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1.
Aerosol Sci Technol ; 57(3): 233-254, 2023 Jan 19.
Article in English | MEDLINE | ID: mdl-37213938

ABSTRACT

At the beginning of the COVID-19 pandemic, the primary route of transmission of the SARS-CoV-2 virus was not well understood. Research gathered from other respiratory infectious diseases, including other coronaviruses, was the basis for the initial perceptions for transmission of SARS-CoV-2. To better understand transmission of SARS-CoV-2, a rapid literature review was conducted from literature generated March 19, 2020, through September 23, 2021. 18,616 unique results were identified from literature databases and screened. Of these, 279 key articles were reviewed and abstracted covering critical topics such as environmental/workplace monitoring, sampling and analytical method evaluation, and the ability of the virus to remain intact and infectious during sampling. This paper describes the results of the rapid literature review, which evaluated pathways that contribute to transmission as well as the strengths and limitations of current sampling approaches. This review also evaluates how different factors, including environmental conditions and surface characteristics, could impact the transmission potential of SARS-CoV-2. A continual rapid review in the midst of a pandemic proved particularly useful for quickly understanding the transmission parameters of the virus and enabled us to comprehensively assess literature, respond to workplace questions, and evaluate our understanding as the science evolved. Air and surface sampling with the accompanying analytical methods were not generally effective in recovering SARS-CoV-2 viable virus or RNA in many likely contaminated environments. In light of these findings, the development of validated sampling and analysis methods is critical for determining worker exposure to SARS-CoV-2 and to assess the impact of mitigation efforts.

2.
Ind Health ; 58(5): 467-478, 2020 Oct 08.
Article in English | MEDLINE | ID: mdl-32321887

ABSTRACT

From 2011-2015, the National Institute for Occupational Safety and Health Nanotechnology Field Studies Team conducted 11 evaluations at worksites that either produced engineered nanomaterials (ENMs) via a wet process or used ENMs in a wetted, suspended, or slurry form. Wet handling or processing of ENMs reduces potential exposure compared to dry handling or processing; however, air sampling data indicated exposures may still occur. Information was gathered about each company, production processes, ENMs of interest, and control measures. Exposure assessments included air sampling using filter media, surface wipe sampling, and real-time particle counting by direct-reading instruments. Electron microscopy analysis of air filters confirmed the presence of ENMs of interest (10 of 11 sites). When a method was available, chemical analysis of filters was also used to detect the presence of ENMs (nine of 11 sites). Wipe samples were collected at four of the 11 sites, and, in each case, confirmed the presence of ENMs on surfaces. Direct-reading data showed potential nanomaterial emissions (nine of 11 sites). Engineering controls included fume hoods, cleanrooms, and enclosed processes. Personal protective equipment was required during all 11 evaluations. Recommendations to address potential exposures were provided to each company following the hierarchy of controls.


Subject(s)
Nanostructures/analysis , Occupational Exposure/analysis , Particulate Matter/analysis , Air Pollutants, Occupational/analysis , Environmental Monitoring/methods , Microscopy, Electron , Nanostructures/ultrastructure , Nanotechnology , National Institute for Occupational Safety and Health, U.S. , Occupational Exposure/prevention & control , Personal Protective Equipment , United States
3.
J Nanopart Res ; 22(2)2020 May 08.
Article in English | MEDLINE | ID: mdl-34552386

ABSTRACT

Recent studies have shown that high concentrations of ultrafine particles can be emitted during the 3D printing process. This study characterized the emissions from different filaments using common fused deposition modeling printers. It also assessed the effectiveness of a novel engineering control designed to capture emissions directly at the extruder head. Airborne particle and volatile organic compound concentrations were measured, and particle emission rates were calculated for several different 3D printer and filament combinations. Each printer and filament combination was tested inside a test chamber to measure overall emissions using the same print design for approximately 2 h. Emission rates ranged from 0.71 × 107 to 1400 × 107 particles/min, with particle geometric mean diameters ranging from 45.6 to 62.3 nm. To assess the effectiveness of a custom-designed engineering control, a 1-h print program using a MakerBot Replicator+ with Slate Gray Tough polylactic acid filament was employed. Emission rates and particle counts were evaluated both with and without the extruder head emission control installed. Use of the control showed a 98% reduction in ultrafine particle concentrations from an individual 3D printer evaluated in a test chamber. An assessment of the control in a simulated makerspace with 20 printers operating showed particle counts approached or exceeded 20,000 particles/cm3 without the engineering controls but remained at or below background levels (< 1000 particles/cm3) with the engineering controls in place. This study showed that a low-cost control could be added to existing 3D printers to significantly reduce emissions to the work environment.

