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1.
Br J Nutr ; 130(6): 1056-1064, 2023 09 28.
Article in English | MEDLINE | ID: mdl-36627816

ABSTRACT

It is unknown if fibre intake differs across diabetes status in USA adults and is associated with glycaemic outcomes. This cross-sectional analysis utilised National Health and Nutrition Examination Survey cycles 2013-2018 data to estimate usual total dietary fibre intake in USA adults and across diabetes status (no diabetes, prediabetes and type II diabetes (T2D)). Associations among dietary fibre intake and glycaemic outcomes were also reported across groups. Adults (≥ 19 years) with at least one dietary recall were included. Diabetes status was determined from self-report data and measured HbA1c. Independent samples t tests were used to compare mean (se) intake across sub-populations. 14 640 adults (51·3 % female) with 26·4 % and 17·4 % classified as having prediabetes and T2D, respectively. Adults with T2D reported greater mean (se) dietary fibre intake compared with no T2D for females (9·5 (0·13) v. 8·7 (0·11) g/1000 kcal/d and males (8·5 (0·12) v. 7·7 (0·11) g/1000 kcal/d; P < 0·01)). However, only 4·2 (0·50)% and 8·1 (0·90)% of males and females with T2D, respectively, met the adequate intake for fibre. Fibre intake was associated with lower insulin (ß = -0·80, P < 0·01), serum glucose (ß = -1·35, P < 0·01) and Homeostatic Model Assessment for Insulin Resistance (ß = -0·22, P < 0·01) in adults without diabetes, and no relationships in adults with prediabetes or T2D were found. Although dietary fibre intake was highest among adults with T2D, intake was suboptimal across all groups. In adults without diabetes, dietary fibre intake was associated with improved glycaemic outcomes and insulin resistance; however, these associations were attenuated by anthropometric and lifestyle covariates.


Subject(s)
Diabetes Mellitus, Type 2 , Insulin Resistance , Prediabetic State , Male , Humans , Adult , Female , Diabetes Mellitus, Type 2/epidemiology , Prediabetic State/epidemiology , Nutrition Surveys , Blood Glucose/analysis , Cross-Sectional Studies , Dietary Fiber
2.
Nurs Health Sci ; 22(4): 967-976, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32623789

ABSTRACT

Communications media that fails to present information supported by evidence-based practice has the potential to adversely influence knowledge and, ultimately, behaviors. We assessed the immediate effect of a health science documentary on knowledge, attitude, and beliefs among collegiate health sciences students enrolled in an entry-level nutrition course using surveys administered online. Participants (n = 160) completed the pre-survey, watched the documentary What the Health, and immediately completed the post-survey in one setting. Compared with pre-survey scores, participants reported a significant decrease in knowledge, change in attitude to health toward regulation of animal products, and increased agreement with all seven, pre-selected contradictory health claims presented in the documentary. Post-documentary, most participants reported they were planning to make a change in their dietary habits to reflect a plant-based diet. Documentaries providing health information contradictory to the current body of scientific literature are persuasive and can potentially increase negative health behaviors. Inclusion of practices within the health curriculum that encourage, and ultimately, improve health literacy among students before entering the health care workforce is essential.


Subject(s)
Feeding Behavior/psychology , Health Knowledge, Attitudes, Practice , Mass Media/standards , Students, Health Occupations/psychology , Adolescent , Adult , Curriculum/standards , Female , Health Behavior , Humans , Male , Mass Media/statistics & numerical data , Students, Health Occupations/statistics & numerical data , Surveys and Questionnaires
3.
Anticancer Agents Med Chem ; 13(8): 1178-87, 2013 Oct.
Article in English | MEDLINE | ID: mdl-23919747

