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1.
Int J Periodontics Restorative Dent ; 0(0): 1-20, 2024 01 04.
Article in English | MEDLINE | ID: mdl-38175917

ABSTRACT

INTRODUCTION: Tooth extractions can result in alveolar bone dimensional changes, necessitating additional bone grafting for implant placement. Alveolar Ridge Preservation (ARP) aims to counteract post-extraction changes. This study evaluates the bone regenerative properties of a freeze-dried bone allograft (FDBA) and the clinical outcomes of implants in grafted extraction sites. MATERIALS AND METHODS: This case series enrolled 33 patients undergoing single/multiple tooth extractions followed by ARP. Biopsies were harvested during implant placement for histologic and histomorphometric analysis. Clinical outcomes included marginal bone loss and Pink Esthetic Score (PES). RESULTS: 25 patients completed the study. FDBA augmented sockets exhibited new bone formation adjacent to graft particles. Implants (n=25) showed 100% survival and success rates at 1 and 2 years. PES improved significantly over time (p<.001), while marginal bone loss did not significantly differ at 1 and 2 years (p=.096). Specimens showed trabecular bone, residual FDBA particles, and marrow spaces. High magnification revealed immature bone and woven bone bridges around graft particles. No inflammatory cells were observed. CONCLUSIONS: The case series provides valuable insights into ARP performed with FDBA; implants were placed after 3 months of healing without any additional bone augmentation, the histologic outcomes were favorable, and implants were successful after a 2-year period of follow-up.

2.
Int J Periodontics Restorative Dent ; 43(4): e165-e172, 2023.
Article in English | MEDLINE | ID: mdl-37552194

ABSTRACT

Adequate implant primary stability is a key factor to obtain osseointegration and can be measured at insertion by insertion torque (IT) and at different timepoints with resonance frequency analysis (RFA), expressed as an implant stability quotient (ISQ). This retrospective study investigated the correlation between ISQ and IT at implant insertion. All patients who were eligible for this single-cohort retrospective clinical trial were treated with an immediate implant. IT parameters were recorded at implant insertion, and ISQ values were recorded at insertion and at 2-, 4-, and 12-month follow-ups. The study comprised 23 patients who received 32 implants. The mean IT value was 46.87 ± 9.66 Ncm (range: 25 to 65 Ncm), and the mean ISQ value at implant insertion was 71.45 ± 4.24 (range: 63 to 78); these values showed a statistically significant correlation (P < .0001). According to the present data and considering the implant design used in this trial, there is a statistically significant and positive correlation between IT and ISQ values. Thus, ISQ can be used as a reliable method to measure implant stability over time.


Subject(s)
Dental Implantation, Endosseous , Dental Implants , Humans , Dental Implantation, Endosseous/methods , Dental Prosthesis Retention , Osseointegration , Resonance Frequency Analysis , Retrospective Studies , Torque
3.
J Oral Rehabil ; 50(1): 31-38, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36285513

ABSTRACT

BACKGROUND: Temporomandibular disorders (TMDs) are disabling conditions with a negative impact on the quality of life. Their diagnosis is a complex and multi-factorial process that should be conducted by experienced professionals, and most TMDs remain often undetected. Increasing the awareness of un-experienced dentists and supporting the early TMD recognition may help reduce this gap. Artificial intelligence (AI) allowing both to process natural language and to manage large knowledge bases could support the diagnostic process. OBJECTIVE: In this work, we present the experience of an AI-based system for supporting non-expert dentists in early TMD recognition. METHODS: The system was based on commercially available AI services. The prototype development involved a preliminary domain analysis and relevant literature identification, the implementation of the core cognitive computing services, the web interface and preliminary testing. Performance evaluation included a retrospective review of seven available clinical cases, together with the involvement of expert professionals for usability testing. RESULTS: The system comprises one module providing possible diagnoses according to a list of symptoms, and a second one represented by a question and answer tool, based on natural language. We found that, even when using commercial services, the training guided by experts is a key factor and that, despite the generally positive feedback, the application's best target is untrained professionals. CONCLUSION: We provided a preliminary proof of concept of the feasibility of implementing an AI-based system aimed to support non-specialists in the early identification of TMDs, possibly allowing a faster and more frequent referral to second-level medical centres. Our results showed that AI is a useful tool to improve TMD detection by facilitating a primary diagnosis.


