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1.
Science ; 384(6701): 1160-1161, 2024 Jun 14.
Article in English | MEDLINE | ID: mdl-38870299

ABSTRACT

Ancient DNA shows continuity between living and ancient Maya communities.


Subject(s)
Ceremonial Behavior , Civilization , DNA, Ancient , Twins , Female , Humans , Male , History, Ancient , Twins/history , Child , Civilization/history
2.
Science ; 384(6691): 13-14, 2024 Apr 05.
Article in English | MEDLINE | ID: mdl-38574124

ABSTRACT

Complex tools from 300,000-year-old deposit at Schöningen in Germany point to a "wood age".


Subject(s)
Neanderthals , Wood , Animals , Archaeology , Germany , Neanderthals/psychology
3.
Science ; 383(6682): 468-469, 2024 Feb 02.
Article in English | MEDLINE | ID: mdl-38301014

ABSTRACT

Moderns made mysterious ice age artifacts-implying overlap with Neanderthals.


Subject(s)
Neanderthals , Animals , Humans , Europe , Fossils
4.
Science ; 383(6679): 138-139, 2024 01 12.
Article in English | MEDLINE | ID: mdl-38207026

ABSTRACT

Among Europeans, risk of multiple sclerosis rises with genes from Bronze Age Yamnaya herders.


Subject(s)
DNA, Ancient , Multiple Sclerosis , Humans , Europe/epidemiology , Genome, Human , Multiple Sclerosis/epidemiology , Multiple Sclerosis/genetics , Multiple Sclerosis/history
5.
Science ; 382(6674): 982-983, 2023 12.
Article in English | MEDLINE | ID: mdl-38033060

ABSTRACT

8000 years ago-long before farming arrived-people in Siberia built defensive structures.


Subject(s)
Hunting , Humans , Farms/history , Siberia , Hunting/history
6.
Toxins (Basel) ; 15(10)2023 10 18.
Article in English | MEDLINE | ID: mdl-37888650

ABSTRACT

Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum neurotoxins. This review summarizes the literature on the safety of HSA. Beyond decades of safe use, the largest clinical dataset of HSA safety is a large meta-analysis of HSA supplier data, which found only an extremely remote risk of serious adverse events across millions of doses of therapeutic concentrations of HSA. There is a paucity of literature identifying HSA-specific adverse events when used as a stabilizer/excipient; however, studies of HSA-containing botulinum neurotoxins (BoNTs) suggest that adverse events are not related to HSA. Polysorbates, which are synthetically produced and not physiologically inert, are contained in pending or new-to-market BoNT formulations. In contrast to HSA, evidence exists to suggest that polysorbates (particularly PS20/PS80) can cause serious adverse events (e.g., hypersensitivity, anaphylaxis, and immunogenicity).


Subject(s)
Botulinum Toxins, Type A , Botulinum Toxins , Humans , Botulinum Toxins/adverse effects , Serum Albumin, Human/adverse effects , Excipients , Polysorbates , Botulinum Toxins, Type A/adverse effects
7.
Science ; 382(6666): 24-27, 2023 10 06.
Article in English | MEDLINE | ID: mdl-37797011

ABSTRACT

Giant family trees based on ancient DNA from thousands of people are revealing prehistoric politics and social structure.

8.
Science ; 381(6657): 472-477, 2023 Aug 04.
Article in English | MEDLINE | ID: mdl-37535720

ABSTRACT

DNA from enslaved Black workers at a 19th century iron forge links them to living descendants. But the research swirls with ethical questions.

9.
Science ; 379(6635): 865-866, 2023 03 03.
Article in English | MEDLINE | ID: mdl-36862777

ABSTRACT

Genes reveal striking diversity within similar ice age cultures.


Subject(s)
Cultural Diversity , DNA, Ancient , Europe , Humans
10.
Science ; 379(6639): 1288-1293, 2023 03 31.
Article in English | MEDLINE | ID: mdl-36996207

ABSTRACT

After the Spanish conquest, horses transformed Native American tribes much earlier than historians thought.


Subject(s)
American Indian or Alaska Native , Horses , Human-Animal Interaction , Animals , North America , Spain , Archaeology , Humans
11.
Science ; 379(6639): 1284-1285, 2023 03 31.
Article in English | MEDLINE | ID: mdl-36996223

ABSTRACT

Ancient DNA reflects foreign influx to Swahili coast, but its culture is largely local.

12.
Science ; 379(6631): 424-425, 2023 02 03.
Article in English | MEDLINE | ID: mdl-36730400

ABSTRACT

Analysis reveals the chemicals applied to corpses in a 2700-year-old mummification workshop.


Subject(s)
Mummies , Humans , Cadaver , Egypt , History, Ancient , Mummies/history
13.
Science ; 379(6631): 428, 2023 02 03.
Article in English | MEDLINE | ID: mdl-36730401

ABSTRACT

Meat from the butchered beasts would have fed hundreds.


Subject(s)
Feeding Behavior , Group Processes , Hunting , Meat , Neanderthals , Animals , Eating , Meat/history , Neanderthals/psychology , Hunting/history , Elephants
14.
Science ; 378(6623): 940-943, 2022 12 02.
Article in English | MEDLINE | ID: mdl-36454815

ABSTRACT

DNA from a medieval German cemetery opens a window on the history of today's largest Jewish population.


Subject(s)
Jews , Jews/genetics , Population/genetics , Germany , Cemeteries/history , DNA, Ancient , Humans
15.
Science ; 378(6620): 587, 2022 11 11.
Article in English | MEDLINE | ID: mdl-36356150

ABSTRACT

Body's survival without lucky accidents of climate suggests more ice mummies await.


Subject(s)
Climate , Ice , Mummies , Archaeology , Cadaver
16.
Science ; 378(6615): 12, 2022 10 07.
Article in English | MEDLINE | ID: mdl-36201580

ABSTRACT

By sequencing ancient hominins' DNA, Pääbo explored "what makes us uniquely human".


Subject(s)
DNA, Ancient , Hominidae , Animals , Hominidae/genetics , Humans , Nobel Prize
17.
Science ; 377(6613): 1371, 2022 09 23.
Article in English | MEDLINE | ID: mdl-36137029

ABSTRACT

Genetic study of burials suggests whole families migrated to the island in the first millennium C.E.


Subject(s)
Emigration and Immigration , White People , Burial , DNA, Ancient , Emigration and Immigration/history , England , History, Ancient , Humans , Sequence Analysis, DNA , White People/genetics
18.
Science ; 377(6609): 908-909, 2022 08 26.
Article in English | MEDLINE | ID: mdl-36007048

ABSTRACT

Studies seek clues to origins of farming, early languages.


Subject(s)
Civilization , DNA, Ancient , Farms , Language , Civilization/history , Farms/history , History, Ancient , Humans , Language/history , Middle East
19.
Science ; 375(6587): 1330, 2022 03 25.
Article in English | MEDLINE | ID: mdl-35324281

ABSTRACT

Russian disinformation campaign targets routine research on bat parasites.

20.
Science ; 375(6586): 1210-1211, 2022 Mar 18.
Article in English | MEDLINE | ID: mdl-35298247

ABSTRACT

Researchers hide ancient weapons and bat skulls, upload data as bombs fall.

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