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1.
J Oral Rehabil ; 2024 Apr 29.
Article in English | MEDLINE | ID: mdl-38685704

ABSTRACT

OBJECTIVE: This prospective study is part of a randomised clinical trial and reports the changes in masticatory performance (MP) and bite force, and explores their influential factors, 1 year after the provision of mandibular overdentures retained by four titanium-zirconium mini implants. METHODS: Edentulous patients received conventional complete dentures, followed by placement of four mini implants (Straumann® Mini Implant System) in the anterior mandible and converting the conventional prosthesis into a mandibular overdenture. Treatment protocols were randomised using a 2×2 factorial design combining different surgical (flapped vs. flapless) and loading (immediate vs. delayed) protocols. MP was assessed using a two-colour mixing ability test and a colorimetric analysis to measure the level of colour mixing (Variance of Hue-VoH). Maximum voluntary bite force (MBF) was measured by a digital gnathodynamometer in the posterior and anterior regions. Sex, age, surgical and loading protocols and ridge morphology were tested as independent variables. MP and MBF tests were performed at baseline (pre-treatment) and the 3-, 6- and 12-month after implant loading. Descriptive statistics, independent t-test, and linear mixed-effect model (LMM) regression were used for data analysis. RESULTS: Seventy-four participants were assessed and 73 completed the 1-year follow-up. Statistically significant improvements in functional parameters were observed in all follow-up periods compared to baseline (p < .001). The flapless protocol was associated with higher improvement in MP at the 3-month follow-up (p = .004), while less resorbed ridges were associated with better MP (p = .038) and higher MBF (p < .001). CONCLUSION: The mandibular overdenture protocol using four titanium-zirconium mini implants was effective in improving MP and MBF of edentulous patients, compared to pre-treatment values. The findings also suggest that improvements in chewing function and bite force are impacted by clinical factors since better outcomes were observed for flapless surgeries and less resorbed edentulous ridges. CLINICAL TRIAL REGISTRATION: ClinicalTrials.Gov ID NCT04760457.

2.
J Esthet Restor Dent ; 36(3): 477-483, 2024 Mar.
Article in English | MEDLINE | ID: mdl-37877244

ABSTRACT

OBJECTIVE: The purpose of this in vitro study was to evaluate the effect of potassium aluminum sulfate (alum) application on the stainability and translucency of computer-aided design and computer-aided manufacturing (CAD-CAM) materials after coffee thermocycling (CTC). MATERIALS AND METHODS: Disk-shaped specimens (Ø10 × 1 mm; N = 200) were fabricated by using additively (Crowntec [CT] and Varseo Smile Crown Plus [VS]) and subtractively manufactured (Brilliant Crios [RCR], CEREC Block [FC], and Vita Enamic [VE]) CAD-CAM materials and polished. All specimens were randomly divided into two groups as alum applied and control (n = 10). All specimens were then subjected to CTC (10,000 cycles at 5-55°C) and color coordinates were measured at each time interval. Color differences (ΔE00 ) and relative translucency parameters (RTPs) were calculated and the data were statistically analyzed (a = 0.05). RESULTS: Among tested time intervals, alum applied specimens had their lowest ΔE00 after alum application (p ≤ 0.006), except for FC (p = 0.177). In addition, alum applied RCR had lower ΔE00 values than its control specimens (p = 0.029). Alum applied specimens had their lowest RTP after CTC (p < 0.001) and alum application decreased the RTP of CT (p = 0.010). CTC reduced the RTP of all materials in control groups (p < 0.001). Alum applied CT had higher RTP than its control specimens (p = 0.049). CONCLUSIONS: Alum application's effect on color change varied depending on the material and alum mostly resulted in clinically acceptable changes in translucency. CTC led to unacceptable color and translucency changes based on previously reported threshold values. CLINICAL SIGNIFICANCE: Optical properties of CAD-CAM materials and the sustainability of these properties over time is critical for longevity. Alum may improve the color stability of reinforced composite resin when subjected to long-term coffee consumption.