Subject(s)
Artificial Intelligence , Temporomandibular Joint Disorders , Humans , Early Diagnosis , Quality of Life , Temporomandibular Joint Disorders/diagnosis , Decision Support Systems, Clinical
4.
Materials (Basel) ; 15(11)2022 May 27.
Article in English | MEDLINE | ID: mdl-35683109

ABSTRACT

The basis for dental implant success comes not only with the titanium implant osseointegration but also depends on other factors such as the development of a soft tissue barrier, which protects the peri-implant bone from the oral environment. The characteristics of surfaces in contact with peri-implant soft tissues may affect the capacity of peri-implant mucosal cells to create a tight seal around the implant, thus influencing long-term implant success. Many histological studies on animals have been conducted on different materials to better understand their influence on peri-implant soft tissues, with the limitation that results from animal studies cannot be fully translated in humans. The aim of this review paper was to analyze the literature focusing on histological clinical studies in humans which have examined different materials or different surface treatments and their effects on peri-implant soft tissues. The research was conducted according to the following PICO question: "Do different implant/abutment materials affect peri-implant soft tissues adhesion and health?". Nine articles were analyzed in this review. The results of this review show the influence of different abutment materials on the peri-implant soft tissues, and the need of further research regarding the effect that abutment materials, surface treatments, and surface properties have on soft tissues.

5.
Children (Basel) ; 9(3)2022 Mar 19.
Article in English | MEDLINE | ID: mdl-35327805

ABSTRACT

Restorative procedures for caries affecting primary molars are a daily challenge for pediatric dentistry, and one of the main factors influencing the results of these restorative procedures is the choice of dental material used: bioactive materials were recently introduced, combining the strength of composites and the benefits of glass ionomers. The present study's objective is to clinically evaluate the aesthetic, functional and biological properties of Activa™ Bioactive composite in approximal and occlusal carious lesions for 1 year using the FDI criteria for evaluating direct dental restorations. Forty-five children with occlusal or approximal caries in first or second primary molars were included in the study: the cavities were then randomized to be restored with either Activa BioActive or SDR Bulk-fill and evaluated over time according to Federation Dentaire Internationale (FDI) criteria. Results showed that Activa BioActive composite has similar performance over time compared to Bulk-fill composite, for both functional and aesthetic properties. Thus, within the limitations of this study, including the short follow-up period, it can be concluded that bioactive materials might be the material of choice to restore primary molars. A longer follow-up period is desirable to confirm these findings.

6.
Clin Implant Dent Relat Res ; 23(1): 86-95, 2021 Feb.
Article in English | MEDLINE | ID: mdl-33295137

ABSTRACT

BACKGROUND: Lateral maxillary sinus augmentation (MSA) is a predictable bone regeneration technique in case of atrophy of the posterior-upper maxilla. Aimed at obtaining quantity and quality of bone suitable for receiving osseointegrated implants, its success is largely due to the skill of the surgeon, but also to the characteristics of the biomaterial used. METHODS: Twenty-four patients needing MSA were included in the study. The patients were randomly allocated to three different groups: anorganic bovine bone mineral as control, tricalcium phosphate with or without hyaluronic acid (HA) as test groups. Nine months after MSA, bone biopsies were harvested for the histomorphometric analysis. Secondary outcomes were mean bone gain, intraoperative and postoperative complications, implant insertion torque, implant failure, and patient-reported outcome measures. RESULTS: Although the percentage of new bone was not statistically different between the three groups (P = .191), the percentages of residual biomaterial was significantly higher (P < .000) and nonmineralized tissue significantly lower (P < .000) in the control than in the test groups. Test groups did not differ significantly from each other for all histomorphometric parameters. The implant insertion torque was significantly higher in the control group (P < .0005). The rest of the secondary outcomes were not significantly different between the groups. CONCLUSION: MSA is a safe and predictable procedure in terms of histological, clinical, and PROAMs, regardless of the biomaterial used. The addition of HA did not influence the outcomes.