ABSTRACT

Epidemiological and migratory evidence suggests that dietary soy consumption can lower the risk for breast cancer. The role of soy isoflavones in cancer prevention and promotion is somewhat unclear. There are two views in terms of soy isoflavones and breast cancer. One line of evidence suggests that soy and its isoflavones have exhibited cancer-preventive properties including lengthening the menstrual cycle, altering estrogen metabolism away from cancerous compounds, and demonstrating anti-proliferative properties in vivo. On the contrary, isoflavones found in soy products are suggested to behave as weak estrogens and as such, much speculation surrounds the influence of soy and/or its isoflavones on hormone-receptor-positive cancers. The objective of this review is to present the latest knowledge regarding the role of soy and its isoflavones with the development and advancement of breast cancer, the safety of soy isoflavones for breast cancer survivors, and a comparison of the carcinogenic effects in animal models following soy isoflavone and estrogen administration. This review compares and contrasts literature in terms of the anti-cancer and cancer-promoting effects of soy isoflavones and estrogen in humans and animal models. In conclusion, current human and animal data provide evidence for several anticancer properties of soy and/or its isoflavones. Although the specific quantities and constituents responsible for the observed anti-cancer effects have not been elucidated, it appears that soy isoflavones do not function as an estrogen, but rather exhibit anti-estrogenic properties. However, their metabolism differs between humans and animals and therefore the outcomes of animal studies may not be applicable to humans. The majority of breast cancer cases are hormone-receptor-positive; therefore, soy isoflavones should be considered a potential anti-cancer therapeutic agent and warrant further investigation.


Subject(s)
Breast Neoplasms/prevention & control , Estrogens/metabolism , Glycine max/metabolism , Isoflavones/metabolism , Animals , Asian People , Breast Neoplasms/ethnology , Breast Neoplasms/metabolism , Female , Humans , Isoflavones/pharmacology , Neoplasms, Hormone-Dependent/metabolism , Neoplasms, Hormone-Dependent/prevention & control , Phytoestrogens/metabolism , Phytoestrogens/pharmacology , Glycine max/chemistry , White People
4.
Nutrients ; 2(6): 599-610, 2010 06.
Article in English | MEDLINE | ID: mdl-22254044

ABSTRACT

We compared calcium (Ca) sources and intake, as well as multivitamin/mineral supplement use between female students with nutrition/health background and those from general-student-populations. 314 participants 18-37 y, including 57 African-Americans and 54 Caucasian-Americans recruited from Nutrition and/or other Health Sciences departments (NHS), and 100 African-American and 103 Croatian women representing general-student-population (GSP), completed food frequency questionnaire assessing their usual Ca intake and supplement use. NHS populations met recommendations and consumed significantly more Ca, particularly from dairy sources, and were more likely to take supplements than GSP groups, suggesting that health education may influence Ca intake.


Subject(s)
Calcium, Dietary/administration & dosage , Dietary Supplements/statistics & numerical data , Adolescent , Adult , Croatia/epidemiology , Female , Health Knowledge, Attitudes, Practice , Humans , Nutritional Requirements , Students , Surveys and Questionnaires , United States/epidemiology , Universities , Young Adult
5.
Nutr Res ; 27(4): 194-199, 2007 Apr.
Article in English | MEDLINE | ID: mdl-19081830

ABSTRACT

The objective of this study was to assess the effects of weight history status and ethnicity on the ability of the Harris Benedict (HB) formula to: 1) predict measured resting energy expenditure (REE), and, 2) accurately estimate energy needs over a 2-week test period. Subjects were never-overweight (BMI