Subject(s)
Alum Compounds , Coffee , Dental Porcelain , Color , Materials Testing , Surface Properties , Ceramics , Computer-Aided Design
3.
J Prosthodont ; 2023 Nov 10.
Article in English | MEDLINE | ID: mdl-37947220

ABSTRACT

PURPOSE: To evaluate the surface roughness, optical properties, and microhardness of additively or subtractively manufactured CAD-CAM materials after simulated brushing and coffee thermal cycling. MATERIAL AND METHODS: Two additively manufactured resins (Crowntec, CT and VarseoSmile Crown Plus, VS) and 3 subtractively manufactured materials (a reinforced composite (Brilliant Crios, BC), a polymer-infiltrated ceramic network (Enamic, VE), and a feldspathic ceramic (Mark II, VM)) were used to fabricate disk-shaped specimens (Ø10×1-mm) (n = 10). Surface roughness, Vickers microhardness, and color coordinates were measured after polishing, while surface roughness was also measured before polishing. Specimens were then subjected to 25000 cycles of brushing and 10000 cycles of coffee thermal cycling, and measurements were repeated after each time interval. Color difference (ΔE00 ) and relative translucency parameter (RTP) were calculated. Robust analysis of variance test was used to evaluate surface roughness, ΔE00 , and RTP data, while generalized linear model analysis was used for microhardness data (α = 0.05). RESULTS: Material type and time interval interaction affected tested parameters (p ≤ 0.002). In addition, material type affected all parameters (p < 0.001) other than surface roughness (p = 0.051), and time interval affected surface roughness and microhardness values (p < 0.001). Tested materials mostly had their highest surface roughness before polishing (p ≤ 0.026); however, there was no clear trend regarding the roughness of materials within different time intervals along with ΔE00 and RTP values within materials or time intervals. VS and CT had the lowest microhardness regardless of the time interval, while the remaining materials were listed as VM, VE, and BC in decreasing order (p < 0.001). Coffee thermal cycling only reduced the microhardness of VM (p < 0.001). CONCLUSIONS: Tested additively manufactured resins can be considered more susceptible to simulated brushing and coffee thermal cycling than the other materials, given the fact that their surface roughness and ΔE00 values were higher than previously reported acceptability thresholds and because they had the lowest microhardness after all procedures were complete.

4.
J Clin Med ; 12(11)2023 May 30.
Article in English | MEDLINE | ID: mdl-37297955

ABSTRACT

According to the World Health Organization (WHO), the estimated number of older adults is around 962 million and is projected to increase to 2.1 billion by 2050. The oral frailty concept is associated with gradual oral function loss in relation to aging. There is a need to emphasize the improvement of oral function based on an evaluation of masticatory performance in patients with various oral conditions or systemic diseases and especially in the frail elderly. The present narrative review presents an overview of the current state of the assessment and improvement of masticatory performance in frail older people. To fully encompass oral frailty, oro-facial hypofunction, or oro-facial fitness, dental Patient Reported Outcomes (dPROs) should be included; nevertheless, there are limited evidence-based rehabilitation approaches. The concept of oral frailty, oro-facial hypofunction, or oro-facial fitness should involve dental Patient Reported Outcomes (dPROs), and in this sense, there are only a few evidence-based rehabilitation procedures to improve oro-facial hypofunction besides prosthodontics. It must be considered that reduced neuroplastic capacity in old individuals might preclude a positive outcome of these strategies that might need to be accompanied by functional training and nutritional counseling.

