of Gaussian systems with stationary increments. The full expression of the Stejskal-Tanner formula for normal diffusing systems is devised, together with its extension to the domain of anomalous diffusion. The range of applicability of the relevant parametric functions to fit the PFG data can be fully determined by means of appropriate checks to ascertain the correctness of the fit. Furthermore, the exact expression for diffusion weighted NMR signals pertaining to Brownian yet non-Gaussian processes is also derived, accompanied by the proper check to establish its contextual relevance. The analysis provided is particularly useful in the context of medical MRI and clinical practise where the hardware limitations do not allow the use of narrow pulse gradients.

12.
J Pers ; 91(4): 977-991, 2023 08.
Article in English | MEDLINE | ID: mdl-35037250

ABSTRACT

OBJECTIVE: Personality involves both trait and state components, personal goals serving a crucial regulatory function for the expression of personality states. The present study investigates the dynamic interplay between conscientiousness-related goals, conscientious personality states, and trait conscientiousness. METHOD: A sample of 244 community participants responded to a baseline survey (T1), a 5-times-a-day Ecological Momentary Assessment (EMA) for 15 days, and a post-EMA survey (T2). RESULTS: Pre-registered multilevel analyses indicated significant contemporaneous positive and negative associations between momentary conscientious and unconscientious goals and state conscientiousness, respectively. Cross-lagged associations also emerged, with goals predicting future states of conscientiousness. A latent growth model was fitted on a subsample of participants (N = 159). Results indicated that change in trait conscientiousness from T1 to T2 was explained by growth in conscientiousness-related goals during the EMA phase, with a mediating effect of growth in state conscientiousness. CONCLUSIONS: Overall, the results corroborate the importance of goals for modeling contemporaneous and cross-lagged personality dynamics, both in short and longer timeframes.


Subject(s)
Goals , Personality , Humans , Surveys and Questionnaires , Personality Disorders , Ecological Momentary Assessment
13.
Assessment ; 30(5): 1391-1406, 2023 07.
Article in English | MEDLINE | ID: mdl-35699415

ABSTRACT

The Pathological Narcissism Inventory (PNI) is extensively used in recent empirical literature on pathological narcissism. However, most studies using the PNI are community-based, and no studies have used the PNI to investigate narcissistic presentations in personality disordered patients. This study investigates measurement invariance of the PNI in community participants and patients with personality disorders, and examines differences of narcissistic presentations in these samples through a multimethod approach. Results show that the PNI can be used reliably to measure and compare traits of pathological narcissism in community participants and patients with personality disorders. Personality disordered patients show higher traits reflecting vulnerable narcissism and overt manifestations of grandiose narcissism, compared with controls. Finally, network analysis indicates that traits of grandiose fantasies and entitlement rage have a central role in defining manifestations of PNI pathological narcissism, regardless of the presence of an underlying personality disorder. Research and clinical implications are discussed.


Subject(s)
Narcissistic Personality Disorder , Personality Inventory , Residence Characteristics , Narcissism , Humans , Male , Female , Adolescent , Young Adult , Adult , Middle Aged , Aged , Personality Inventory/standards , Narcissistic Personality Disorder/diagnosis , Narcissistic Personality Disorder/psychology , Anger , Fantasy , Models, Psychological , Personality Disorders/diagnosis , Personality Disorders/psychology , Case-Control Studies
14.
Sci Rep ; 12(1): 22102, 2022 12 21.
Article in English | MEDLINE | ID: mdl-36543793

ABSTRACT

People cooperate every day in ways that range from largescale contributions that mitigate climate change to simple actions such as leaving another individual with choice - known as social mindfulness. It is not yet clear whether and how these complex and more simple forms of cooperation relate. Prior work has found that countries with individuals who made more socially mindful choices were linked to a higher country environmental performance - a proxy for complex cooperation. Here we replicated this initial finding in 41 samples around the world, demonstrating the robustness of the association between social mindfulness and environmental performance, and substantially built on it to show this relationship extended to a wide range of complex cooperative indices, tied closely to many current societal issues. We found that greater social mindfulness expressed by an individual was related to living in countries with more social capital, more community participation and reduced prejudice towards immigrants. Our findings speak to the symbiotic relationship between simple and more complex forms of cooperation in societies.