4.
Ann Work Expo Health ; 2018 Feb 23.
Article in English | MEDLINE | ID: mdl-29529138

ABSTRACT

Control banding (CB) has been widely recommended for the selection of exposure controls for engineered nanomaterials (ENMs) in the absence of ENM-specific occupational exposure limits (OELs). Several ENM-specific CB strategies have been developed but have not been systematically evaluated. In this article, we identify the data inputs and compare the guidance provided by eight CB tools, evaluated on six ENMs, and assuming a constant handling/use scenario. The ENMs evaluated include nanoscale silica, titanium dioxide, silver, carbon nanotubes, graphene, and cellulose. Several of the tools recommended the highest level of exposure control for each of the ENMs in the evaluation, which was driven largely by the hazard banding. Dustiness was a factor in determining the exposure band in many tools, although most tools did not provide explicit guidance on how to classify the dustiness (high, medium, low), and published data are limited on this topic. The CB tools that recommended more diverse control options based on ENM hazard and dustiness data appear to be better equipped to utilize the available information, although further validation is needed by comparison to exposure measurements and OELs for a variety of ENMs. In all CB tools, local exhaust ventilation was recommended at a minimum to control exposures to ENMs in the workplace. Generally, the same or more stringent control levels were recommended by these tools compared with the OELs proposed for these ENMs, suggesting that these CB tools would generally provide prudent exposure control guidance, including when data are limited.

5.
J Occup Environ Hyg ; 15(1): 44-56, 2018 01.
Article in English | MEDLINE | ID: mdl-29053929

ABSTRACT

OBJECTIVE: Toxicology studies suggest that exposure to certain types of engineered nanomaterials (ENMs) may cause adverse health effects, but little is known about the workforce in the United States that produces or uses these materials. In addition, occupational exposure control strategies in this industry are not well characterized. This study identified U.S. ENM manufacturers and users (other than carbon nanotubes and nanofibers, which have been characterized elsewhere), determined workforce size, characterized types and quantities of materials used, occupational exposure control strategies, and the feasibility of occupational ENM exposure studies. METHODS: Eligible companies were identified and information was collected through phone surveys on nanomaterials produced or used, workforce size, location, work practices, and exposure control strategies. The companies were classified into groups for additional examinations. RESULTS: Forty-nine companies producing or using ENMs in the U.S. were identified. These companies employed at least 1,500 workers. Most companies produced or used some form of nanoscale metal. More than half of the eligible companies were suppliers for the coatings, composite materials, or general industries. Each company provided information about worker exposure reduction strategies through engineering controls, administrative controls, or personal protective equipment. Production-scale companies reported greater use of specific exposure control strategies for ENMs than laboratory-scale companies. CONCLUSIONS: Workplaces producing or using ENMs report using engineering and administrative controls as well as personal protective equipment to control worker exposure. Industrywide exposure assessment studies appear feasible due to workforce size. However, more effort must be taken to target industries using specific ENMs based on known toxicological effects and health risks.


Subject(s)
Manufacturing and Industrial Facilities/statistics & numerical data , Nanostructures/statistics & numerical data , Occupational Exposure/analysis , Occupational Exposure/prevention & control , Humans , Metals , Occupational Health/statistics & numerical data , Personal Protective Equipment , United States , Workforce , Workplace
6.
J Nanopart Res ; 182017 Aug.
Article in English | MEDLINE | ID: mdl-29056867

ABSTRACT

This site study was conducted in a chemical laboratory to evaluate nanomaterial emissions from 20-30 nm diameter bundles of single-walled carbon nanotubes (CNTs) during product development activities. Direct-reading instruments were used to monitor the tasks in real time and airborne particles were collected using various methods to characterize released nanomaterials using electron microscopy and elemental carbon (EC) analyses. CNT clusters and a few high aspect ratio particles were identified as being released from some activities. The EC concentration at the source of probe sonication was found to be higher than other activities including weighing, mixing, centrifugation, coating and cutting. Various sampling methods all indicated different levels of CNTs from the activities, however, the sonication process was found to release the highest amounts of CNTs. It can be cautiously concluded that the task of probe sonication possibly released nanomaterials into the laboratory and posed a risk of surface contamination. Based on these results, the sonication of CNT suspension should be covered or conducted inside a ventilated enclosure with proper filtration or a glovebox to minimize the potential of exposure.

7.
MMWR Morb Mortal Wkly Rep ; 66(37): 986-989, 2017 Sep 22.
Article in English | MEDLINE | ID: mdl-28934187

ABSTRACT

In July 2015, a municipal health department in Ohio received complaints of respiratory and ocular symptoms from patrons of an indoor waterpark resort. In response, the health department conducted an online survey in August 2015 through which 19 (68%) patron and employee respondents reported eye burning, nose irritation, difficulty breathing, and vomiting. On August 11, 2015, the health department requested a health hazard evaluation by CDC's National Institute for Occupational Safety and Health to characterize the prevalence of symptoms among employees and determine the etiology of work-related symptoms. In January 2016, CDC investigators performed a cross-sectional epidemiologic study, environmental sampling, and ventilation system assessment (1). Findings suggested that chlorine disinfection byproducts and environmental conditions contributed to a higher prevalence of work-related respiratory and ocular symptoms among employees in the waterpark compared with employees in other resort areas. Recommendations included servicing the ventilation system, changing work practices to decrease the amount of disinfection byproduct precursors, and responding promptly to employee reports of symptoms.