5.
J Dent ; 134: 104548, 2023 07.
Article in English | MEDLINE | ID: mdl-37192693

ABSTRACT

OBJECTIVES: To evaluate the effect of number of supports and build angle on the fabrication and internal fit accuracy (trueness and precision) of additively manufactured resin-ceramic hybrid crowns. METHODS: A mandibular first molar crown was designed and nested on the build platform of a printer either with a 30° angle between the occlusal surface and the build platform (BLS (less support) and BMS (more support)) or its occlusal surface parallel to the build platform (VLS (less support) and VMS (more support)) to fabricate additively manufactured resin-ceramic hybrid crowns (n = 14). After fabrication, supports were removed by a blinded operator and all crowns were digitized with an intraoral scanner. Fabrication accuracy (overall, external, intaglio occlusal, occlusal, and marginal) was evaluated by using root mean square (RMS) method, while internal fit was evaluated with triple scan method. RMS, average gap, and precision of these data were analyzed (α= 0.05). RESULTS: VLS had higher overall deviations than BLS and VMS (P≤.039). VMS had higher occlusal deviations than BLS (P=.033). While BMS and BLS had higher marginal deviations than VLS (P≤.006), BMS also had higher values than VMS (P=.012). BLS led to higher precision than VMS (intaglio occlusal and occlusal surfaces) and VLS (occlusal surface) (P≤.008). VLS led to higher precision than BMS (marginal surface) (P=.027). Average gap values were similar (P=.723); however, BLS resulted in higher precision than VLS (P=.018). CONCLUSIONS: Considering their high marginal and occlusal surface trueness, and similar internal occlusal deviations and average gaps (trueness), clinical fit of resin-ceramic hybrid crowns fabricated with tested parameters may be similar. Reduced number of supports and angled orientation may lead to higher precision of fit. CLINICAL SIGNIFICANCE: Tested resin-ceramic hybrid-printer pair may be used to fabricate crowns with reduced number of supports to maintain occlusal surface integrity without compromising the fabrication accuracy and fit.


Subject(s)
Dental Porcelain , Dental Prosthesis Design , Dental Impression Technique , Computer-Aided Design , Dental Marginal Adaptation , Crowns , Ceramics
6.
J Oral Rehabil ; 50(5): 392-399, 2023 May.
Article in English | MEDLINE | ID: mdl-36789570

ABSTRACT

BACKGROUND: Several complete denture wearers have major complaints and may be benefitted from implant treatment. However, the factors that shape the demand for and utilization of implants need further investigation. OBJECTIVE: The aim was to evaluate edentulous patient's willingness to accept or refuse the offer and provision of implant-retained treatment. METHODS: As part of a clinical trial, edentulous subjects were offered a mandibular overdenture retained by four mini-implants opposing a conventional maxillary denture. Treatment was offered without any financial costs for the patients. Patients' level of interest in receiving treatment was assessed using a 5-point Likert scale, and they were asked to respond to a list of reasons that led to their decision to accept or refuse implants. Those who refused implants received conventional prosthodontic interventions as required, and those who accepted implant treatment underwent surgical planning and implant placement. RESULTS: Of 175 eligible subjects, 147 accepted the offer of treatment and were invited to take part in the study (69.4% women, mean age 67.4 ± 10.0 years). Overall, 111 patients (75.5%) expressed a positive intention to undergo implant treatment at the initial contact. Implant treatment was performed for 56.3% (9/16) of those who answered 'probably yes' about their level of interest in implant treatment on the Likert scale, and 69.6% (64/92) of 'certainly yes' (p < .001). Older subjects were less likely to receive implants (OR = 0.93; p = .036), whilst those with a positive intention towards implants (OR = 3.15; p = .001), those previously treated by the dental team (OR = 7.89; p < .001), and who actively demanded implants (OR = 18.1; p < .001) were more likely to accept treatment. Improved chewing was the most common reason for accepting implants, whilst fear of surgery was the most reported reason for refusal. CONCLUSION: Refusal of implants was high among edentate patients even when financial costs were removed. Patients' initial attitude towards acceptance is a key factor in the demand for and uptake of implant therapy.


