1.
Clin Infect Dis
; 23(6): 1326-7, 1996 Dec.
Article
in English
| MEDLINE
| ID: mdl-8953089
Subject(s)
Aspergillosis/complications , Aspergillus fumigatus/isolation & purification , Fungemia/complications , Hepatoblastoma/complications , Aspergillosis/drug therapy , Aspergillosis/microbiology , Aspergillosis/physiopathology , Fungemia/drug therapy , Fungemia/microbiology , Fungemia/physiopathology , Hepatoblastoma/microbiology , Humans , Infant , Male
2.
Arch Dis Child
; 70(6): 484-7, 1994 Jun.
Article
in English
| MEDLINE
| ID: mdl-8048816
ABSTRACT
The feasibility and efficacy of a once daily antibiotic regimen were assessed in children with malignant tumours. Over a 44 month period, 296 febrile episodes were treated with a regimen of once daily ceftriaxone-amikacin (and teicoplanin or vancomycin if the patient had a central line). The treatment was successful in 272 (92%) episodes without modification of the antibiotic regimen, and only one patient died of uncontrolled sepsis. A once daily antibiotic regimen is therefore feasible and worthwhile in the treatment of febrile episodes in children with cancer.