6.
Fertil Steril ; 86(2): 411-7, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16762348

ABSTRACT

OBJECTIVE: To test the hypothesis that the dietary intake and dietary composition of women with polycystic ovary syndrome (PCOS) is associated with indices of glycemic status. We hypothesized that women with PCOS would consume a diet higher in total energy, fat, and specific foods with a high glycemic index than would healthy, control-group women and that dietary composition would be associated with indices of insulin resistance and secretion among women with PCOS. DESIGN: Cohort study. SETTING: Research center on a university campus. PATIENT(S): Thirty women with PCOS and 27 healthy, age-, race-, and body mass index (BMI)-matched control women. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Nutrient intake data were collected from a food questionnaire and a 4-day food record. Fasting sera were analyzed for concentrations of insulin and glucose; estimates of insulin resistance were calculated. RESULT(S): Consumption of total energy, macronutrients, micronutrients, and high glycemic index foods was similar between the groups. However, the PCOS group consumed significantly more white bread (7.9 +/- 4.4 vs. 5.5 +/- 2.9 servings over 4 days) and tended to consume more fried potatoes than did the control group (1.0 +/- 1.5 vs. 0.4 +/- 0.7 servings over 4 days). The PCOS group had a significantly greater fasting insulin concentration (22.5 +/- 14.9 vs. 15.1 +/- 8.3 muIU/mL) and a significantly lower glucose-to-insulin ratio (4.7 +/- 2.1 vs. 7.6 +/- 5.2) than the control group. Within the PCOS group, HOMA-IR and HOMA-%beta-cell function were significantly associated with BMI. The HOMA-IR, HOMA-%beta-cell, fasting insulin, and glucose-to-insulin ratio were not positively associated with measures of diet composition. CONCLUSION(S): Compared with matched control women, women with PCOS exhibited a dietary pattern that was marked by consumption of a greater amount of specific foods with a high glycemic index; however, diet composition was not associated with the greater fasting insulin concentration or with lower glucose-to-insulin ratio that was observed in the PCOS group.


Subject(s)
Diet , Polycystic Ovary Syndrome/physiopathology , Adult , Blood Glucose/metabolism , Body Mass Index , Bread , Case-Control Studies , Cohort Studies , Cooking , Fasting/blood , Female , Homeostasis , Humans , Insulin/blood , Insulin/metabolism , Insulin Resistance , Insulin Secretion , Insulin-Secreting Cells/metabolism , Osmolar Concentration , Polycystic Ovary Syndrome/blood , Solanum tuberosum , Surveys and Questionnaires
7.
Fertil Steril ; 85(3): 679-88, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16500338

ABSTRACT

OBJECTIVE: To determine whether eucaloric diets either enriched with monounsaturated fatty acids (MUFA; 17% energy) or low in carbohydrates (Low CHO; 43% energy) would increase insulin sensitivity (Si) and decrease circulating insulin concentrations, relative to a standard diet (STD; 56% CHO, 31% fat, 16% protein), among women with polycystic ovary syndrome (PCOS). DESIGN: Crossover. SETTING: Academic research environment. PATIENT(S): Healthy women with PCOS not on hormonal or insulin-sensitizing therapy. INTERVENTION(S): Subjects consumed three, 16-day, eucaloric diets, each separated by a 3-week washout period. A frequently sampled, intravenous, glucose tolerance test was administered at baseline and following each diet. MAIN OUTCOME MEASURE(S): Fasting glucose, insulin, the acute insulin response to glucose (AIRg), Si, sex hormone-binding globulin (SHBG), dehydroepiandrosterone sulfate (DHEAS), total testosterone (T), free T, A4, total cholesterol, high-density lipoprotein cholesterol (HDL-C), tryglycerides (TG), and free fatty acids (FFA). RESULT(S): Fasting insulin was lower following the Low CHO diet relative to the STD diet; AIRg was lower following the Low CHO diet relative to the MUFA diet. Fasting glucose, Si, and the circulating concentrations of reproductive hormones were not significantly affected by the intervention. CONCLUSION(S): A moderate reduction in dietary carbohydrate reduced the fasting and postchallenge insulin concentrations among women with PCOS, which, over time, may improve reproductive/endocrine outcomes.


Subject(s)
Diet , Dietary Carbohydrates/administration & dosage , Fatty Acids, Monounsaturated/administration & dosage , Insulin Resistance , Insulin/blood , Polycystic Ovary Syndrome/diet therapy , Adult , Body Composition , Cross-Over Studies , Endocrine Glands/physiopathology , Fasting/blood , Female , Glucose/pharmacology , Humans , Osmolar Concentration , Polycystic Ovary Syndrome/blood , Polycystic Ovary Syndrome/metabolism , Polycystic Ovary Syndrome/physiopathology
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