Subject(s)
Dental Implants , Jaw, Edentulous , Mouth, Edentulous , Humans , Female , Middle Aged , Aged , Male , Prospective Studies , Patient Satisfaction , Denture, Overlay , Jaw, Edentulous/surgery , Mandible/surgery , Dental Prosthesis, Implant-Supported , Denture Retention
7.
Clin Implant Dent Relat Res ; 25(2): 426-434, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36623506

ABSTRACT

OBJECTIVE: The aim of this study was to assess the final insertion torque values achieved using site-specific drilling protocols for a novel mini implant system for removable complete overdentures. Anatomical and technical factors influencing final insertion torque were recorded and analyzed. MATERIAL AND METHODS: Participants were randomized to two surgical protocol groups (flapped or flapless) and all received four mini implants (Straumann® mini implant system; Straumann AG) in the anterior mandible, using a 1.6 mm needle drill and a 2.2 mm pilot drill for the implant bed site preparation. The final insertion torque was recorded as the main outcome variable during surgery. Bone type, radiographical bone density, ridge form, implant length, and the drilling protocol were considered as independent variables. Descriptive statistics, generalized estimating equations (GEE) regression, and heatmap charts were used for data analyses. RESULTS: A total of 296 mini implants were placed in 74 patients (mean age = 64.1 ± 8.0; 64.9% female) using flapless (n = 37) or flapped (n = 37) surgeries. Mean final insertion torque was 55.8 ± 18.4 Ncm (10.5% > 35 Ncm, 48.9% between 35 and 65 Ncm, and 40.6% > 65 Ncm). The needle drill was used in only 43.9% of the implant bed sites. Higher final torque values were observed for higher bone densities (bone type I > II > III, and D1-D2 > D3-D4), highly resorbed ridge forms (5-6 > 3-4), flapped surgeries, and male patients. However, regression models showed that the likelihood of achieving optimal insertion torque (≥35 and ≤65 Ncm) was higher for females (OR = 2.14; 95%CI = 1.14-4.01; p = 0.018), ridge forms 3-4 (OR = 2.87; 95%CI = 1.05-7.85; p = 0.040), and flapless surgeries (OR = 1.96; 95%CI = 1.09-3.51; p = 0.024). CONCLUSIONS: Sufficient primary stability for immediate loading was achieved for the majority of the mini implants placed. Surgical implant bed preparation should be site-specific to achieve optimal primary stability for immediate loading while avoiding excessive insertion torque.


Subject(s)
Dental Implantation, Endosseous , Dental Implants , Humans , Male , Female , Middle Aged , Aged , Dental Implantation, Endosseous/methods , Titanium , Cross-Sectional Studies , Zirconium , Torque , Denture, Overlay , Mandible/surgery , Randomized Controlled Trials as Topic
8.
J Dent ; 130: 104388, 2023 03.
Article in English | MEDLINE | ID: mdl-36502966

ABSTRACT

OBJECTIVES: To evaluate the effect of different measurement techniques and operators on measured deviations in vitro implant scans. METHODS: A 2-piece system that comprises a healing abutment (HA) and a scan body (SB) was mounted onto an implant at right first molar site of a polymethylmethacrylate mandibular dentate model. Model was digitized by using an industrial scanner (reference model scan, n = 1) and an intraoral scanner (test scan, n = 20). All standard tessellation language files were imported into a 3-dimensional analysis software and superimposed. Three operators with similar experience performed circle-based and point-based deviation analyses (n = 20). Deviations measured with different techniques were compared with paired samples t-test within each operator, while the reliability of the operators was assessed by using F-tests for both technqiues (α = 0.05). RESULTS: Point-based technique resulted in lower deviations than circle-based technique for all operators (P = .001) with to higher reliability among operators (ICC = 0.438, P = .001). The correlation among the operators was nonsignificant when circle-based technique was used (ICC = 0.114, P = .189). CONCLUSION: Lower deviations were detected with the point-based technique. In addition, different operators' measurements had higher correlation when point-based technique was used compared with circle-based technique. CLINICAL SIGNIFICANCE: Point-based technique may be preferred over circle-based technique for research studies on scan accuracy of implants, given its higher reliability. The accuracy of measured deviations may increase if the number of planes are increased, which can facilitate point generation at different surfaces of the scan body.


