ABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Mycobacterium marinum/pathogenicity , Infections , Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections, Nontuberculous/physiopathology , Colitis, Ulcerative/complications , Colitis, Ulcerative/drug therapy , Metabolic Syndrome , InfliximabABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Crohn Disease/drug therapy , Methotrexate/adverse effects , Pneumonia/chemically induced , Crohn Disease/complications , Lymphadenopathy/diagnostic imaging , Pneumonia/diagnosis , Pneumonia/drug therapy , Thorax/diagnostic imaging , Thorax/abnormalities , Granuloma/complications , Granuloma/diagnostic imagingSubject(s)
Antirheumatic Agents/adverse effects , Colitis, Ulcerative/complications , Infliximab/adverse effects , Metabolic Syndrome/complications , Mycobacterium Infections, Nontuberculous/etiology , Mycobacterium marinum/isolation & purification , Opportunistic Infections/etiology , Skin Diseases, Bacterial/etiology , Alcoholism/complications , Antirheumatic Agents/therapeutic use , Antitubercular Agents/therapeutic use , Colitis, Ulcerative/drug therapy , Diabetes Mellitus, Type 2/complications , Disease Susceptibility , Humans , Infliximab/therapeutic use , Male , Middle Aged , Mycobacterium Infections, Nontuberculous/drug therapy , Mycobacterium Infections, Nontuberculous/microbiology , Obesity/complications , Opportunistic Infections/drug therapy , Opportunistic Infections/microbiology , Skin Diseases, Bacterial/drug therapy , Skin Diseases, Bacterial/microbiologyABSTRACT
La acromegalia es un síndrome clínico producido por la secreción excesiva de hormona del crecimiento. Conlleva una gran morbilidad y un aumento significativo de la mortalidad, principalmente por complicaciones cardiovasculares, respiratorias, así como un aumento en la prevalencia del cáncer. La mortalidad se equipara a la de la población general cuando se consigue la curación de la enfermedad, esto es, la normalización analítica de los valores de IGF-I (factor de crecimiento similar a la insulina tipo I) y hormona del crecimiento. No todos los tumores asociados a esta entidad son subsidiarios de programas coste-efectivos para su diagnóstico temprano. La mejor estrategia terapéutica y de seguimiento en estos pacientes es el conocimiento por el médico responsable de la morbimortalidad asociada a esta entidad, adelantándonos en muchos de los casos al curso evolutivo esperable
Acromegaly is a clinical syndrome caused by the excessive production of growth hormone. It is associated with high morbidity and significantly increased mortality, mainly due to cardiovascular and respiratory complications, and cancer. Mortality is reduced to that of the general population following successful treatment, in other words, when insulin-like growth factor (IGF-I) and growth hormone values return to normal levels. Not all tumours associated with this syndrome benefit from cost-effective early diagnosis programmes. An in-depth knowledge on the part of clinicians of the morbidity and mortality associated with acromegaly, allowing them in many cases to anticipate the expected clinical course of the disease, is the best therapeutic and follow-up strategy in these patients
Subject(s)
Humans , Acromegaly/complications , Neoplasms/complications , Growth Hormone/therapeutic use , Growth Hormone/deficiency , Colorectal Neoplasms/epidemiology , Digestive System Neoplasms/epidemiologyABSTRACT
Acromegaly is a clinical syndrome caused by the excessive production of growth hormone. It is associated with high morbidity and significantly increased mortality, mainly due to cardiovascular and respiratory complications, and cancer. Mortality is reduced to that of the general population following successful treatment, in other words, when insulin-like growth factor (IGF-I) and growth hormone values return to normal levels. Not all tumours associated with this syndrome benefit from cost-effective early diagnosis programmes. An in-depth knowledge on the part of clinicians of the morbidity and mortality associated with acromegaly, allowing them in many cases to anticipate the expected clinical course of the disease, is the best therapeutic and follow-up strategy in these patients.
Subject(s)
Acromegaly/complications , Gastrointestinal Neoplasms/etiology , Acromegaly/diagnosis , Acromegaly/therapy , Algorithms , Gastroenterology , HumansABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Pleural Effusion/diagnosis , Pancreatic Fistula/diagnosis , Pancreatitis, Chronic/complications , Dyspnea/etiology , Asymptomatic DiseasesSubject(s)
Pancreatic Fistula/complications , Pancreatitis, Chronic/complications , Pleural Diseases/complications , Pleural Effusion/etiology , Respiratory Tract Fistula/complications , Asymptomatic Diseases , Calcinosis/diagnostic imaging , Calcinosis/etiology , Cholangiopancreatography, Endoscopic Retrograde , Cholangiopancreatography, Magnetic Resonance , Constriction, Pathologic , Humans , Male , Middle Aged , Pancreatic Ducts/pathology , Pancreatic Ducts/surgery , Pancreatic Pseudocyst/etiology , Pancreatitis, Chronic/diagnostic imaging , Pleural Effusion/diagnostic imaging , Stents , Tomography, X-Ray ComputedABSTRACT
Polycystic liver disease (PLD) is a hereditary disease inherited by autosomal dominant trait that occurs as a frequent extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). We report a case of a 59-year-old woman diagnosed with ADPKD associated with PLD. End-stage chronic renal failure with a secondary Budd-Chiari syndrome developed during the patient's clinical course. She underwent combined liver and kidney transplantation, with a successful response over a 9-year follow-up period.
ABSTRACT
Inflammatory pseudotumor (IPT) of the liver is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. We report a case of a 63-year-old man diagnosed of IPT of the liver and followed for 10 years. During the clinical course, he developed a secondary Budd-Chiari syndrome, with a successful response to a transjugular intrahepatic portosystemic shunt over a 5-year follow-up period.
Subject(s)
Budd-Chiari Syndrome/etiology , Granuloma, Plasma Cell/complications , Liver Diseases/complications , Follow-Up Studies , Humans , Male , Middle Aged , Time FactorsABSTRACT
El pseudotumor inflamatorio (PTI) hepático es una entidad rara, de origen desconocido y aunque puede tener apariencia maligna, su naturaleza es benigna. Presentamos el caso de un varón de 63 años diagnosticado de PTI hepático en seguimiento durante 10 años. En su evolución desarrolló un síndrome de Budd-Chiari, con buena respuesta tras la colocación de una derivación porto-sistémica transyugular, a los cinco años (AU)
Inflammatory pseudotumor (IPT) of the liver is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. We report a case of a 63-yearold man diagnosed of IPT of the liver and followed for 10 years. During the clinical course, he developed a secondary Budd-Chiari syndrome, with a successful response to a transjugular intrahepatic portosystemic shunt over a 5-year follow-up period (AU)
Subject(s)
Humans , Male , Middle Aged , Budd-Chiari Syndrome/complications , Budd-Chiari Syndrome/diagnosis , Cholangiocarcinoma/complications , Cholangiocarcinoma/diagnosis , Laparotomy/methods , Laparotomy , Biopsy/methods , Budd-Chiari Syndrome/physiopathology , Budd-Chiari Syndrome/surgery , Budd-Chiari Syndrome , Immunoglobulins/analysis , Immunoglobulins/isolation & purification , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/methodsABSTRACT
Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course who developed perianal fistulas and abscesses successfully treated with infliximab are reported. Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period.