Subject(s)
Bone Substitutes , Sinus Floor Augmentation , Animals , Bone Transplantation , Cattle , Dental Implantation, Endosseous , Humans , Maxilla/surgery , Maxillary Sinus/surgery , Patient Reported Outcome Measures
7.
Oral Dis ; 27(4): 1042-1051, 2021 May.
Article in English | MEDLINE | ID: mdl-32790913

ABSTRACT

OBJECTIVES: A controlled, single-blind, randomized clinical trial was performed to evaluate usefulness of antibiotics in preventing pain and complications after tooth extractions and benefits of probiotics in reducing gastro-intestinal symptoms associated with antibiotic therapy. MATERIALS AND METHODS: A total of 159 patients were enrolled in this trial. After tooth extractions, patients were allocated to one of the groups: group 1 received postoperatively amoxicillin + clavulanic acid; group 2 received the same antibiotic therapy with an adjunctive probiotic treatment; and group 3 received neither antibiotics nor probiotics. Follow-up visits were planned at 7, 14, and 21 days after tooth extractions (T1, T2, and T3), and parameters assessed were pain, presence of abscess, edema, fever, alveolitis, trismus, pain, difficulty in daily routine activities, and gastro-intestinal symptoms. RESULTS: The number of patients reporting pain at T1 was significantly higher in the control group when compared to group 2 (p = .016), while no difference for pain intensity was observed between groups. No surgical site infection was observed in any of the groups. Intestinal symptoms seemed to be tackled by probiotic administration. CONCLUSIONS: Pain was the most important symptom in the control group. Antibiotics were not necessary after non-impacted tooth extractions, and probiotics can reduce gastro-intestinal symptoms associated with antibiotics.


Subject(s)
Probiotics , Tooth, Impacted , Anti-Bacterial Agents/therapeutic use , Humans , Molar, Third , Probiotics/therapeutic use , Single-Blind Method , Surgical Wound Infection , Tooth Extraction/adverse effects
8.
Int J Prosthodont ; 33(5): 553-564, 2020.
Article in English | MEDLINE | ID: mdl-32956437

ABSTRACT

PURPOSE: To systematically review the literature comparing marginal bone loss (MBL) and pink esthetic scores of implants with convergent or concave transmucosal profiles vs divergent or parallel profiles. MATERIALS AND METHODS: A PICO question was defined, and an electronic search was carried out in the MEDLINE/PubMed and Cochrane Oral Health Group databases. Studies documenting type of transmucosal profile (either tissue-level profiles or abutments) and soft and/or hard tissue outcomes of implants were considered eligible. Studies were selected on the basis of the inclusion criteria and quality assessments. A meta-analysis with subgroup analyses was performed. RESULTS: Five papers fulfilled the inclusion criteria, and four were eligible for meta-analysis. Significantly less MBL was found in concave/convergent groups, with a mean difference of 0.772 (95% confidence interval [CI]: 0.450 to 1.095; P < .001). In the subgroup analyses for platform-switching and platform-matching connections, a significant effect in favor of concave/convergent was detected, with a standardized difference in means of 1.135 (95% CI: 0.688 to 1.583, P < .001) when platform switching was considered. No significant effects were found for platform-matching connections. CONCLUSION: Within the limitations of this review, it is suggested that concave/convergent implant transmucosal profiles result in less MBL. No statistically significant results were obtained for soft tissue-related outcomes or for the platform-matching connection subgroup.