Subject(s)
Computer-Aided Design , Dental Implants , Reproducibility of Results , Dental Impression Technique , Models, Dental , Imaging, Three-Dimensional
9.
J Prosthet Dent ; 128(6): 1318.e1-1318.e9, 2022 Dec.
Article in English | MEDLINE | ID: mdl-36435670

ABSTRACT

STATEMENT OF PROBLEM: Additive manufacturing is commonly used for the fabrication of definitive casts with removable dies. However, how the trueness and fit of removable dies are affected by printing layer thickness is lacking. PURPOSE: The purpose of this in vitro study was to investigate the trueness and fit of additively manufactured removable dies printed in different layer thicknesses. MATERIAL AND METHODS: A mandibular cast with a prepared right first molar tooth was digitized (CEREC Primescan), and its standard tessellation language (STL) file was imported into a software program (DentalCAD 3.0). A removable die (D-STL) and a hollow cast with (M-STL) or without the die (SM-STL) were designed. D-STL and SM-STL were imported into a nesting software program (Composer), and 45 removable dies in 3 layer thicknesses (100 µm, 50 µm, and 50 to 100 µm) (n=15) and 1 cast (100-µm) were additively manufactured. Each removable die (TD-STLs), the cast with each die (TM-STLs), and the cast without the die (TSM-STL) were digitized by using the same scanner. All STL files were imported into a software program (Medit Link v 2.4.4), and TD-STLs were superimposed over D-STL. The root mean square (RMS) method was used to analyze the trueness of the dies at 2 different areas (crown and root portion) and as a complete unit (overall). Overall RMS values of the cast with and without the die were also calculated after superimposing TM-STLs over M-STL. The fit of the dies in the cast was evaluated by using a triple-scan protocol to measure deviations at 5 different points (point M: most mesial point of the margin; point TM: tip of the mesial cusp; point O: deepest point of the occlusal fossa; point TD: tip of the distal cusp; point D: most distal point of the margin) on the crown portion. One-way ANOVA and Tukey honestly significant difference tests were used to evaluate data (α=.05). RESULTS: The RMS values of removable dies showed significant differences at each area (P≤.002). The 50- to 100-µm group had higher overall RMS values than the 100-µm group (P=.017). The 100-µm group had the highest RMS values for the crown portion (P≤.019), while the 50-µm group had the highest RMS values for the root portion (P<.001). The 50-µm group had the lowest RMS values for the crown portion when the die was in the cast (P<.001). Except for point TM (P=.228), significant differences were observed among the test groups at all points (P<.001). The 50-µm group had the lowest distance deviations at points M, TD, and D (P≤.005), while the 100-µm group had the highest distance deviations at points O and D (P≤.010). CONCLUSIONS: Removable dies fabricated by using a 100-µm or 50- to 100-µm combined layer thickness had trueness that was either similar to or better than that of dies fabricated with a 50-µm layer thickness. When the die was on the cast, the 50-µm layer thickness resulted in the best crown portion trueness. However, because the deviation differences among groups were clinically small, the 100-µm layer thickness can be considered for the efficient fabrication of removable dies when the tested printer and resin are used.


Subject(s)
Computer-Aided Design , Crowns , Software , Printing, Three-Dimensional
10.
Materials (Basel) ; 15(18)2022 Sep 16.
Article in English | MEDLINE | ID: mdl-36143757

