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7.
Case Rep Gastrointest Med ; 2014: 585291, 2014.
Article in English | MEDLINE | ID: mdl-24987537

ABSTRACT

Polycystic liver disease (PLD) is a hereditary disease inherited by autosomal dominant trait that occurs as a frequent extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). We report a case of a 59-year-old woman diagnosed with ADPKD associated with PLD. End-stage chronic renal failure with a secondary Budd-Chiari syndrome developed during the patient's clinical course. She underwent combined liver and kidney transplantation, with a successful response over a 9-year follow-up period.

8.
Rev Esp Enferm Dig ; 105(6): 360-2, 2013 Jul.
Article in English | MEDLINE | ID: mdl-24090020

ABSTRACT

Inflammatory pseudotumor (IPT) of the liver is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. We report a case of a 63-year-old man diagnosed of IPT of the liver and followed for 10 years. During the clinical course, he developed a secondary Budd-Chiari syndrome, with a successful response to a transjugular intrahepatic portosystemic shunt over a 5-year follow-up period.


Subject(s)
Budd-Chiari Syndrome/etiology , Granuloma, Plasma Cell/complications , Liver Diseases/complications , Follow-Up Studies , Humans , Male , Middle Aged , Time Factors
9.
Rev. esp. enferm. dig ; 105(6): 360-362, jul. 2013. ilus
Article in Spanish | IBECS | ID: ibc-115802

ABSTRACT

El pseudotumor inflamatorio (PTI) hepático es una entidad rara, de origen desconocido y aunque puede tener apariencia maligna, su naturaleza es benigna. Presentamos el caso de un varón de 63 años diagnosticado de PTI hepático en seguimiento durante 10 años. En su evolución desarrolló un síndrome de Budd-Chiari, con buena respuesta tras la colocación de una derivación porto-sistémica transyugular, a los cinco años (AU)


Inflammatory pseudotumor (IPT) of the liver is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. We report a case of a 63-yearold man diagnosed of IPT of the liver and followed for 10 years. During the clinical course, he developed a secondary Budd-Chiari syndrome, with a successful response to a transjugular intrahepatic portosystemic shunt over a 5-year follow-up period (AU)


Subject(s)
Humans , Male , Middle Aged , Budd-Chiari Syndrome/complications , Budd-Chiari Syndrome/diagnosis , Cholangiocarcinoma/complications , Cholangiocarcinoma/diagnosis , Laparotomy/methods , Laparotomy , Biopsy/methods , Budd-Chiari Syndrome/physiopathology , Budd-Chiari Syndrome/surgery , Budd-Chiari Syndrome , Immunoglobulins/analysis , Immunoglobulins/isolation & purification , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/methods
10.
World J Gastroenterol ; 19(4): 590-3, 2013 Jan 28.
Article in English | MEDLINE | ID: mdl-23382642

ABSTRACT

Primary sclerosing cholangitis is an infrequent extraintestinal manifestation of ulcerative colitis. Damage to bile ducts is irreversible and medical therapies to prevent progression of the disease are usually ineffective. We describe a patient with long-standing ulcerative colitis, which was refractory to corticosteroid therapy who developed primary sclerosing cholangitis (biochemical stage II/IV) in the course of his pancolitis. Treatment with infliximab (5 mg/kg as an induction dose followed by maintenance doses every two months) was indicated because of steroid-dependent disease associated to primary sclerosing cholangitis as well as sacroiliitis and uveitis and previous episode of severe azathioprine-related hepatic toxicity. At present, after two years of follow-up, the patient is asymptomatic with normal liver tests and complete resumption of daily life activities. This case draws attention to the usefulness of anti-tumor necrosis factor-alpha therapy for the management of primary sclerosing cholangitis as extraintestinal manifestation of inflammatory bowel disease.


Subject(s)
Antibodies, Monoclonal/therapeutic use , Cholangitis, Sclerosing/drug therapy , Colitis, Ulcerative/drug therapy , Drug Resistance , Immunosuppressive Agents/therapeutic use , Steroids/therapeutic use , Aged , Cholangitis, Sclerosing/diagnosis , Cholangitis, Sclerosing/etiology , Colitis, Ulcerative/complications , Colitis, Ulcerative/diagnosis , Humans , Infliximab , Male , Treatment Outcome
11.
Ann Gastroenterol ; 26(3): 261-263, 2013.
Article in English | MEDLINE | ID: mdl-24714219

ABSTRACT

Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course who developed perianal fistulas and abscesses successfully treated with infliximab are reported. Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period.

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