ABSTRACT
Dermatoglyphic pattern analysis, one of the genetic methods, was used to determine digitopalmar ridge count in 40 men with ankylosing spondylitis. Twenty-two variables (ridge count on each of the ten fingers, their sum on five and ten fingers, four traits on each palm, i.e. ridge count between a-b, b-c and c-d triradii, and atd angles on the palms as well as their bilateral sum) were determined. The data thus obtained were compared with digitopalmar prints of 200 healthy men who served as a control group. A significant difference from the control group was found for six variables. The atd angle was reduced on both palms and consequentially in the overall sum. Ridge count was decreased between the b-c triradius on the left palm and increased on the third finger tip bilaterally. Accordingly, a polygenic system identical in some loci to the polygenic system predisposing to ankylosing spondylitis susceptibility might be found responsible for the dermatoglyphic pattern development. That means that they could used, and that is the aim of this study, in the evaluation of the relative risk in family members with positive disease history.
Subject(s)
Dermatoglyphics , Spondylitis, Ankylosing/genetics , Adult , Aged , Aged, 80 and over , Humans , Male , Middle AgedABSTRACT
Palmar and fingerprints of 122 male children with central nervous system lesion were analyzed for possible prevention of cerebral palsy. Eighteen variables of epidermal ridge count were examined: ten on either hand fingers, and four on either palm, and on a-b, b-c and c-d triradii, with atd angle. Patients were divided into two groups: 61 patients with severe lesion (score range 20-29) and 61 patients with moderate lesion (score range 30-39). Fingerprints of 200 male subjects from the Zagreb area served as controls. Statistically significant differences were found for five variables in the group of patients with severe lesion, i.e. on the second finger of the right hand, between a-b and b-c triradii of the right palm, and between a-b and c-d triradii of the left palm. Accordingly, a clinically severe lesion to the central nervous system was quite probably accompanied by certain deviation in the metric traits of the patients' digitopalmar dermatoglyphics, which might prove useful in the diagnosis and prognosis of the disease, thus also for timely and more successful treatment. In children with the presence of risk factors, palmar and fingerprints should be taken in the immediate postnatal period in order to prevent the development of risk symptoms. In those with risk findings, the treatment with intensive medical exercise should be introduced to minimize clinical manifestation of the central nervous system lesion. It should be emphasized that, due to brain plasticity, the best results are obtained if the treatment is performed within nine months after birth, whereafter considerably poorer results are achieved.
Subject(s)
Cerebral Palsy/pathology , Dermatoglyphics , Child , Humans , MaleABSTRACT
Quantitative analysis of digitopalmar ridge count was performed in 40 female patients with rheumatoid arthritis to assess the role of genetic factors. Twenty-two variables (ridge count on each of ten fingers, their sum on five and ten fingers, four traits on each palm, i.e. ridge count between a-b, b-c and c-d triradii, atd angles on two palms and their bilateral sum) were determined. The data obtained were compared with digitopalmar prints of 200 control group women. Statistically significant differences from the control group in terms of increased ridge count were found in nine variables, i.e. on the third, fourth and fifth finger bilaterally, and consequentially in the total ridge count on the fingers of the two hands and of both hands taken together. Dermatologyphics as one of the genetic methods could be used in the evaluation of the relative risk in family members with positive disease history.