Subject(s)
Biliary Tract Surgical Procedures/adverse effects , Corneal Diseases/diagnosis , Corneal Diseases/etiology , Postoperative Complications/diagnosis , Prosthesis Implantation/adverse effects , Atrophy/diagnosis , Biliary Tract Surgical Procedures/methods , Chronic Disease , Cornea/diagnostic imaging , Cornea/pathology , Corneal Diseases/pathology , Fundus Oculi , Glucose Intolerance/etiology , Glucose Intolerance/surgery , Humans , Jaundice/complications , Jaundice/surgery , Male , Middle Aged , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/surgery , Syndrome , Tomography, Optical CoherenceSubject(s)
Pseudoxanthoma Elasticum/diagnosis , Diagnosis, Differential , Female , Humans , Middle Aged , Neck , Skin AgingABSTRACT
INTRODUCTION: We report a case of a patient with orbital pseudotumors associated with Riedel's thyroiditis. This association of unknown etiology may be related to idiopathic multifocal fibrosclerosis that includes retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Riedel's thyroiditis, and orbital pseudotumors. CASE REPORT: A 44-year-old woman was referred for a bilateral inflammatory malignant exophthalmos with progressive optical neuropathy (bilateral visual acuity<1/20). Imaging studies demonstrated bilateral exophthalmos (grade III) with compression of the both optic nerves by extensive tumoral infiltration. The general work-up showed a compressive goiter, with the histopathologic examination establishing the diagnosis of Riedel's thyroiditis. Orbital biopsy and antithyroid antibody testing were not contributive. Systemic corticosteroid associated with total thyroidectomy resulted in regression of the symptoms within 3 months. DISCUSSION: The coexistence of bilateral orbital pseudotumor and Riedel's thyroiditis is the most common situation found for idiopathic multifocal fibrosclerosis. We discuss the differential diagnosis with thyroid-associated orbitopathy and orbital lymphoma. This observation is original because the diagnosis was reached by ophthalmic manifestation. The ophthalmologist should be able to identify this pathology to optimize the diagnostic and the therapeutic strategy. CONCLUSION: In case of exophthalmos, a complete assessment should be made, including radiological and histopathological orbital and thyroid work-up.
Subject(s)
Exophthalmos/etiology , Goiter/complications , Orbital Pseudotumor/etiology , Thyroiditis/complications , Adrenal Cortex Hormones/therapeutic use , Adult , Carcinoma, Papillary/complications , Carcinoma, Papillary/surgery , Chronic Disease , Diagnosis, Differential , Female , Fibrosis , Goiter/surgery , Humans , Incidental Findings , Lymphoma/diagnosis , Magnetic Resonance Imaging , Nerve Compression Syndromes/etiology , Optic Nerve Diseases/etiology , Orbital Neoplasms/diagnosis , Orbital Pseudotumor/diagnosis , Orbital Pseudotumor/drug therapy , Thyroid Gland/pathology , Thyroid Neoplasms/complications , Thyroid Neoplasms/surgery , Thyroidectomy , Thyroiditis/diagnosis , Thyroiditis/drug therapy , Thyroiditis/pathologyABSTRACT
Choroidal folds are rare but systematic research on the fluorography allows to affirm or confirm their diagnosis.
Subject(s)
Choroid Diseases/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Choroid Diseases/diagnosis , Choroid Diseases/epidemiology , Choroid Diseases/etiology , Female , Fluorescein Angiography , Humans , Male , Middle AgedABSTRACT
Descending ocular myopathy is a rare progressive disease characterized by bilateral ptosis, external ophthalmoplegia and progressive dystrophy of the proximal skeletal muscles. A case of descending ocular myopathy with post-operative corneal ulceration is reported. Mitochondrial abnormalities are found on skeletal muscle biopsy. Nosologic classification of this case is discussed.
