A Prospective Randomized Controlled Two-Arm Clinical Study Evaluating the Efficacy of a Bioelectric Dressing System for Blister Management in US Army Ranger Recruits.

This study focused on a clinically relevant healthcare problem in the military: acute soft tissue wounds, or blisters. The trial was a prospective, controlled, randomized two-arm study evaluating the efficacy of a bioelectric dressing, Procellera®, applied topically two to three times per week for 2 weeks to blisters developed in Ranger trainees during training at Fort Benning, Georgia. A total of 80 US Army Ranger recruits with blister wounds below the knee were randomly assigned to one of two treatment groups (n = 40/group). The primary goal was to assess the clinical efficacy (rate of healing) of administered Procellera in conjunction with the standard-of-care (SOC) treatment, moleskin and Tegaderm ®, on the healing rate of blisters compared with the SOC treatment alone. The secondary end points for efficacy were the quantities of wound fluid biomarkers and bacterial bioburden. The tertiary end point was assessment of pain in the treatment group compared with that of the control group during the 2-week study. The results showed no statistical difference between the SOC and SOC+Procellera groups in wound healing and pain. Wound fluid was reported for 24 participants (64.9%) in the SOC group and 21 participants (56.8%) in SOC+Procellera group at the baseline measurement (ρ = .475); however, the wounds were devoid of fluid on follow-up visits. The mild nature of the wounds in this study was apparent by the low pain scores at the beginning of the study, which disappeared by the follow-up visits. The average wound sizes were 2.2cm2 and 1.5cm2 for the SOC and SOC+Procellera groups, respectively. This trial protocol should be conducted on open softtissue wounds in severe heat. To our knowledge, this is the first clinical study conducted within the US Army Rangers training doctrine.

Immediate and long-term effects of a sophomore radiology elective.

RATIONALE AND OBJECTIVES: The purpose of this study was to determine the influence of sophomore electives in radiology on medical students' career choices and later clinical practice as physicians and to assess the need for change in the curriculum. MATERIALS AND METHODS: A survey questionnaire created by the Department of Radiology was sent to graduates of the Chicago Medical School, North Chicago, Ill, who had been offered a series of three sophomore electives in radiology between academic years 1978 and 1998. The survey included five questions concerning the utility of the electives. RESULTS: Of the 2,883 questionnaires mailed, 31 were undeliverable and 411 (14%) were completed and returned. A total of 347 (84%) of the respondents had enrolled in one or more of the sophomore radiology electives, and 325 of 340 (96%) stated that the instruction received was valuable to their careers. In addition, 54 of 333 respondents (16%) indicated that the radiology electives influenced their choice of specialty, and 322 of 328 (98%) believed that the courses should remain part of the sophomore year elective choices. Within the respondent pool, 40 of 261 (15%) identified themselves as radiologists. Among radiologists and nonradiologists, respectively, 39 of 40 (98%) and 308 of 371 (83%) had enrolled in one or more of the sophomore electives in radiology, 34 of 39 (87%) and 291 of 301 (97%) stated that knowledge gained from the courses proved valuable to their careers, 30 of 39 (77%) and 24 of 303 (8%) were influenced by the electives in their choice of specialty, and 37 of 39 (95%) and 285 of 289 (99%) stated that radiology should continue to be offered during the sophomore year. CONCLUSION: Practicing physicians overwhelmingly supported the continuation of the sophomore radiology electives. Some suggested that radiology should be a required course or clinical clerkship.