Hemosiderotic dermatofibroma: report of one case.

Dermatofibroma (DF) is a common benign fibrohistiocytic lesion which presents with a wide variety of clinicopathological features. Generally, the clinical diagnosis is easy, but differentiating it from other cutaneous tumors could be difficult in atypical cases and rare variants. We may find at least four different histopathological variants of DF; more than one of which may be present in a single tumor. Hemosiderotic DF is a variant composed of numerous small vessels, extravasated erythrocytes, and intra- and extracellular hemosiderotic deposits. The differential diagnosis may comprise melanoma as well as other melanocytic and nonmelanocytic tumors. We report the case of a 38-year-old man who presented with a hemosiderotic DF on the abdomen.

[Drugs used in the therapy of peptic ulcer with special reference to H2 receptor blockaders]. / Farmaci impiegati nella terapia dell'ulcera peptica con particolare riferimento agli anti-H2.

Drugs used in the management of peptic ulcer are reviewed with special attention to the possibilities offered by H2 receptor antagonists. In this context, histaminergic transmission and distribution of H2 receptors are briefly reviewed. Among other substances, special interest has been raised by H+ and K+-dependent ATPase inhibitors; the most recently introduced derivatives of these substances which are as yet in the experimental stage, are also listed.