Subject(s)
Alveolar Bone Loss , Dental Implants , Dental Abutments , Dental Implantation, Endosseous , Esthetics, Dental , Humans
9.
Stud Health Technol Inform ; 270: 1201-1202, 2020 Jun 16.
Article in English | MEDLINE | ID: mdl-32570579

ABSTRACT

Literature reviews are crucial in the choice of the best personalized material type and restauration type in restorative dentistry. We developed an IBM-Watson based system to support literature search for restorative dentistry, and compared its results to a literature search performed by a trained professional. We found that our system could assist the researcher in performing a literature review, but the grounding semantic model needs to be refined in order to provide more extensive results.


Subject(s)
Dentistry
10.
Minerva Stomatol ; 69(5): 295-301, 2020 Oct.
Article in English | MEDLINE | ID: mdl-32407061

ABSTRACT

BACKGROUND: Dental implants placed in medically compromised patients have predictable outcomes and a high rate of survival, compared to those placed in healthy patients. The aims of this study were to observe and compare implant survival/success rates and soft tissue response to tissue-level implants placed in healthy and medically compromised patients with a 1-year follow-up. METHODS: Seventy-two patients, 36 healthy patients (20 females and 16 males) and 36 medically compromised patients (18 females and 18 males) affected by cardiovascular diseases (arrythmia, hypertension, atrial fibrillation, bypass and pacemaker surgery), depression, endocrine metabolic diseases (hypercholesterolemia, type II diabetes, Hashimoto's thyroiditis), gastrointestinal diseases (gastritis, hiatal hernia, gastric ulcers), asthma, osteoporosis or glaucoma received one tissue-level implant. Measurements for primary and secondary outcomes were collected immediately after implant placement and at 1 year from implant insertion. RESULTS: Three were failed and two were survived out of a total of 72 implants. Among healthy patients, two implants failed while one was classified as survived; among Medically compromised patients one implant failed and another one was classified as survived. No statistically significant difference was found between the two groups in terms of success rate or survival rate. No statistically significant differences between the two groups' marginal bone level was observed. In healthy patients a mean loss of keratinized tissue (-0.1±0.6 mm) was reported, while in medically compromised patients a mean gain was reported (+0.5±0.8 mm). CONCLUSIONS: In terms of success, failure and survival rates, tissue level implants placed in healthy and in medically compromised individuals showed no short-term (1 year) differences.


Subject(s)
Alveolar Bone Loss , Dental Implants , Diabetes Mellitus, Type 2 , Alveolar Bone Loss/surgery , Dental Implantation, Endosseous , Dental Prosthesis, Implant-Supported , Dental Restoration Failure , Female , Follow-Up Studies , Humans , Male , Treatment Outcome
11.
Oral Dis ; 26(5): 967-973, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32027441

ABSTRACT

OBJECTIVE: The purpose of this retrospective study was to assess the influence of antibiotics on the development of alveolitis after tooth extractions. MATERIALS AND METHODS: The study population consisted of patients who had erupted tooth extractions in 3 centers. The patients' medical records were collected for several parameters. Moreover, use of antibiotics was evaluated. The primary outcome was the development of alveolitis during the postoperative period. The secondary outcome measure was the possible associations between alveolitis and other patients' characteristics. RESULTS: A total of 1579 patient charts were screened. The patients enrolled in the study were 418 (159 males and 259 females). Alveolitis was reported for 12 extraction sites (2.87%). Six were in the group of patients that received antibiotics (2.14% out of 280 patients treated with antibiotics), and six were in the group of patients that did not receive antibiotics (4.35% out of 138 patients not receiving antibiotics). None of patient-level parameters showed any significant association with the development of alveolitis. CONCLUSION: In conclusion, this study showed that the use of antibiotics after erupted tooth extractions is not useful in preventing alveolitis. Larger, prospective, and randomized studies are needed before incorporating these findings into the daily clinical practice.


