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1.
Childs Nerv Syst ; 40(2): 327-333, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38224362

ABSTRACT

Spinal cord schistosomiasis is a rare and severe form of schistosomiasis. The prognosis is largely conditioned by early diagnosis and treatment. The authors present a case of spinal cord schistosomiasis complicated by spinal cord compression syndrome. This is the case of a 6-year-old patient who presented with febrile gastroenteritis followed by complete paralysis of both lower limbs of sudden onset following a brief stay in a village setting with notion of multiple baths at a stream. Spinal cord MRI revealed an enlarged spinal cord spanning D10 to D12 with heterogeneous contrast enhancement and a syrinx cavity above the lesion. Biological workup revealed an inflammatory syndrome. Treatment consisted of decompressive laminectomy with biopsy of the lesion and a syringo-subarachnoid shunt. Pathological analysis revealed fragments of central nervous system tissues with an infiltrate composed of lymphocytes, plasmocytes, and macrophages producing granulomatous foci lined with areas of necrosis in addition to a large contingent of polynuclear eosinophils, agglutinating around or covering in some places elongated ovoid structures, with relatively thick eosinophilic shells and presenting a terminal spur. Adjuvant treatment consisted of praziquantel and corticotherapy for 1 month. The evolution showed marked improvement in the neurological deficits. She now walks unassisted and has good sphincter control. Spinal cord schistosomiasis is rare in our context; its diagnosis is difficult. The treatment is both medical and surgical.


Subject(s)
Schistosomiasis , Spinal Cord Compression , Syringomyelia , Child , Female , Humans , Spinal Cord/diagnostic imaging , Spinal Cord/surgery , Spinal Cord/pathology , Schistosomiasis/complications , Schistosomiasis/drug therapy , Schistosomiasis/surgery , Spinal Cord Compression/diagnostic imaging , Spinal Cord Compression/etiology , Spinal Cord Compression/surgery , Syringomyelia/complications , Praziquantel/therapeutic use
2.
J Neurol Sci ; 371: 100-104, 2016 Dec 15.
Article in English | MEDLINE | ID: mdl-27871428

ABSTRACT

BACKGROUND: Reliable data on severe head injury mortality is rarely reported in Sub-Saharan African countries and in Cameroon in particular. It was for this reason that for the first time ever a prospective study was carried out during a one year period in the university hospitals and some selected regional and district hospitals in Cameroon. MATERIALS AND METHODS: All the patients admitted for head injury in the emergency units of the selected hospitals were enrolled and followed up over a period of one month. RESULTS: A total of 2835 consecutive patients were included with a sex ratio M/F=3.7/1. One hundred and seventy nine (179) patients lost to follow up were not included. The mortality rate was 77% in the severe head injury group, 16% in the moderate head injury group and 1% in the mild head injury group. In the group of severely injured patients, the mortality rates were very high in the academic hospitals (Laquintinie Hospital of Douala, General Hospital of Douala, Yaounde Central Hospital, and Yaounde University Hospital; 83%, 83%, 81%, and 73% respectively) and in the Regional Hospital of Garoua (84%). CONCLUSION: Mortality rates associated with head injury remain very high in Cameroon, and this is likely true in many countries across Sub-Saharan Africa. The figures approach the mortality expected in the natural history of the disease. Strategic plans should be taken at the local and national levels as in the case of maternal mortality and HIV infections.


Subject(s)
Craniocerebral Trauma/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Blood Pressure , Cameroon/epidemiology , Child , Craniocerebral Trauma/diagnostic imaging , Craniocerebral Trauma/etiology , Craniocerebral Trauma/therapy , Female , Follow-Up Studies , Glasgow Coma Scale , Hospitals, Teaching , Hospitals, University , Humans , Male , Middle Aged , Prospective Studies , Risk Factors , Tomography, X-Ray Computed , Young Adult
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