Subject(s)
Emigrants and Immigrants , Mindfulness , Humans
15.
Front Hum Neurosci ; 16: 920558, 2022.
Article in English | MEDLINE | ID: mdl-35814951

ABSTRACT

Behavioral effects of non-invasive brain stimulation techniques (NIBS) can dramatically change as a function of different factors (e.g., stimulation intensity, timing of stimulation). In this framework, lately there has been a growing interest toward the importance of considering the inter-individual differences in baseline performance and how they are related with behavioral NIBS effects. However, assessing how baseline performance level is associated with behavioral effects of brain stimulation techniques raises up crucial methodological issues. How can we test whether the performance at baseline is predictive of the effects of NIBS, when NIBS effects themselves are estimated with reference to baseline performance? In this perspective article, we discuss the limitations connected to widely used strategies for the analysis of the association between baseline value and NIBS effects, and review solutions to properly address this type of question.

16.
Br J Educ Psychol ; 92(4): 1597-1620, 2022 Dec.
Article in English | MEDLINE | ID: mdl-35698429

ABSTRACT

BACKGROUND: Spatial ability (SA) was shown to be important for success in different fields, including STEM. Recent research suggested that SA is a unitary construct, rather than a set of related skills. However, it is not clear how individual differences in different facets of SA emerge, and how they relate to variance in general cognitive ability. AIMS: The aim of the present study was threefold: 1) to examine the structure of SA testing nine theoretical models; 2) to explore the relation between 16 different facets of SA with general cognitive ability; and 3) to identify central facet(s) within the network of SA - with most links and/or strongest links to other facets. SAMPLE: The study participants were 958 university students from Russia. METHODS: The study used a comprehensive battery of 16 SA tests and a verbal ability measure. RESULTS: Results supported previous research, suggesting moderate overlap between all SA facets. Factor analysis suggested several potential structures, with similar fit indices for five different theoretically driven models, including split into small- and large scale; partially independent manipulation, visualization and navigation facets. Confirmatory factor analysis, mediation and network analyses showed spatial ability being largely independent from verbal ability. In addition, network analysis showed that navigation according to directions is in the centre of the network, potentially linking all SA facets. CONCLUSION: The results have potential implications for identifying the best targets for SA interventions. The next step in research is conducting experimental studies to evaluate effectiveness of interventions targeting navigation in comparison with other facets of SA.


Subject(s)
Spatial Navigation , Humans , Factor Analysis, Statistical , Cognition
17.
Sci Rep ; 12(1): 1514, 2022 02 17.
Article in English | MEDLINE | ID: mdl-35177625

ABSTRACT

Happiness is a valuable experience, and societies want their citizens to be happy. Although this societal commitment seems laudable, overly emphasizing positivity (versus negativity) may create an unattainable emotion norm that ironically compromises individual well-being. In this multi-national study (40 countries; 7443 participants), we investigate how societal pressure to be happy and not sad predicts emotional, cognitive and clinical indicators of well-being around the world, and examine how these relations differ as a function of countries' national happiness levels (collected from the World Happiness Report). Although detrimental well-being associations manifest for an average country, the strength of these relations varies across countries. People's felt societal pressure to be happy and not sad is particularly linked to poor well-being in countries with a higher World Happiness Index. Although the cross-sectional nature of our work prohibits causal conclusions, our findings highlight the correlational link between social emotion valuation and individual well-being, and suggest that high national happiness levels may have downsides for some.