Subject(s)
Anti-Bacterial Agents , Tooth Extraction , Anti-Bacterial Agents/therapeutic use , Female , Humans , Lung Diseases/prevention & control , Male , Prospective Studies , Retrospective Studies , Tooth Extraction/adverse effects
12.
Nanomaterials (Basel) ; 9(12)2019 Dec 09.
Article in English | MEDLINE | ID: mdl-31818019

ABSTRACT

BACKGROUND: Calcium phosphate-based compounds are used to treat dental hypersensitivity (DH). Their long-term clinical behaviour needs further research. This study compared the 24-week effectiveness of Teethmate Desensitizer (TD), a pure tetracalcium phosphate (TTCP) and dicalcium phosphate dihydrate (DCPD) powder/water, to that of Dentin Desensitizer (DD), and Bite & White ExSense (BWE), both of calcium phosphate crystallites. METHODS: A total of 105 subjects were selected. A random table was utilised to form three groups of 35 subjects. DH was evaluated using the evaporative sensitivity, tactile sensitivity tests, and the visual analogue scale (VAS) of pain. Response was recorded before the application of the materials (Pre-1), immediately after (Post-0), at 1 week (Post-1), 4 weeks (Post-2), 12 weeks (Post-3) and 24 weeks (Post-4). The non-parametric distribution was assessed with the Shapiro-Wilk statistical test. Intra-group differences for the six time points were evaluated with the Friedman statistical test and the Kruskal-Wallis test. RESULTS: All the materials decreased DH after 24 weeks in comparison to Pre-1. However, the TTCP/DCPD cement showed the greatest statistical efficiency. CONCLUSIONS: The significant decrease of VAS scores produced by TD in the long term suggest the material as the most reliable in the clinical relief of DH.

13.
Quintessence Int ; 50(6): 448-454, 2019.
Article in English | MEDLINE | ID: mdl-31086853

ABSTRACT

OBJECTIVE: This prospective clinical study evaluated the clinical performance of one-, two- and multi-surface composite resin inlays over a 12-year period on premolars and molars. METHOD AND MATERIALS: One clinician placed 113 indirect composite resin inlays (Signum, Heraeus Kulzer) in 30 patients that were bonded using a three-step bonding system and composite resin luting cement. Evaluations were made at 3 and 12 years by another clinician who was not involved in the placement of the restorations, using the modified US Public Health Service (USPHS) criteria. Data were analyzed using a nonparametric statistical test (Mann-Whitney U test) followed by Bonferroni correction (alpha = .05). RESULTS: Fourteen patients could not be followed, yielding to the follow-up of 99 restorations. After 12 years, compared to the 3-year follow-up, tooth integrity, secondary caries, and sensitivity criteria showed significant change, while other parameters did not show significant difference (P > .05). Parameters such as loss of marginal integrity, loss of restoration integrity, loss of surface polish, and secondary caries received more frequently delta scores. At the 3-year follow-up, the clinical performance of one- or two-surface inlays did not show significant difference from multi-surface ones (P = .6317), but at the 12-year follow-up, the results were more favorable for multi-surface inlays. Overall, the failure rate at 12 years was 12%. CONCLUSIONS: Adhesively bonded indirect composite resin inlays showed acceptable long-term clinical results in terms of function, but surface and margin characteristics changed over time.


Subject(s)
Dental Bonding , Inlays , Composite Resins , Humans , Prospective Studies , Resin Cements
14.
Clin Implant Dent Relat Res ; 20(6): 906-914, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30307130

