ABSTRACT
Human adult Parvovirus B19 infection is a well known disease most frequently seen in haematology and cancerology. To our knowledge, however, renal involvement in this context has never been reported. A case of severe infection caused by this virus is reported, where multiple organ involvement is associated with acute renal failure. The outcome was favourable with temporary dialysis and symptomatic treatment. Mechanisms of renal failure, presumably multifactorial, are discussed in the light of this case.
Subject(s)
Acute Kidney Injury/microbiology , Erythema Infectiosum , Parvovirus B19, Human , Acute Kidney Injury/pathology , Acute Kidney Injury/physiopathology , Adult , Antibodies, Viral/blood , Humans , Male , Parvovirus B19, Human/immunologyABSTRACT
The conduction velocity of the ulnar, median and peroneal nerves was studied in 21 patients with a severe form of spinal muscular atrophy. They were slower than normal in 16 cases, particularly when the median nerve was studied. The diagnosis criteria of spinal muscular atrophy are discussed according to these data.
Subject(s)
Electromyography , Motor Neurons/physiology , Muscular Atrophy/diagnosis , Neural Conduction , Female , Humans , Infant , Infant, Newborn , Male , Muscular Atrophy/physiopathology , Peripheral Nerves/physiopathologyABSTRACT
Twenty-four patients with recent and acute spinal cord lesions were examined. The somatosensory cerebral evoked potential (SEP) following stimulation of the peroneus communis nerve tested spinal conduction, whereas the H reflex showed spinal excitability belowe the lesion. After complete spinal cord section, the SEP was always abolished and the H reflex was absent in most cases tested in the first 24 hours. Into other patients, the recruitment curve and the recovery cycle of the H reflex displayed some abnormalities which progressively disappeared. With partial lesions, SEP could occasionally be altered. Some abnormalities of the H reflex recovery cycle, of the same type as those seen in the late stage of complete sections, were also observed. These data give nre information on the physiopathology of spinal shock; they lead to the distinction of several evolutionary stages after acute spinal lesions and also have prognostic disgnificance.
Subject(s)
Electroencephalography , H-Reflex , Reflex, Monosynaptic , Spinal Cord Injuries/diagnosis , Adolescent , Adult , Aged , Cerebral Cortex/physiopathology , Child , Child, Preschool , Electric Stimulation , Evoked Potentials , Humans , Infant , Middle Aged , Neural Conduction , Peroneal Nerve/physiopathology , Prognosis , Spinal Cord Injuries/physiopathologyABSTRACT
The motor conduction velocity (MCV) and various parameters of the Hoffman reflex were studied in 55 diabetics compared to a control population of the same age. In the diabetics there were statistically significant alterations of the MCV, the Hmax/Mmax ratio and the H index, which are closely connected. These changes were more precise when there were clinical signs of neuropathy (absence of the Achilles reflex) but they still existed in the absence of signs. The older the diabetics, the more the electro-physiological parameters were altered. However, the H index is abnormal earlier than the Hmax-Mmax ratio or the MCV. Changes in the excitability cycle to double shock involve mainly phase IV of secondary facilitation and may be related to central disturbances.
