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Front Endocrinol (Lausanne) ; 12: 727628, 2021.
Article in English | MEDLINE | ID: mdl-34557164

ABSTRACT

Endocrine tests are the cornerstone of diagnosing multiple diseases that primary care physicians are frequently faced with. Some of these tests can be affected by situations that affect the proper interpretation, leading to incorrect diagnoses and unnecessary treatment, such as the interference of biotin with thyroid function test, falsely elevated prolactin values in presence of macroprolactinemia or falsely normal due to the "hook effect" in macroprolactinomas. Recognizing these situations is essential for the clinician to make an adequate interpretation of these tests as well as an accurate diagnosis that guarantees the best outcomes for the patient.


Subject(s)
Data Interpretation, Statistical , Diagnostic Techniques, Endocrine , Artifacts , Blood Chemical Analysis/standards , Blood Chemical Analysis/statistics & numerical data , Diagnostic Techniques, Endocrine/standards , Diagnostic Techniques, Endocrine/statistics & numerical data , False Negative Reactions , False Positive Reactions , Humans , Prolactin/blood , Prolactin/physiology , Prolactinoma/blood , Reference Standards , Thyroid Function Tests/standards , Thyroid Function Tests/statistics & numerical data
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