ABSTRACT
Blood flow through the umbilical vein was measured with Doppler's technique in 206 pregnant women with normal course of pregnancy. Flow rate index, vein diameter and total blood flow per unit of fetal weigh have been calculated. It was found, that the blood flow rate and umbilical vein diameter increase with the growth of the normal pregnancy.
Subject(s)
Pregnancy/physiology , Umbilical Veins/physiology , Blood Flow Velocity , Female , Humans , Regional Blood FlowABSTRACT
Fetal umbilical artery flow was measured with Doppler ultrasound technique in 206 cases of the uncomplicated pregnancy. Indices A/B and R.I. were calculated. It was shown that vascular resistance in the umbilical artery is decreasing in the normal pregnancy parallel to its development and is manifested by the changes in A/B and R.I. values.
Subject(s)
Blood Circulation/physiology , Pregnancy/physiology , Umbilical Arteries/physiology , Adult , Female , Humans , Pregnancy Trimester, Second , Pregnancy Trimester, Third , Vascular Resistance/physiologyABSTRACT
In this report, we present the cytogenetic findings in 478 patients with Turner syndrome diagnosed in Leuven in the period 1965-1989. The karyotypic anomalies are classified into seven groups: 1) classic, 45,X karyotype (52.1%); 2) mosaic 45,X/46,XX (10.9%); 3) mosaic 45,X/47,XXX and other "super-female" cell lines (4.6%); 4) isochromosomes i(Xq) and i(Xp) (16.1%); 5) ring chromosomes r(X) (4.4%); 6) other structural aberrations of the X chromosome (7.7%); and finally 7) mosaic 45,X/46,XY patients (4%). The most pertinent chromosomal findings are briefly discussed and compared with previous reported surveys on subject.
Subject(s)
Karyotyping , Turner Syndrome/genetics , Belgium , Chromosome Aberrations/diagnosis , Chromosome Aberrations/genetics , Chromosome Disorders , Diseases in Twins/genetics , Female , Genetic Carrier Screening , Humans , Mosaicism/genetics , Turner Syndrome/classification , Turner Syndrome/diagnosisABSTRACT
Selected medical and psychosocial problems in 218 Turner syndrome patients diagnosed at the Leuven Centre for Human Genetics are reported here. Special attention is paid to the associated congenital malformations, the mental performance and the occurrence of psychosocial and/or characterological difficulties. Mental underdevelopment was documented in 50 patients (22.9 per cent) and psychosocial and/or characterological problems in a total of 44 patients (20.2 per cent). This study confirms that in patients with Turner syndrome diagnosis special attention should be drawn to the mental development and psychosocial problems.
Subject(s)
Abnormalities, Multiple/genetics , Intellectual Disability/genetics , Karyotyping , Neurocognitive Disorders/genetics , Turner Syndrome/genetics , Abnormalities, Multiple/diagnosis , Abnormalities, Multiple/psychology , Belgium , Female , Humans , Intellectual Disability/diagnosis , Intellectual Disability/psychology , Intelligence , Neurocognitive Disorders/diagnosis , Neurocognitive Disorders/psychology , Personality Disorders/diagnosis , Personality Disorders/genetics , Personality Disorders/psychology , Turner Syndrome/diagnosis , Turner Syndrome/psychologySubject(s)
ABO Blood-Group System , Blood Group Incompatibility/immunology , Pregnancy Complications, Hematologic/immunology , Blood Group Incompatibility/therapy , Blood Transfusion, Intrauterine , Female , Humans , Immunization , Poland , Pregnancy , Pregnancy Complications, Hematologic/therapy , Rh Isoimmunization/immunology , Rh Isoimmunization/therapySubject(s)
Aorta/physiology , Blood Circulation , Fetus/physiology , Adult , Female , Fetal Monitoring , Humans , Pregnancy , Pregnancy Trimester, Second , Pregnancy Trimester, Third , UltrasonographySubject(s)
Blood Transfusion, Intrauterine , Erythroblastosis, Fetal/therapy , Plasmapheresis , Pregnancy Complications, Hematologic/blood , Rh Isoimmunization/blood , Adult , Combined Modality Therapy , Erythroblastosis, Fetal/etiology , Female , Humans , Infant, Newborn , Pregnancy , Prenatal Care , Rh Isoimmunization/complicationsABSTRACT
PIP: The Omega IUD was used as a prosthesis in the uterine cavity for prevention of uterine adhesions in 22 women undergoing reconstructive operations of the uterus (In 9 cases of bicornuate uterus. Strassmann's operation was used and in 13 cases of uterine body myomata, myomectomy was performed). The IUDs remained in the uterine cavity for 3-4 months and were inserted and removed easily. The Omega IUD was very useful in these operations and no complications were observed in connection with their use. (author's modified)^ieng
Subject(s)
Intrauterine Devices , Prostheses and Implants , Uterine Neoplasms/surgery , Uterus/surgery , Adult , Female , Humans , Suture Techniques , Uterus/abnormalitiesSubject(s)
Erythroblastosis, Fetal/prevention & control , Immunization, Passive , Pregnancy Complications, Hematologic/therapy , Rh Isoimmunization/therapy , Antibodies, Anti-Idiotypic/administration & dosage , Female , Humans , Immunoglobulin D/immunology , Infant, Newborn , Isoantibodies , Medication Errors , PregnancyABSTRACT
The results of treatment with intrauterine transfusion are presented. The analysis comprised 48 successful transfusions into 29 foetuses. The reference group consisted of 11 transfusions which proved nonfeasible or ineffective and 54 untreated cases. Following blood treatment, the newborn mortality rate dropped more than threefold. Long-term follow-up of 21 children generally showed their good physical and mental development. We also present 4 cases of supsequent pregnancies after intrauterine blood treatment in a preceding pregnancy, showing that it is possible to save the next baby of the same mother.
Subject(s)
Blood Transfusion, Intrauterine , Erythroblastosis, Fetal/prevention & control , Erythroblastosis, Fetal/complications , Erythroblastosis, Fetal/mortality , Female , Humans , Infant, Newborn , Pregnancy , Rh Isoimmunization/therapyABSTRACT
PIP: Pregnancy tests with the Neo-Prognosticon kit Organon were done in 113 cases and it was found that the test was accurate in 90% of early pregnancy cases. In menstruation disorders caused by other pathological factors in the genital tract, negative results were obtained in all cases. In the diagnosis of extrauterine pregnancy, the results were false negative in only 1 of 16 cases. The other results agreed with the clinical condition of the observed patients. (author's modified)^ieng
