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1.
J Foot Ankle Surg ; 60(3): 535-540, 2021.
Article in English | MEDLINE | ID: mdl-33549424

ABSTRACT

Charcot neuroarthropathy is a debilitating condition that frequently leads to skeletal deformity and pedal ulceration in the insensate foot. Results are often poor and no clear guidelines for surgical management exist. Additionally, amputation rates vary widely making it difficult to accurately inform patients of risks. Few studies have assessed outcomes to identify patients for whom reconstruction is likely to fail. The literature is limited, with small sample sizes and mortality infrequently addressed. We performed a retrospective observational study of patients with Charcot neuroarthropathy to assess overall amputation and mortality rates at 30 days, 1 year, and 3 years postreconstruction and evaluated associated risk factors. Rates of infection, re-ulceration, and return to walking were also assessed. We identified 151 patients over a 5-year period. Demographic and clinical characteristics were collected. Descriptive statistics, Cox proportional hazard model, and logistic regression were used. Overall, 22 (14.6%) patients died, and 23 (15.2%) patients advanced to limb amputation postoperatively. End-stage renal disease, peripheral vascular disease, reconstruction during active phase Charcot process, and reconstruction at the ankle or subtalar joint were all associated with poor outcomes. The risk of mortality was 2.5 times higher in patients with end-stage renal disease, and 3.4 times higher among patients with peripheral vascular disease. Patients with ankle or subtalar joint reconstruction were 70% less likely to return to walking compared to medial column reconstruction. Due to these findings, we suggest that patients with such comorbidities be advised of increased risk for complications including failure to return to walking, amputation, and death.


Subject(s)
Arthropathy, Neurogenic , Diabetic Foot , Plastic Surgery Procedures , Amputation, Surgical , Arthropathy, Neurogenic/surgery , Diabetic Foot/surgery , Humans , Observational Studies as Topic , Retrospective Studies , Survivorship
2.
J Foot Ankle Surg ; 57(3): 494-500, 2018.
Article in English | MEDLINE | ID: mdl-29398510

ABSTRACT

Wound healing problems are the most common complication after open reduction with internal fixation (ORIF) of unstable ankle fractures. The incidence is especially high among elderly patients with medical comorbidities and patients with compromised soft tissues. Minimally invasive plate osteosynthesis (MIPO) might provide a safer alternative to ORIF by preventing extensive soft tissue dissection and preserving the blood supply. We conducted a retrospective review of 44 consecutive patients who had undergone MIPO of unstable ankle fractures. All patients had a minimum 1-year follow-up (mean 82 weeks); 80% were aged ≥60 years, 52% had diabetes, and 45% had a compromised soft tissue envelope. Immediate postoperative radiographs were evaluated for the quality of reduction, and clinical records were analyzed for the complication rate. Good to excellent anatomic reduction was achieved in 89% of the patients. The overall complication rate was 27%, including 25% surgical wound dehiscence, 9% infection, and 11% loss of reduction. No patient experienced nerve injury. Those with a history of ankle fracture dislocation and a compromised soft tissue envelope preoperatively had a significantly greater incidence of surgical wound dehiscence and complications overall compared with those without (p = .016 and p = .035; p = .045 and p = .009, respectively). Peripheral vascular disease was a statistically significant predictor of surgical wound dehiscence (p = .010). The overall complication rate in our study was comparable to that seen in similar populations treated with conventional ORIF. In conclusion, our results suggest that MIPO in high-risk patients is a safe alternative, with predictable outcomes, comparable to those of traditional open techniques.


Subject(s)
Ankle Fractures/surgery , Bone Plates , Fracture Fixation, Internal/methods , Fracture Healing/physiology , Adult , Age Factors , Aged , Ankle Fractures/diagnostic imaging , Cohort Studies , Databases, Factual , Diabetes Mellitus/epidemiology , Diabetes Mellitus/physiopathology , Female , Fracture Fixation, Internal/instrumentation , Humans , Injury Severity Score , Joint Instability/prevention & control , Male , Middle Aged , Minimally Invasive Surgical Procedures/adverse effects , Minimally Invasive Surgical Procedures/methods , Patient Safety , Peripheral Vascular Diseases/epidemiology , Peripheral Vascular Diseases/physiopathology , Postoperative Complications/physiopathology , Postoperative Complications/therapy , Prognosis , Retrospective Studies , Risk Assessment , Sex Factors , Treatment Outcome , Vulnerable Populations
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