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2.
Arch. Soc. Esp. Oftalmol ; 93(12): 606-609, dic. 2018. ilus
Article in Spanish | IBECS | ID: ibc-175155

ABSTRACT

CASO CLÍNICO: Un varón de 70 años, procedente de Sicilia, acude con una masa palpebral bilateral con afectación tarsal conjuntival, que resultó ser un sarcoma de Kaposi al examen histológico. Se demostró afectación cutánea y pulmonar por el sarcoma de Kaposi. El paciente no tenía un diagnóstico previo de infección por el virus de la inmunodeficiencia humana. Este caso fue tratado con éxito tras 5 ciclos de quimioterapia con doxorrubicina liposomal, con resolución de las lesiones palpebrales, cutáneas y pulmonares. Conclusiones: La localización en el párpado es una posible manifestación inicial, aunque rara, del sarcoma de Kaposi en personas de edad avanzada negativos para el virus de la inmunodeficiencia humana. La doxorrubicina liposomal es un tratamiento seguro y efectivo


CASE REPORT: We report a case of 70-year-old male from Sicily, who presented with a bilateral eyelid mass involving the tarsal conjunctiva, found to be Kaposi's sarcoma on histologic examination. Cutaneous and pulmonary Kaposi's sarcoma involvement was documented. The patient had no prior diagnosis of human immunodeficiency virus infection. This case was managed successfully after the completion of five cycles of chemotherapy with liposomal doxorubicin, and his eyelid, skin and pulmonary lesions disappeared. CONCLUSIONS: Location in the eyelid is a possible, though rare, initial solitary manifestation of Kaposi's sarcoma in elderly HIV-negative patients. Liposomal doxorubicin is a safe and effective treatment


Subject(s)
Humans , Male , Aged , Sarcoma, Kaposi/complications , Eyelid Diseases/pathology , Doxorubicin/therapeutic use , Visual Acuity , Biopsy , HIV Seronegativity , Conjunctiva/pathology , Eyelids/pathology , Diagnosis, Differential , Immunohistochemistry , Enzyme-Linked Immunosorbent Assay , Blotting, Western , Sarcoma, Kaposi/diagnostic imaging , Sarcoma, Kaposi/therapy
3.
Arch Soc Esp Oftalmol (Engl Ed) ; 93(12): 606-609, 2018 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-30055902

ABSTRACT

CASE REPORT: We report a case of 70-year-old male from Sicily, who presented with a bilateral eyelid mass involving the tarsal conjunctiva, found to be Kaposi's sarcoma on histologic examination. Cutaneous and pulmonary Kaposi's sarcoma involvement was documented. The patient had no prior diagnosis of human immunodeficiency virus infection. This case was managed successfully after the completion of five cycles of chemotherapy with liposomal doxorubicin, and his eyelid, skin and pulmonary lesions disappeared. CONCLUSIONS: Location in the eyelid is a possible, though rare, initial solitary manifestation of Kaposi's sarcoma in elderly HIV-negative patients. Liposomal doxorubicin is a safe and effective treatment.


Subject(s)
Antibiotics, Antineoplastic/therapeutic use , Doxorubicin/analogs & derivatives , Eyelid Neoplasms/drug therapy , Neoplasms, Multiple Primary/drug therapy , Sarcoma, Kaposi/drug therapy , Aged , Doxorubicin/therapeutic use , Eyelid Neoplasms/diagnostic imaging , HIV Seronegativity , Humans , Male , Neoplasms, Multiple Primary/diagnostic imaging , Polyethylene Glycols/therapeutic use , Remission Induction , Sarcoma, Kaposi/diagnostic imaging , Tomography, X-Ray Computed
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