[A case of pulmonary aspergillosis effectively treated with itraconazole. Possible interaction of the antimycotic agent with hydroquinidine]. / Un caso di aspergillosi polmonare trattato efficacemente con itraconazolo. Possibile interferenza dell'antimicotico con la idrochinidina.

This study describes a case of pulmonary aspergilloma in a neutropenic patient affected with myelodysplastic syndrome. It reports the therapeutic efficacy of itraconazole, emphasizing in particular the possible interaction with quinidine, with QT prolongation--at ECG--disappeared after quinidine withdrawal.

HIV-related thrombotic thrombocytopenic purpura (TTP) as first clinical manifestation of infection.

A case of thrombotic thrombocytopenic purpura (TTP) in a 40-year-old bisexual man unaware of being HIV positive is reported. The hematologic syndrome represented the first clinical manifestation of this viral infection. The clinical picture, characterized by severe hemolytic microangiopathic anemia, thrombocytopenia, fluctuating neurologic abnormalities and fever, quickly improved after plasma exchange and corticosteroid therapy. Two blood tests showed severe depletion of the CD4+ lymphocyte count and HIV antigenemia was positive. This case represents a clinical epiphenomenon of HIV infection in an advanced phase. According to recent CDC criteria the patient should be considered in AIDS. Antiretroviral treatment was started and after nine months of follow-up there has been no relapse.

[A case of intestinal schistosomiasis with hepatic involvement: interdisciplinary diagnostic approach and peculiarity of the echographic and histologic findings]. / Un caso di schistosomiasi intestinale con interessamento epatico: approccio diagnostico interdisciplinare e peculiarità dei reperti ecografico e istologico.

We report a case of intestinal schistosomiasis; secondary hepatic involvement is particularly described, with a very distinctive ecographic feature of portal hypertension and a bioptic picture stressing a granulomatous periportal inflammation. In the work we emphasize the importance of a multidisciplinary approach (physicians working in the fields of internal medicine, infectious disease, gastrointestinal diseases, radiologist, pathologist) in the course of diagnostic investigation. Finally, we confirm the effectiveness of praziquantel against Schistosoma mansoni.

[Incidence of oxyuriasis in a schoolchild population in Milan, with socio-economic correlations. Verification of the therapeutic effectiveness of pyrantel pamoate]. / Incidenza della ossiuriasi nella popolazione scolastica infantile milanese con correlazioni socio-economiche. Verifica della efficacia terapeutica del "pirantel pamoato".

440 children aged between 3 and 5 were examined for Oxyuriasis in three schools of Milan during three different days. 31% of the children resulted parasited by Enterobius vermicularis: a clear correlation between parasitosis and socio-economic condition has been demonstrated. Treatment with "pirantel pamoate" has been proved effective in 88% of the cases.