Subject(s)
Happiness , Peer Influence , Perception , Cross-Sectional Studies , Humans
18.
Acta Psychol (Amst) ; 224: 103529, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35151956

ABSTRACT

The first Italian lockdown during COVID-19 pandemic constituted an example of strong situation. Under this context, we investigated associations of HEXACO personality with COVID-19 mitigation behaviors (self-reported hygiene, distancing, going out). We tested unique associations through regularized regressions and out-of-sample prediction after establishing the best level of analysis (HEXACO traits, facets, items). Personality always explained out-of-sample variance over and above demographics, COVID-related knowledge, concern, impacts, and goals. Hygiene and distancing were best predicted by HEXACO traits, whereas facets constituted the best level for the prediction of going out. In general, honesty-humility (trait or facets) was the clearest predictor of safer behaviors. Results corroborate the relevance of personality even in strong situations, as well as its importance for COVID-19 mitigation.


Subject(s)
COVID-19 , Communicable Disease Control , Humans , Pandemics , Personality , SARS-CoV-2
19.
J Pers Assess ; 104(3): 335-346, 2022.
Article in English | MEDLINE | ID: mdl-34282977

ABSTRACT

This study presents the adaptation to the Italian context of the Relationship Profile Test (RPT; Bornstein & Languirand), a self-report measure of Destructive Overdependence (DO), Dysfunctional Detachment (DD), and Healthy Dependency (HD). The RPT was administered to a community sample of 661 nonclinical Italian adults together with the Attachment Style Questionnaire, the Relational-Interdependent Self-Construal Scale, the Rosenberg Self-Esteem Scale, the Self-Compassion Scale, the Positive Affect-Negative Affect Scale, and the Toronto Alexithymia Scale. A randomly selected subset of participants (n = 67) completed the RPT again approximately 5 months after the first administration. The factor structure of the RPT obtained in the main sample was compared with that obtained in a sample of 603 adult participants from the US and was found to be similar. Internal consistency for DO, DD, and HD scores in the Italian sample fell between the acceptable to good range, and test-retest reliability coefficients were all above .70. The three scales yielded the expected pattern of correlations with theoretically related constructs, documenting good criterion validity. Findings are discussed in light of the literature on the RPT as a measure of interpersonal dependency and detachment. Suggestions for future research are offered.


Subject(s)
Cross-Cultural Comparison , Interpersonal Relations , Adult , Health Status , Humans , Italy , Psychometrics , Reproducibility of Results , Surveys and Questionnaires
20.
Front Neurol ; 12: 794471, 2021.
Article in English | MEDLINE | ID: mdl-34938268

ABSTRACT

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mainly colonizes nasopharynx. In upper airways acute infections, e.g., the common cold, saline nasal irrigations have a significant efficacy in reducing symptoms. The present study aimed to test the efficacy of nasal lavages in upper airways symptoms of Coronavirus Disease 2019 (COVID-19). Methods: A series of consecutive adult subjects who tested positive for SARS-CoV-2 from December 2020 to February 2021 performed daily nasal lavages with saline solution (Lavonase®-Purling, Lugo di Romagna, Italy) for 12 days, starting on the day after the SARS-CoV-2 positive swab. A control group included a historical series of patients who were infected in February-March 2020 and who did not perform lavages. An ad hoc questionnaire regarding symptoms was administered to each subjects at base-line and 10 days after diagnosis (i.e., on the same day of the control swab) in both cases and controls. Results: A total of 140 subjects were enrolled. 68 participants in the treatment group and 72 in the control group were included. 90% of respondents declared the lavages were simple to use and 70% declared they were satisfied. Symptoms of blocked nose, runny nose, or sneezing decreased by an average of 24.7% after the treatment. Blocked nose and sneezing increased in the same period of time in the control group. Ears and eyes symptoms, anosmia/ageusia symptoms, and infection duration (10.53 days in the treatment group and 10.48 days in the control group) didn't vary significantly among the two groups. Conclusion: Nasal lavages resulted to significantly decrease nasal symptoms in newly diagnosed SARS-CoV-2 patients. These devices proved to be well-tolerated and easy to be used. Further studies on a larger number of subjects are needed in order to possibly confirm these preliminary results.

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