Are young military personnel at a disproportional risk of heat illness?

Heat illnesses (HI) define a continuum of conditions where patients become incapacitated due to uncompensable heat stress. In the military, HI has a significant health, financial and operational burden that requires vigilant management. Military training and operations regularly expose personnel to known HI risk factors, meaning that prevalence remains high despite stringent attempts to reduce risk to as low as reasonably practicable. While prepubertal children and elderly adults are widely demonstrated to be at greater risk of classic HI than young adults due to impaired physiological and/or behavioural thermoregulation, in military personnel, it is young recruit-age individuals (16-19 years) who consistently experience the highest prevalence of exertional HI. Mechanistically, controlled laboratory studies have never directly compared thermoregulation between young recruit-age individuals and other groups of adults, though research highlighting impaired thermoregulation in prepubertal children potentially has some relevance to late-developing young recruit-age personnel. Aside from potential age-related differences in thermoregulation, a major consideration must also be given to the increased prevalence of organisational risk factors for HI in younger military personnel (eg, education, physical load, rank, job roles), which is likely to be the primary explanation behind age-related trends in HI prevalence, at least in the military. The aims of this article are to review: (i) the epidemiology of HI between young recruit-age individuals and older military personnel; (ii) the theoretical basis for age-associated differences in thermoregulatory function and (iii) pertinent areas for future research.

On the real-time prevention and monitoring of exertional heat illness in military personnel.

The proliferation of user-friendly low-cost wearable sensors has brought the concept of real-time physiological monitoring for exertional heat illness to the cusp of reality. This paper reviews and discusses the current state of the art in real-time physiological status monitoring for exertional heat illness mitigation within the military context. The review examines how both advanced sensor systems, models and algorithms are being combined in an international and collaborative way and how this is providing real solutions to military units to reduce the risk held by the commander. This paper provides additional detail into the process of integrating physiological status monitoring into military training, it explores the development of on-body sensors, the algorithms that can provide actionable information, the process of planning and dynamic risk assessment and describes some of the physiological monitoring systems that are currently being developed by the representative nations. It then discusses the knowledge gaps of how the technology will be integrated into military training, the importance of meaningful, accurate information that is both sensitive and specific and further developing the accuracy of the algorithms and models that are being employed. Finally, it talks about future direction and how individualizing physiological status monitoring can lead to performance enhancement in the form of individualized heat acclimatization programs. In conclusion, physiological status monitoring is at a stage of transition and integration where it can be used effectively to manage and reduce exertional heat illness to enable military personnel to train hard-train safe.

Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status.

PURPOSE: Heat adaptation (HA) is critical to performance and health in a hot environment. Transition from short-term heat acclimatisation (STHA) to long-term heat acclimatisation (LTHA) is characterised by decreased autonomic disturbance and increased protection from thermal injury. A standard heat tolerance test (HTT) is recommended for validating exercise performance status, but any role in distinguishing STHA from LTHA is unreported. The aims of this study were to (1) define performance status by serial HTT during structured natural HA, (2) evaluate surrogate markers of autonomic activation, including heart rate variability (HRV), in relation to HA status. METHODS: Participants (n = 13) were assessed by HTT (60-min block-stepping, 50% VO2peak) during STHA (Day 2, 6 and 9) and LTHA (Day 23). Core temperature (Tc) and heart rate (HR) were measured every 5 min. Sampling for HRV indices (RMSSD, LF:HF) and sympathoadrenal blood measures (cortisol, nephrines) was undertaken before and after (POST) each HTT. RESULTS: Significant (P < 0.05) interactions existed for Tc, logLF:HF, cortisol and nephrines (two-way ANOVA; HTT by Day). Relative to LTHA, POST results differed significantly for Tc (Day 2, 6 and 9), HR (Day 2), logRMSSD (Day 2 and Day 6), logLF:HF (Day 2 and Day 6), cortisol (Day 2) and nephrines (Day 2 and Day 9). POST differences in HRV (Day 6 vs. 23) were + 9.9% (logRMSSD) and - 18.6% (logLF:HF). CONCLUSIONS: Early reductions in HR and cortisol characterised STHA, whereas LTHA showed diminished excitability by Tc, HRV and nephrine measures. Measurement of HRV may have potential to aid real-time assessment of readiness for activity in the heat.

The gonadotrophic response of Royal Marines during an operational deployment in Afghanistan.

Military training has been associated with changes in the hypothalamic-pituitary-gonadal axis consistent with central hypogonadism. Often such changes have been associated with body mass loss, though sleep deprivation and other psychological stress may also contribute. The effects of deployment in a combat zone on the hypothalamic-pituitary-gonadal axis in military personnel are not known. The objective was to investigate the hypothalamic-pituitary-gonadal axis in male military personnel deployed in Afghanistan. Eighty-nine Royal Marines were investigated pre-deployment, following 3 months in Afghanistan and following 2 weeks mid-tour leave. Testosterone, sex hormone-binding globulin (SHBG), follicle-stimulating hormone (FSH), luteinising hormone (LH), 17-hydroxyprogesterone, androstenedione (AD) and insulin were assayed and body mass recorded. The results showed that body mass (kg) dropped from 83.2 ± 9.2 to 79.2 ± 8.2 kg during the first 3 months of deployment (p < 0.001). Total testosterone did not change, but SHBG increased (30.7 ± 9.7 vs. 42.3 ± 14.1 nmol/L, p < 0.001), resulting in a significant (p < 0.001) fall in calculated free testosterone (435.2 ± 138 vs. 375.1 ± 98 pmol/L). Luteinising hormone and FSH increased by 14.3% (p < 0.001) and 4.9% (p = 0.003) respectively. Free testosterone, SHBG, LH and FSH returned to baseline following 2 weeks of mid-tour leave. Androstenedione (AD) decreased by 14.5% (p = 0.024), and insulin decreased by 26% (p = 0.039), over the course of deployment. In this study of lean Royal Marines, free testosterone decreased during operational deployment to Afghanistan. There was no evidence to suggest major stress-induced central hypogonadism. We postulate that reduced body mass, accompanied by a decrease in insulin and AD synthesis, may have contributed to an elevated SHBG, leading to a decrease in free testosterone.

Nutrition research in the military.

Military research performed in an operational environment involves mission-specific considerations. The Institute of Naval Medicine was tasked in 2008 by the Surgeon General to investigate the nutritional status of deployed British military personnel, and how this might affect body composition, physical fitness and operational capability. This paper briefly describes the logistic and technical issues specific to military research that were encountered by the study team, how these issues were overcome and how this research has influenced military practice.