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Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO).

Mylonakis, Eleftherios; Lutaakome, Joseph; Jain, Mamta K; Rogers, Angela J; Moltó, José; Benet, Susana; Mourad, Ahmad; Files, D Clark; Mugerwa, Henry; Kityo, Cissy; Kiweewa, Francis; Nalubega, Mary Grace; Kitonsa, Jonathan; Nabenkema, Evelyn; Murray, Daniel D; Braun, Dominique; Kamel, Dena; Higgs, Elizabeth S; Hatlen, Timothy J; Kan, Virginia L; Sanchez, Adriana; Tierney, John; Denner, Eileen; Wentworth, Deborah; Babiker, Abdel G; Davey, Victoria J; Gelijns, Annetine C; Matthews, Gail V; Thompson, B Taylor; Lane, H Clifford; Neaton, James D; Lundgren, Jens D.

Med ; 3(8): 531-537, 2022 08 12.

Article in English | MEDLINE | ID: mdl-35963234

ABSTRACT

The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.

Subject(s)

COVID-19 Vaccines , COVID-19 , Vaccination , COVID-19/prevention & control , COVID-19/therapy , Humans , Inpatients , Randomized Controlled Trials as Topic , Vaccination/methods

ABSTRACT

Subject(s)

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