ABSTRACT

Three-dimensional (3D) printing is increasingly used to fabricate denture base materials. However, information on the effect of simulated brushing and thermocycling on the surface roughness and color stability of 3D-printed denture base materials is lacking. The aim of this study was to evaluate the effect of brushing and thermocycling on the surface roughness and color stability of 3D-printed denture base materials and to compare with those of milled and heat-polymerized denture base resins. Disk-shaped specimens (Ø 10 mm × 2 mm) were prepared from 4 different denture base resins (NextDent Denture 3D+ (ND); Denturetec (SC); Polident d.o.o (PD); Promolux (CNV)) (n = 10). Surface roughness (Ra) values were measured before and after polishing with a profilometer. Initial color coordinates were measured by using a spectrophotometer after polishing. Specimens were then consecutively subjected to simulated brushing (10,000 cycles), thermocycling (10,000 cycles), and brushing (10,000 cycles) again. Ra and color coordinates were measured after each interval. Color differences (ΔE00) between each interval were calculated and these values were further evaluated considering previously reported perceptibility (1.72 units) and acceptability (4.08 units) thresholds. Data were analyzed with Friedman, Kruskal-Wallis, and Mann-Whitney U tests (α = 0.05). Ra (p ≥ 0.051) and ΔE00 (p ≥ 0.061) values among different time intervals within each material were similar. Within each time interval, significant differences in Ra (p ≤ 0.002) and ΔE00 values (p ≤ 0.001) were observed among materials. Polishing, brushing, and thermocycling resulted in acceptable surface roughness for all materials that were either similar to or below 0.2 µm. Color of ND printed resin was affected by brushing and thermocycling. All materials had acceptable color stability when reported thresholds are considered.

11.
J Prosthet Dent ; 2022 Aug 19.
Article in English | MEDLINE | ID: mdl-35995602

ABSTRACT

STATEMENT OF PROBLEM: Denture bases machined from prepolymerized materials have become popular. However, information on the effect of simulated brushing and coffee thermocycling (CTC) on their surface roughness and stainability is lacking. PURPOSE: The purpose of this in vitro study was to compare the effect of simulated brushing and CTC on the surface roughness (Ra) and stainability of computer-aided design and computer-aided manufacturing (CAD-CAM) denture base materials and a heat-polymerized denture base material. MATERIAL AND METHODS: Forty disk-shaped specimens were prepared from 3 CAD-CAM denture base resins (AvaDent, AV; Merz M-PM, M-PM; and Polident d.o.o, Poli) and a heat-polymerized polymethylmethacrylate resin (Promolux, CV) (n=10). Ra values of the specimens were measured by using a noncontact profilometer after conventional polishing. The color coordinates were also measured over a gray background with a spectrophotometer. Specimens were then consecutively subjected to simulated brushing for 20 000 cycles, CTC for 5000 cycles, and another 10 000 brushing cycles. Ra and color coordinates were measured after each interval. Color differences (ΔE00) were calculated by using the CIEDE2000 formula, and the data were analyzed by using 2-way analysis of variance and Tukey honestly significant difference tests (α=0.05). RESULTS: The time interval had a significant effect on Ra (P<.001) as brushing cycles resulted in higher values than those at baseline and after CTC (P<.001). However, the differences between brushing cycles (P=.143) and between the baseline and after CTC (P=.994) were not significant. The interaction between the material type and time interval was significant for ΔE00 (P=.016). The only significant difference in ΔE00 values was observed between M-PM and CV after all treatments were completed (P=.029). CONCLUSIONS: Brushing increased the Ra of all materials when compared with the baseline. All materials showed similar stainability throughout the brushing and CTC processes. However, M-PM CAD-CAM denture base resin underwent a greater color change after all treatments were completed than conventional denture base resin. All color changes can be considered clinically small, considering reported perceptibility and acceptability thresholds.

12.
Clin Oral Implants Res ; 33(9): 953-964, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35818640

ABSTRACT

OBJECTIVE: This factorial randomized clinical trial (RCT) tested the effects of the surgical approach (flapped-FPS vs. flapless-FLS surgery) and loading protocol (delayed-DL vs. immediate-IL) for treatment with a four mini implant mandibular overdenture. MATERIAL AND METHODS: A total of 296 one-piece titanium-zirconium mini-implants were inserted in 74 patients (IL/FLS = 17; IL/FPS = 18; DL/FLS = 20; and DL/FPS = 19). Outcomes included patient's perceived surgical burdens, clinical time, implant survival, and post-surgical symptoms and complications, assessed immediately after surgery, in the 7-day and 6-week follow-ups. RESULTS: Perceived surgical burdens were relatively low, higher for females, and no difference was found between FPS and FLS surgery. Surgical time was lower for FLS surgery. Overall symptoms were mild after 24 h, and higher for females. Less symptoms were recorded for the FLS surgery compared to the FPS for the delayed loading patients, and FLS surgery was associated with a lower risk of bleeding. No early implant failure was observed until the 6-week follow-up. Delayed was associated with discontinuous use of the prosthesis and poor function. Lower complaint rates were observed for immediate loading regardless of the surgery protocol. CONCLUSIONS: Mini implants for mandibular overdenture are a feasible option regardless of surgical access and loading protocol, with high safety and predictable survival rates, and low incidence of post-insertion complications. FLS surgery requires less clinical time and results in easier intraoral prosthetic incorporation of attachments compared to FPS surgeries. Immediate loading did not increase the risk of early implant failure when satisfactory primary stability was achieved.


