Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Therapie ; 70(6): 541-4, 2015.
Article in French | MEDLINE | ID: mdl-26238127

ABSTRACT

A 62-year-old woman treated with fluvastatin experienced three separate thrombocytopenic illnesses, severe on two occasions associated with nadir platelet count of 57 000/µL and 75 000/µL. The hospital pharmacist replaced fluvastatin by pravastatin during three stays. Platelet count has increased some days after this substitution. These results suggest that fluvastatin could be involved in these thrombocytopenic episodes.


Subject(s)
Fatty Acids, Monounsaturated/adverse effects , Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects , Indoles/adverse effects , Thrombocytopenia/chemically induced , Acetaminophen/administration & dosage , Acetaminophen/therapeutic use , Binding, Competitive , Comorbidity , Cytochrome P-450 CYP2C9/metabolism , Cytochrome P-450 CYP2C9 Inhibitors/pharmacokinetics , Drug Substitution , Drug Synergism , Fatty Acids, Monounsaturated/administration & dosage , Fatty Acids, Monounsaturated/pharmacokinetics , Fatty Acids, Monounsaturated/therapeutic use , Female , Fluvastatin , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacokinetics , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Inactivation, Metabolic/drug effects , Indoles/administration & dosage , Indoles/pharmacokinetics , Indoles/therapeutic use , Middle Aged , Pravastatin/therapeutic use , Recurrence , Valproic Acid/administration & dosage , Valproic Acid/adverse effects , Valproic Acid/pharmacokinetics , Valproic Acid/therapeutic use
SELECTION OF CITATIONS
SEARCH DETAIL