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2.
J Eur Acad Dermatol Venereol ; 37(9): 1694-1696, 2023 09.
Article in English | MEDLINE | ID: mdl-37177899

Subject(s)
Dermatology , Medicine , Humans
11.
J Eur Acad Dermatol Venereol ; 34(10): 2208-2215, 2020 Oct.
Article in English | MEDLINE | ID: mdl-32119157

ABSTRACT

Around 2% of cutaneous neoplasms arise in the scalp (scalp tumours: STs). They can be classified as primary STs (epithelial, melanocytic and adnexal) or metastatic (from distal tumours or as a spreading from contiguous structures). This anatomic location is usually poorly examined during dermatological consultations, also due to the presence of the hair cover. Moreover, self-examination of the hair-covered skin is often harder for the patient. The peculiar features of the scalp may explain the worse prognosis of STs compared with neoplasms of other locations. The hair coverage protects the scalp from UV radiations, but due to the complex pathogenesis of STs, they may also develop in younger patients. Until now, STs have been not extensively investigated in the dermatological literature, and most publications are written by otolaryngologists, or by head, neck and plastic surgeons. Thus, dermatologists above all have the opportunity and the task to explore the scalp carefully, with the opportunity to make an early diagnosis, possibly changing the patient's prognosis. The aim of this paper was to review the main STs in order to increase awareness among dermatology specialists.


Subject(s)
Head and Neck Neoplasms , Skin Neoplasms , Face , Head and Neck Neoplasms/diagnosis , Humans , Prognosis , Scalp , Skin Neoplasms/diagnosis
16.
J Eur Acad Dermatol Venereol ; 32(11): 1874-1878, 2018 Nov.
Article in English | MEDLINE | ID: mdl-29869357

ABSTRACT

Onychomatricoma is a rare tumour that derives from the nail matrix and grows within the nail plate. The clinical presentation can mimic many other tumours and conditions, and surgical biopsy and histopathological examination are necessary to confirm the diagnosis. As nail surgery is a painful experience for the patient and sometimes can leave permanent onychodistrophy, more precise preoperative diagnosis is needed to distinguish onychomatricoma from other nail diseases more accurately and to limit surgical interventions. The objective of this study was to evaluate current literature on imaging techniques for the diagnosis of onychomatricoma in order to understand how this technology can help the presurgical diagnosis of this tumour. We searched in the Cochrane Skin Group Specialised library, Medline, Embase and LILACS databases all studies evaluating imaging technique for the diagnosis of onychomatricoma up to February 2018. We found that not only nail dermoscopy, but also reflectance confocal microscopy, optical coherence tomography, ultrasonography and magnetic resonance can be useful in this field.


Subject(s)
Diagnostic Imaging/methods , Nail Diseases/diagnostic imaging , Skin Neoplasms/diagnostic imaging , Dermoscopy/methods , Female , Humans , Magnetic Resonance Imaging/methods , Male , Microscopy, Confocal/methods , Nail Diseases/diagnosis , Nail Diseases/pathology , Rare Diseases , Sensitivity and Specificity , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , Tomography, Optical Coherence/methods , Ultrasonography, Doppler/methods
18.
J Eur Acad Dermatol Venereol ; 32(10): 1638-1644, 2018 Oct.
Article in English | MEDLINE | ID: mdl-29706031

ABSTRACT

Mohs micrographic surgery (MMS) is a good treatment option for epithelial neoplasms, especially when localized in areas where tissue conservation is crucial, such as the nail unit (NU). MMS is a method of radical excision offering high cure rates due to the margin control and functional preservation. Our aim is to provide a review on the use of MMS for the treatment of the most common nail tumours. We revised the current literature on the use of MMS to treat malignant neoplasms (Bowen's disease, squamous cell carcinoma, melanoma, basal cell carcinoma, keratoacanthoma, carcinoma cuniculatum) and benign neoplasms (onychomatricoma and glomus tumour). MMS represents a successful surgical option for nail tumours, firstly in terms of tissue conservation: the NU anatomy is complex and the preservation of the component structures is imperative for its functionality. Secondly, due to the surgical radicality, which is essential not only for the clearing of malignant tumours, but also for benign cases, in order to reduce recurrences. Although a conservative treatment of NU melanoma with MMS has been proposed, in our experience, the conservative approach with functional surgery is a good option for the treatment of non-invasive melanoma (in situ and Ia).


Subject(s)
Carcinoma, Squamous Cell/surgery , Melanoma/surgery , Mohs Surgery , Nail Diseases/surgery , Skin Neoplasms/surgery , Carcinoma, Basal Cell/surgery , Glomus Tumor/surgery , Humans , Keratoacanthoma/surgery
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