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Balkan Med J ; 37(6): 341-347, 2020 10 23.
Article in English | MEDLINE | ID: mdl-32865382

ABSTRACT

Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for understanding the disease course in children. Methods: A retrospective review of the medical records of pediatric patients aged under 18 years who were confirmed as coronavirus disease-2019 between March 11, and June 23, 2020, and were admitted to our hospitals was conducted. Results: A total of 220 pediatric patients with coronavirus disease-2019 were evaluated, of which 48.2% were boys, with a median age of 10 years, and 9.5% had underlying diseases. Patients were classified according to severity, with the percentages of asymptomatic, mild, moderate, and critical/severe cases determined to be 25.5%, 45%, 26.8%, and 2.7%, respectively. Extracorporeal membrane oxygenation was required in two patients (0.9%) and mechanical ventilation in three (1.4%). Targeted therapies were used in six patients (2.7%), with hydroxychloroquine being the most commonly used agent either alone (one patient) or in combination with favipiravir (five patients). Two patients (0.9%) died, and nine (4.1%) were still hospitalized during the study period. Conclusion: Although the disease course of coronavirus disease-2019 seems to be mild in children, critical illness is significant, and the treatment strategy primarily should consist of supportive care according to our preliminary observations.


Subject(s)
Coronavirus Infections/complications , Coronavirus Infections/therapy , Patient Acuity , Pneumonia, Viral/complications , Pneumonia, Viral/therapy , Adolescent , Amides/therapeutic use , Antimalarials/therapeutic use , Antiviral Agents/therapeutic use , Betacoronavirus , COVID-19 , Child , Child, Preschool , Coronavirus Infections/diagnosis , Extracorporeal Membrane Oxygenation , Female , Humans , Hydroxychloroquine/therapeutic use , Infant , Infant, Newborn , Intensive Care Units, Pediatric , Length of Stay , Male , Pandemics , Pneumonia, Viral/diagnosis , Pyrazines/therapeutic use , Respiration, Artificial , Retrospective Studies , SARS-CoV-2 , Treatment Outcome , Turkey
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