Subject(s)
Dental Implants , Immediate Dental Implant Loading , Dental Implantation, Endosseous/methods , Dental Prosthesis, Implant-Supported , Dental Restoration Failure , Denture, Overlay , Female , Follow-Up Studies , Humans , Immediate Dental Implant Loading/methods , Mandible/surgery , Treatment Outcome
13.
J Dent ; 103: 103521, 2020 12.
Article in English | MEDLINE | ID: mdl-33159977

ABSTRACT

OBJECTIVE: Denture fracture is one of the most common complications in prosthodontics and implant overdentures are reported to be at higher risk of fractures. Therefore, the aim of this study was to assess the incidence and factors associated with the occurrence of fractures in patients treated with a single implant mandibular overdenture (SIMO) opposed by a conventional maxillary complete denture. METHODS: A cohort of 152 patients, 65.1% female and 34.9% male, mean age 65.4 ± 8.5 years, were prospectively followed-up for a minimum of 1 year and up to 6.7 years. Patients received a single midline mandibular implant with a retention system incorporated in the overdenture: Straumann ball abutment and gold elliptical matrix (n = 37), Neodent ball/nylon matrix (n = 83), or Neodent Equator/nylon matrix (n = 32). Fracture was defined as a complete separation of denture parts and classified as midline fracture (over the implant region), or elsewhere. No metal reinforcement was incorporated into the overdenture. Incidence rates, life table analysis, Kaplan-Meier, and Cox regression were used for data analysis. RESULTS: Overdenture fractures occurred in 49 patients (32.2% incidence), with repeated fractures in 16 patients. The majority of fractures were associated with function (42.6%) or due to the overdenture being dropped (36.8%). Overall incidence density was 0.14 fracture/patient/year. The risk of fracture was associated with the duration of the overdenture use (HR = 0.84; 95%CI = 0.71-0.99). CONCLUSION: Midline denture fracture was a common complication in patients receiving SIMO treatment regardless of the implant / retention system. The use of metal reinforcement may be considered to reduce the risk of recurrent fractures. CLINICAL SIGNIFICANCE: This clinical prospective study showed that single-implant mandibular overdentures are at high risk of midline fractures. Proper post-insertion monitoring and the identification and management of patient's individual risk factors are essential for the successful treatment in the long-term.


Subject(s)
Dental Implants , Denture, Overlay , Aged , Dental Implants/adverse effects , Dental Prosthesis, Implant-Supported , Denture Retention , Denture, Complete, Lower , Female , Humans , Incidence , Male , Mandible , Middle Aged , Prospective Studies
14.
J Fungi (Basel) ; 6(4)2020 Oct 12.
Article in English | MEDLINE | ID: mdl-33053811

ABSTRACT

Paracoccidioides is a genus of thermodimorphic fungi that causes paracoccidioidomycosis. When in the host, the fungus undergoes several challenges, including iron deprivation imposed by nutritional immunity. In response to the iron deprivation triggered by the host, the fungus responds in a ternary manner using mechanisms of high affinity and specificity for the uptake of Fe, namely non-classical reductive iron uptake pathway, uptake of host iron proteins, and biosynthesis and uptake of siderophores. This triple response resembles the rhythmic structure of a waltz, which features three beats per compass. Using this connotation, we have constructed this review summarizing relevant findings in this area of study and pointing out new discoveries and perspectives that may contribute to the expansion of this "little iron waltz".

