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1.
Chinese Journal of Traumatology ; (6): 308-310, 2017.
Article in English | WPRIM (Western Pacific) | ID: wpr-330396

ABSTRACT

Hypoxia leads to increased red blood cells and blood viscosity at high altitude while moderate trauma increases coagulation in blood. Under the above-mentioned conditions, venous sinus thrombosis is more likely to occur. A patient suffering bilateral acetabular fractures together with the gradual disturbance of consciousness was admitted to our hospital. Though computed tomography arteriogram (CTA) of the brain displayed normal blood vessels; bilateral thalamus and brainstem infarction were found on head computed tomography (CT) and Galen vein thrombosis on cerebral computed tomography venography (CTV). Dehydration and tracheotomy were immediately conducted with antiplatelet, anticoagulant and neurotrophic medicine administered to the patient. After three days' treatment, the patient's consciousness gradually improved and eventually became clear enough to leave the hospital. On follow-up, no dysfunction was documented.

2.
Article in English | WPRIM (Western Pacific) | ID: wpr-316857

ABSTRACT

<p><b>PURPOSE</b>To develop a novel injectable strontium-containing calcium phosphate cement with collagen.</p><p><b>METHODS</b>A novel calcium phosphate bone cement (CPC) was prepared with the addition of strontium element, collagenl, and modified starch; the injectability, solidification time, microstructure, phase composition, compressive strength, anti-collapsibility and histological properties of material were evaluated.</p><p><b>RESULTS</b>The results showed that the material could be injected with an excellent performance; the modified starch significantly improved the anti-washout property of cement; with the liquid to solid ratio of 0.3, the largest compressive strength of cement was obtained (48.0 MPa ± 2.3 MPa); histological examination of repair tissue showed that the bone was repaired after 16 weeks; the degradation of cement was consistent with the new bone growth.</p><p><b>CONCLUSION</b>A novel injectable collagen-strontium-containing CPC with excellent compressive strength and suitable setting time was prepared, with addition of modified starch. The CPC showed a good anti-washout property and the degradation time of the cement met with the new bone growing. This material is supposed to be used in orthopedic and maxillofacial surgery for bone defects.</p>


Subject(s)
Animals , Rabbits , Bone Cements , Chemistry , Therapeutic Uses , Calcium Phosphates , Chemistry , Collagen , Chemistry , Compressive Strength , Histocompatibility Testing , Injections , Strontium , Chemistry
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