Insights into the interaction mechanism of ofloxacin and functionalized nano-polystyrene.

Nano-plastics (NPs), an emerging contaminant in the environment, have a larger specific surface area and can act as a carrier of other contaminants. Thus, insights into the interaction mechanisms between NPs and other pollutants are crucial for the assessment of environmental impacts of NPs in the ecosystems. In this study, the interaction mechanism between NPs and ofloxacin (OFL) were investigated via kinetics, fluorescence quenching, and two-dimensional correlation spectroscopy (2DCOS). The adsorption kinetics of OFL on carboxyl-modified polystyrene (PS-COOH) and amine modified polystyrene (PS-NH2) closely fitted the pseudo-second-order kinetics model (R2 = 0.99). Adsorption kinetics indicated that chemical adsorption is dominant mechanism, and the Fourier Transform Infrared Spectrometer (FT-IR) and X-ray photoelectron spectroscopy (XPS) results showed that the electronic interaction, π-π, and H-binding were also involved in the adsorption process. OFL showed strong fluorescence quenching in the presence of NPs. Stern-Volmer quenching was negatively related with the temperature, which was dominated by the static type of quenching. 2DCOS indicated that the π-π conjugation was dominant in the interaction process, and the interaction process was dependent on the solution pH and salinity. Overall, this work provides new insights into the interaction mechanism of NPs and antibiotics in the aquatic ecosystems.

Does Intraoperative Navigation Improve the Anatomical Reduction of Intracapsular Condylar Fractures?

PURPOSE: Accurate reduction of intracapsular condylar fractures is the key to successful reconstruction of the temporomandibular joint and remains a challenge for oral and maxillofacial surgeons. The aim of the study was to evaluate quantitatively the effect of surgical navigation on the accuracy of reduction of intracapsular fractures. MATERIALS AND METHODS: In this prospective randomized nonblinded controlled clinical trial, patients diagnosed with intracapsular condylar fractures who were scheduled for surgical treatment were included and randomized to open treatment with or without surgical navigation. The primary predictor variable was surgical navigation. The primary outcome variable was the average distance (AD) between preoperative and postoperative computed tomographic measurements. The second outcome variable was the rate of anatomic reduction. The χ2 test and independent-samples t test were used for statistical analyses. RESULTS: Twenty patients (33 sides) with intracapsular condylar fractures were enrolled and treated with open surgery (13 male, 7 female; mean age, 28.65 yr; range, 13 to 54 yr). Of these, 10 patients (16 sides) and 10 patients (17 sides) were treated, respectively, with and without surgical navigation technology. All patients underwent follow-up at 1, 3, 6, and 12 months. The mean AD was 0.5235 mm in the navigation group and 1.170 mm in the control group (P < .001). The rate of anatomic reduction was 93.8% in the navigation group and 88.2% in the control group (P = .58). The results indicated that a more precise reduction was achieved in the navigation group than in the control group. CONCLUSION: According to the study results, the rate of anatomic reduction increased and the ADs decreased in the navigation group compared with the control group. Therefore, surgical navigation could increase the accuracy of reduction during the surgical treatment of intracapsular condylar fractures.

Surgical navigation improves reductions accuracy of unilateral complicated zygomaticomaxillary complex fractures: a randomized controlled trial.

Accurate reduction is the key to successful treatment of bone fractures. Complicated zygomaticomaxillary complex fracture, known as one of the most challenging facial bone fractures, is often hard to achieve an accurate reduction, thus leading to facial deformity. In this study, twenty patients with unilateral complicated zygomaticomaxillary complex fractures were included and randomly divided into experimental and control groups, which is with and without the aid of surgical navigation, respectively. The pre- and postoperative imaging data were collected and then analysed using Geomagic Studio 11 software and Brainlab iPlan CMF 3.0. A more precise reduction was showed in the experimental group according to the measurement results of both software programmes than in the control group. In conclusion, surgical navigation showed great value in performing accurate reductions of complicated zygomaticomaxillary complex fractures and restoring facial contour.

[Complications of supratemporalis approach with scalp coronal incision for orbital-zygomatic fracture].

OBJECTIVE: This study aimed to examine the complications of supratemporalis approach with scalp coronal incision for the treatment of orbital-zygomatic fractures. METHODS: A total of 206 patients with orbital-zygomatic fractures were treated with scalp coronal incision through the supratemporalis approach. The effects and complications of the treatment were analyzed. RESULTS: The degree of fracture of the 206 patients was successfully reduced. The facial morphologies and functions were improved. No facial nerve injury was observed in all of the cases. However, the following complications were noted: fossa introcession in 1 case, forehead scalp pain or paresthesia in 11 cases, incision infection in 1 case, subcutaneous hematoma in 1 case, incision scar in 5 cases, and alopecia in 3 cases. CONCLUSIONS: The supratemporalis approach prevents facial nerve injury and does not increase the frequency of other complications. Therefore, this approach can be applied as a routine and safe procedure in clinical settings. 
.