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1.
Int Med Case Rep J ; 13: 27-32, 2020.
Article in English | MEDLINE | ID: mdl-32104103

ABSTRACT

To report a treatment of radiation retinopathy in a patient exposed to ionizing radiation for a period of 2 years. A 26-year-old female patient with no comorbidities diagnosed with myelodysplasia confirmed by bone marrow biopsy. She presented a complaint of bilateral progressive visual acuity reduction. At the ophthalmologic examination, she presented alterations suggestive of radiation retinopathy as well as macular thickness to optical coherence tomography (OCT) of over 500 µm. The patient underwent intravitreal injection (0.05 mL) of ranibizumab (Lucentis®) monthly in both eyes and follow-up through visual acuity and OCT examination. She presented reduction of macular edema as well as a slight improvement of visual acuity. In this case, the treatment of radiation retinopathy with intravitreal injection of ranibizumab (Lucentis) was relatively useful, with a slight improvement of visual acuity, due to the regression of macular edema, not being curative.

2.
Ocul Immunol Inflamm ; 24(1): 118-9, 2016.
Article in English | MEDLINE | ID: mdl-24749654

ABSTRACT

PURPOSE: The authors report a case of endophthalmitis after intravitreal injection of ranibizumab. METHODS: After searching for extensive laboratory tests to isolate the etiologic agent Results: The agent was determined as Leuconostoc mesenteroides, gram-positive cocci, vancomycin resistant. DISCUSSION: Considerations regarding this bacterium were done by calling attention to its rarity, difficulty of isolation, and action on secondary comorbidities as opportunistic pathogen.


Subject(s)
Angiogenesis Inhibitors/administration & dosage , Endophthalmitis/microbiology , Eye Infections, Bacterial/microbiology , Gram-Positive Bacterial Infections/microbiology , Leuconostoc/isolation & purification , Postoperative Complications , Ranibizumab/administration & dosage , Aged, 80 and over , Amikacin/therapeutic use , Anti-Bacterial Agents/therapeutic use , Endophthalmitis/diagnosis , Endophthalmitis/drug therapy , Eye Infections, Bacterial/diagnosis , Eye Infections, Bacterial/drug therapy , Gram-Positive Bacterial Infections/diagnosis , Gram-Positive Bacterial Infections/drug therapy , Humans , Intravitreal Injections , Male , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Vitreous Body/microbiology , Wet Macular Degeneration/drug therapy
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