ABSTRACT

BACKGROUND: Consistent bone changes occur after tooth removal, often compromising the success of implants placed within the socket left to natural healing The long-term effect of ridge preservation on implant outcomes is still unclear. PURPOSE: The aim of the study was to assess success and survival rates of implants placed in extraction sockets, with spontaneous healing, or grafted with cortical porcine bone, or collagenated corticocancellous porcine bone. MATERIALS AND METHODS: Ninety patients in need for a single premolar/molar tooth extraction and an implant treatment were selected for the present study. Patients were randomly distributed among 3 groups: sites that healed naturally (ctrl), or sites that received ridge preservation with either cortical (cort) or collagenated corticocancellous porcine bone (coll). Three months after, all the experimental sites were reentered to insert implants. Marginal bone levels were recorded; soft tissues were analyzed and summarized with the Pink Esthetic Score (PES). Forty-two patients out of 90 (initial cohort study) completed the entire follow-up of 4 years. RESULTS: Cumulative survival and success rates for all implants were 100% at a 4-year evaluation. Mean marginal bone loss (MBL) was 1.14 ± 0.23 mm in the cort group, 1.13 ± 0.29 mm in the coll group, and 1.92 ± 0.07 mm in the ctrl group. There were no significant differences between the 2 grafting materials but MBL was significantly greater in the nongrafted sites (P value < .001). The PES resulted significantly better (9.42 ± 0.75) for the cort group than for the coll group (8.53 ± 1.18) and ctrl group (6.07 ± 1.89) at 4-year evaluation. CONCLUSIONS: Ridge preservation was more effective than natural healing in preserving marginal bone and in achieving better esthetic outcomes around implants 4 years after placement. The cortical porcine bone showed better clinical outcomes than collagenated corticocancellous porcine bone.


Subject(s)
Alveolar Ridge Augmentation/methods , Bone Transplantation , Dental Implantation, Endosseous , Dental Implants, Single-Tooth , Tooth Socket/surgery , Adult , Alveolar Bone Loss/diagnostic imaging , Animals , Female , Follow-Up Studies , Humans , Male , Middle Aged , Radiography, Dental , Swine , Tooth Extraction , Tooth Socket/diagnostic imaging
15.
Dent Mater J ; 37(5): 709-716, 2018 Sep 30.
Article in English | MEDLINE | ID: mdl-30047507

ABSTRACT

We investigated three bulk fill composites (Mat1, Mat2, Mat3) cured by two polywave (Poly1, Poly2) and one monowave (Mono) lamps. We used infrared spectroscopy, nanoindentation and atomic force microscopy to assess degree of conversion (DC), stiffness, and roughness after polishing, respectively. Mat2 exhibited the highest DC with Poly1 and second highest with Mono, however was the less stiff. Both Mat1 and Mat3 showed highest DC with Poly2, while Poly1 scored better than Mono. Mat3 scored better than Mat1 and was the third highest when cured with Poly2. For each composite cured by different lamps the stiffness ranked same as the DC. However, roughness did not correlate with hardness. Absolute stiffness value depends on composite formulation. Polywave lamps work better than monowave but not in all cases, as Mat2 showed higher DC with Mono than with Poly2. However, all lamps guarantee a DC≥50% but Mono for Mat1.


Subject(s)
Curing Lights, Dental , Dental Materials/chemistry , Light-Curing of Dental Adhesives/methods , Composite Resins/chemistry , Elasticity , Hardness , Materials Testing , Microscopy, Atomic Force , Spectrophotometry, Infrared , Surface Properties
16.
Quintessence Int ; 49(6): 445-450, 2018.
Article in English | MEDLINE | ID: mdl-29662973

ABSTRACT

Gingival recessions have multifactorial etiology and are often associated with non-caries cervical lesions. Different surgical techniques have been proposed over the years for their treatment, according to the severity of the recession. A novel technique, called restoration guided creeping attachment (RGCA), for the treatment of combined gingival recession and non-caries cervical lesion is presented. RGCA aims at treating Miller class I and II recessions using a specifically designed composite restoration and a minimally invasive approach. A clinical case describing the technique and forming the basis for further studies is presented. Although the results obtained are encouraging, a wider number of patients and longer follow-ups are needed to assess the reliability of this technique.


