ABSTRACT
A 6-year-old castrated Goldendoodle dog was presented for left-sided lameness of 3 weeks' duration. Focal, moderate to marked increased 99m Tc-methylene diphosphonate (99m Tc-MDP) uptake was detected in the right caudal lung lobe, caudal angle of the left scapula, and the distal aspect of the left femur with whole body bone phase scintigraphy. Radiographs identified a well-circumscribed, oval-shaped soft tissue opaque mass in the right caudal lung lobe; a suspect oval-shaped osteolytic lesion in the proximal third of the left scapula; and an osteolytic lesion in the distal aspect of the left femur. Metastatic pilomatricoma was confirmed histologically at all three sites.
Subject(s)
Bone Neoplasms/veterinary , Dog Diseases/diagnostic imaging , Lung Neoplasms/veterinary , Pilomatrixoma/veterinary , Skin Neoplasms/veterinary , Animals , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/secondary , Dog Diseases/pathology , Dogs , Fatal Outcome , Femur/diagnostic imaging , Femur/pathology , Hair Diseases/pathology , Hair Diseases/veterinary , Lameness, Animal/diagnostic imaging , Lameness, Animal/pathology , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/secondary , Male , Pilomatrixoma/secondary , Radionuclide Imaging , Scapula/diagnostic imaging , Scapula/pathology , Skin Neoplasms/pathology , Technetium Tc 99m MedronateABSTRACT
A 5-year-old spayed female Shih Tzu was referred for evaluation of a nasal transitional carcinoma. A total lifetime dose of 117 Gy was delivered to the intranasal mass in three courses over nearly 2 years using fractionated intensity modulated radiation therapy (IMRT) to spare normal tissues. Clinically significant late normal tissue side effects were limited to bilaterally diminished tear production. The patient died of metastatic disease progression 694 days after completion of radiation therapy course 1. This case demonstrates that retreatment with radiation therapy to high lifetime doses for recurrent local disease may be well tolerated with IMRT.
