Stereotactic Percutaneous Electrochemotherapy as Primary Approach for Unresectable Large HCC at the Hepatic Hilum.

Electrochemotherapy (ECT) is a novel non-thermal ablative technique that combines chemotherapy and the application of electric pulses for reversible cell membrane electroporation. This method was recently performed in the treatment of deep-seated liver tumors during open surgery but experience about percutaneous ECT is rare and further developments like combination of percutaneous ECT with stereotactic navigated devices may be very promising. We report on a case of a 4.7 × 4.5 × 3.5 cm unresectable HCC at the hepatic hilum adjacent to the major vessels and the bile duct that was successfully treated using percutaneous ECT in combination with stereotactic navigation. Follow-up imaging 6 weeks and 6 months after ECT showed complete response.

Effects of television content on physical risk-taking in children.

This study is an investigation of effects of risk-taking by characters in television programs on children's self-reported willingness to take physical risks. Twenty-four boys and 26 girls, ages 6 to 9 years, were assigned to view TV stimulus programs with infrequent physical risk-taking. TV stimulus programs with frequent risk-taking, or no TV stimuli. A self-report measure was used to assess children's willingness to take physical risks in several common injury-relevant situations. Five of the items were administered as a pretest before children watched the stimulus programs and five items were used as a post-test after they viewed the programs. A validation assessment on an independent sample of children indicated that the risk-taking measure was positively correlated with other measures of risk-taking as well as physical injuries. Results indicated that children who viewed the high-risk TV programs increased their self-reported risk-taking significantly more than children in the low-risk TV and no-TV control conditions. Findings are discussed within a theoretical context of observational learning processes, with implications for childhood injury.