15.
J Prosthodont Res ; 60(1): 47-53, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26589845

ABSTRACT

PURPOSE: To evaluate the effect of glass fiber/filler particles proportion on flexural strength and diametral tensile strength of an experimental fiber-reinforced composite. METHODS: Four experimental groups (N=10) were created using an experimental short fiber-reinforced composite, having as a factor under study the glass fiber (F) and filler particle (P) proportion: F22.5/P55 with 22.5 wt% of fiber and 55 wt% of filler particles; F25/P52.5 with 25 wt% of fiber and 52.5 wt% of filler particles; F27.5/P50 with 27.5 wt% of fiber and 50 wt% of filler particles; F30/P47.5 with 30 wt% of fiber and 47.5 wt% of filler particles. The experimental composite was made up by a methacrylate-based resin (50% Bis-GMA and 50% TEGDMA). Specimens were prepared for Flexural Strength (FS) (25 mm × 2 mm × 2 mm) and for Diametral Tensile Strength (DTS) (3×6 Ø mm) and tested at 0.5 mm/min in a universal testing machine. RESULTS: The results (in MPa) showed significance (different superscript letters mean statistical significant difference) for FS (p<0.009) and DTS (p<0.001)--FS results: F22.5/P55: 217.24±20.64(B); F25/P52.5: 245.77±26.80(AB); F27.5/P50: 246.88±32.28(AB); F30/P47.5: 259.91±26.01(A). DTS results: F22.5/P55: 21.82±4.42(B); F25/P52.5: 22.00±7.40(B); F27.5/P50: 18.63±4.41(B); F30/P47.5: 31.05±2.97(A). In SEM analysis, areas without fiber reinforcement demonstrated to be more prone to the presence of bubbles and crack development. The group F30/P47.5 showed areas with a great quantity of fibers without empty spaces for crack propagation. CONCLUSION: Increasing fiber content results in higher flexural and diametral tensile strength of an experimental composite reinforced with glass fibers.


Subject(s)
Acrylic Resins , Composite Resins , Dental Materials , Dental Stress Analysis , Glass , Polyurethanes , Tensile Strength , Methacrylates , Stress, Mechanical
16.
Biomed Res Int ; 2014: 364398, 2014.
Article in English | MEDLINE | ID: mdl-24967361

ABSTRACT

This study evaluated the influence of silane heat treatment and glass fiber fabrication type, industrially treated (I) or pure (P), on flexural and compressive strength of methacrylate resin bars (BISGMA/TEGDMA, 50/50%). Six groups (n = 10) were created: I-sil: I/silanated; P-sil: P-silanated; I-sil/heat: I/silanated heated to 100°; P-sil/heat: P/silanated heated to 100°; (I: I/not silanated; and P: P/not silanated. Specimens were prepared for flexural strength (10 × 2 × 1 mm) and for compressive strength 9.5 × 5.5 × 3 mm) and tested at 0.5 mm/min. Statistical analysis demonstrated the following for flexural strength (P < 0.05): I-sil: 155.89 ± 45.27(BC); P-sil: 155.89 ± 45.27(BC); I-sil/heat: 130.20 ± 22.11(C); P-sil/heat: 169.86 ± 50.29(AB); I: 131.87 ± 15.86(C). For compressive strength, the following are demonstrated: I-sil: 1367.25 ± 188.77(ab); P-sil: 867.61 ± 102.76(d); I-sil/heat: 1162.98 ± 222.07(c); P-sil/heat: 1499.35 ± 339.06(a); and I: 1245.78 ± 211.16(bc). Due to the impossibility of incorporating the stipulated amount of fiber, P group was excluded. Glass fiber treatment with heated silane enhanced flexural and compressive strength of a reinforced dental methacrylate.


Subject(s)
Bisphenol A-Glycidyl Methacrylate/chemistry , Dental Cements/chemistry , Glass/chemistry , Materials Testing/methods , Methacrylates/chemistry , Hot Temperature
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