Subject(s)
Composite Resins/therapeutic use , Dental Restoration, Permanent/methods , Gingival Recession/therapy , Gingivectomy/methods , Tooth Abrasion/therapy , Combined Modality Therapy , Female , Humans , Incisor , Maxilla , Middle Aged
17.
Dent Mater J ; 37(3): 365-373, 2018 Jun 08.
Article in English | MEDLINE | ID: mdl-29311433

ABSTRACT

We investigated the viscoelastic response of direct and indirect dental restorative composites by the novel technique of AM-FM atomic force microscopy. We selected four composites for direct restorations (Adonis, Optifil, EPH, CME) and three composites for indirect restorations (Gradia, Estenia, Signum). Scanning electron microscopy with micro-analysis was also used to support the results. The mean storage modulus of all composites was in the range of 10.2-15.2 GPa. EPH was the stiffest (p<0.05 vs. all other composites but Adonis and Estenia), while no significant difference was observed between direct and indirect group (p≥0.05). For the loss tangent, Gradia had the highest value (~0.3), different (p<0.05) from Optifil (~0.01) and EPH (~0.04) despite the large coefficient of variation (24%), and the direct composites showed higher loss tangent (p<0.01) than the indirect composites. All composites exhibited minor contrast at the edge of fillers, showing that these are pre-polymerized, as confirmed by EDS.


Subject(s)
Composite Resins/chemistry , Dental Materials/chemistry , Adonis , Elasticity , Materials Testing , Methacrylates , Microscopy, Atomic Force , Microscopy, Electron, Scanning , Polymerization , Polyurethanes , Surface Properties , Viscosity
18.
Clin Implant Dent Relat Res ; 19(4): 750-759, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28508515

ABSTRACT

BACKGROUND: Incorporation of bone substitute material into the extraction socket could minimize the edentulous ridge volume loss or maximize the bone formation within the healing area. PURPOSE: The aim of the study was to test the effectiveness in maintaining the volumetric contour of fresh extraction sockets grafted with or without 2 types of porcine biomaterials and covered with a resorbable barrier. MATERIALS AND METHODS: In the present multi-center single-blind randomized control trial, 55 patients underwent 1-tooth extraction, were surveyed, and randomly allocated to control- (25 sites, nat-group) or test groups (15 sites grafted with pre-hydrated collagenated cortico-cancellous porcine bone, coll-group, and 15 with cortical porcine bone, cort-group). Before extraction, and then 4 months later, contours of the sockets were acquired through a laser scanner, voxelized, and ghosts of each patient were superimposed with a matrix laboratory. Volumetric and area evaluations of the virtual superimposed models were performed with dentascan tools to create a volume of interest extending between the 2 residual teeth. Intra- and inter-group comparisons of the outcomes were performed. Non-parametric tests were applied with a level of significance set at P < .05. RESULTS: Intergroup analysis at 4 months' survey revealed that percentage loss of alveolar ridge volume of the coll-group (28.8% ± 8.8%) and of the cort-group (30.2% ± 7.1%) was significantly lower (P < .0001) than that of the naturally-healing group (46.4% ± 4.1%). No statistically-significant differences in outcomes were observed between the 2 test groups at any of the observation periods. Moreover, tooth position (bicuspids vs molars) seemed to affect neither volume loss nor basal shrinkage. CONCLUSION: At the 4-month analysis both test groups showed reduced bone loss when compared to naturally healing sockets. However, the 2 grafting materials were not able to preserve the alveolar crest, and a reduction close to 30% in the estimates was registered after healing.


Subject(s)
Alveolar Process/diagnostic imaging , Bone Remodeling , Bone Substitutes/therapeutic use , Tooth Extraction/adverse effects , Adult , Aged , Alveolar Process/pathology , Animals , Female , Humans , Male , Middle Aged , Osteogenesis , Radiography, Dental, Digital , Single-Blind Method , Swine , Tooth Socket/diagnostic imaging , Tooth Socket/pathology
19.
J Prosthet Dent ; 117(5): 669-676, 2017 May.
Article in English | MEDLINE | ID: mdl-27881324

ABSTRACT

STATEMENT OF PROBLEM: Both direct and indirect techniques are used for dental restorations. Which technique should be preferred or whether they are equivalent with respect to bacterial adhesion is unclear. PURPOSE: The purpose of this in vitro study was to determine the affinity of bacterial biofilm to dental restorative composite resins placed directly and indirectly. MATERIAL AND METHODS: Five direct composite resins for restorations (Venus Diamond, Adonis, Optifil, Enamel Plus HRi, Clearfil Majesty Esthetic) and 3 indirect composite resins (Gradia, Estenia, Signum) were selected. The materials were incubated in unstimulated whole saliva for 1 day. The biofilms grown were collected and their bacterial cells counted. In parallel, the composite resin surface morphology was analyzed with atomic force microscopy. Both bacterial cell count and surface topography parameters were subjected to statistical analysis (α=.05). RESULTS: Indirect composite resins showed significantly lower levels than direct composite resins for bacterial cell adhesion, (P<.001). No significant differences were observed within the direct composite resins (P>.05). However, within the indirect composite resins a significantly lower level was found for Gradia than Estenia or Signum (P<.01). A partial correlation was observed between composite resin roughness and bacterial adhesion when the second and particularly the third-order statistical moments of the composite resin height distributions were considered. CONCLUSIONS: Indirect dental restorative composite resins were found to be less prone to biofilm adhesion than direct composite resins. A correlation of bacterial adhesion to surface morphology exists that is described by kurtosis; thus, advanced data analysis is required to discover possible insights into the biologic effects of morphology.


Subject(s)
Bacterial Adhesion , Biofilms , Composite Resins/chemistry , Dental Materials/chemistry , Dental Restoration, Permanent/methods , Adonis , In Vitro Techniques , Materials Testing , Methacrylates , Polyurethanes , Surface Properties
20.
Int J Oral Maxillofac Implants ; 31(6): 1397-1406, 2016.
Article in English | MEDLINE | ID: mdl-27861667

ABSTRACT

PURPOSE: This study discussed a 3-year retrospective survey of clinical and esthetic outcomes of immediate implants placed by experienced senior surgeons and residents in implant dentistry. MATERIALS AND METHODS: The retrospective chart review included patients who received single-tooth extraction and immediate implant placement at the Tuscan Stomatology Institute between 2009 and 2011. Treated independent postextraction areas were divided into two groups according to the operator's experience: expert versus nonexpert group. Patient satisfaction with the esthetic aspect, chewing, speaking, comfort, self-esteem, and ease of cleaning were assessed by visual analog scales. Changes in the marginal bone level and parameters describing the changes of the facial soft tissue and in papilla index were assessed. Proper pairwise comparison tests were applied with a significant level α = .05. RESULTS: Of the 60 selected patients, 31 were in the expert group and 29 in the nonexpert group. At the 3-year follow-up, findings attested to a significantly higher bone loss in the nonexpert group (1.74 ± 0.59 mm) than those registered in the expert group (1.34 ± 0.45 mm), with a P value of .0044. The papilla index (PI) appeared very stable in the group of experts, whereas it showed a significant loss throughout the study in patients in the nonexpert group (PI = 2 at 1 year and PI = 1.5 at 3 years). Moreover, significant recessions at the buccal soft tissue were registered for all groups at both check-ups; however, in the expert group, slight soft tissue recession was evident 3 years later (0.58 ± 0.72 mm), whereas the nonexpert group showed greater recession (1.52 ± 0.74 mm). Patients reported higher overall satisfaction when treated by the group of experts (85.2%) than when treated by the nonexperts (81.1%) with P < .0001. CONCLUSION: The findings from this study suggested that immediate implant procedures could be considered a successful and satisfying treatment strategy when strict selection criteria together with a high level of surgical expertise are applied.


Subject(s)
Clinical Competence/standards , Dental Implants, Single-Tooth/standards , Esthetics, Dental , Internship and Residency , Adult , Aged , Alveolar Bone Loss/pathology , Dental Implantation, Endosseous/methods , Female , Follow-Up Studies , Humans , Immediate Dental Implant Loading/methods , Male , Maxilla/surgery , Maxillary Diseases/pathology , Middle Aged , Patient Satisfaction , Retrospective Studies , Tooth Extraction/methods , Tooth Socket/surgery
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