Subject(s)
Air Pollution, Indoor/adverse effects , Chlorine/adverse effects , Eye Diseases/epidemiology , Occupational Diseases/epidemiology , Occupational Exposure/adverse effects , Respiratory Tract Diseases/epidemiology , Swimming Pools , Adolescent , Adult , Aged , Air Pollution, Indoor/analysis , Chlorine/analysis , Cross-Sectional Studies , Eye Diseases/etiology , Female , Humans , Male , Middle Aged , Occupational Diseases/etiology , Occupational Exposure/analysis , Ohio/epidemiology , Prevalence , Respiratory Tract Diseases/etiology , Ventilation , Young Adult
8.
J Nanopart Res ; 172015 Nov.
Article in English | MEDLINE | ID: mdl-26705393

ABSTRACT

The evaluation of engineering controls for the production or use of carbon nanotubes (CNTs) was investigated at two facilities. These controls assessments are necessary to evaluate the current status of control performance and to develop proper control strategies for these workplaces. The control systems evaluated in these studies included ventilated enclosures, exterior hoods, and exhaust filtration systems. Activity-based monitoring with direct-reading instruments and filter sampling for microscopy analysis were used to evaluate the effectiveness of control measures at study sites. Our study results showed that weighing CNTs inside the biological safety cabinet can have a 37% reduction on the particle concentration in the worker's breathing zone, and produce a 42% lower area concentration outside the enclosure. The ventilated enclosures used to reduce fugitive emissions from the production furnaces exhibited good containment characteristics when closed, but they failed to contain emissions effectively when opened during product removal/harvesting. The exhaust filtration systems employed for exhausting these ventilated enclosures did not provide promised collection efficiencies for removing engineered nanomaterials from furnace exhaust. The exterior hoods were found to be a challenge for controlling emissions from machining nanocomposites: the downdraft hood effectively contained and removed particles released from the manual cutting process, but using the canopy hood for powered cutting of nanocomposites created 15%-20% higher ultrafine (<500 nm) particle concentrations at the source and at the worker's breathing zone. The microscopy analysis showed that CNTs can only be found at production sources but not at the worker breathing zones during the tasks monitored.

9.
J Occup Environ Hyg ; 12(1): 16-28, 2015.
Article in English | MEDLINE | ID: mdl-24918905

ABSTRACT

Because nanomaterials are thought to be more biologically active than their larger parent compounds, careful control of exposures to nanomaterials is recommended. Field studies were conducted at three sites to develop information about the effectiveness of control measures including process changes, a downflow room, a ventilated enclosure, and an enclosed reactor. Aerosol mass and number concentrations were measured during specific operations with a photometer and an electrical mobility particle sizer to provide concentration measurements across a broad range of sizes (from 5.6 nm to 30 µm). At site A, the dust exposure and during product harvesting was eliminated by implementing a wait time of 30 -min following process completion. And, the dust exposure attributed to process tank cleaning was reduced from 0.7 to 0.2 mg/m3 by operating the available process ventilation during this task. At site B, a ventilated enclosure was used to control dust generated by the manual weigh-out and manipulation of powdered nanomaterials inside of a downflow room. Dust exposures were at room background (under 0.04 mg/m3 and 500 particles/cm3) during these tasks however, manipulations conducted outside of the enclosure were correlated with a transient increase in concentration measured at the source. At site C, a digitally controlled reactor was used to produce aligned carbon nanotubes. This reactor was a closed system and the ventilation functioned as a redundant control measure. Process emissions were well controlled by this system with the exception of increased concentrations measured during the unloading of the product. However, this emission source could be easily controlled through increasing cabinet ventilation. The identification and adoption of effective control technologies is an important first step in reducing the risk associated with worker exposure to engineered nanoparticles. Properly designing and evaluating the effectiveness of these controls is a key component in a comprehensive health and safety program.


Subject(s)
Air Pollutants, Occupational/analysis , Air Pollution, Indoor/prevention & control , Nanostructures/analysis , Occupational Exposure/prevention & control , Ventilation , Aerosols/analysis , Dust , Nanotubes, Carbon/analysis , Ventilation/methods
10.
J Occup Environ Hyg ; 11(10): D164-73, 2014.
Article in English | MEDLINE | ID: mdl-25175285

ABSTRACT

The most commonly reported control used to minimize workplace exposures to nanomaterials is the chemical fume hood. Studies have shown, however, that significant releases of nanoparticles can occur when materials are handled inside fume hoods. This study evaluated the performance of a new commercially available nano fume hood using three different test protocols. Tracer gas, tracer nanoparticle, and nanopowder handling protocols were used to evaluate the hood. A static test procedure using tracer gas (sulfur hexafluoride) and nanoparticles as well as an active test using an operator handling nanoalumina were conducted. A commercially available particle generator was used to produce sodium chloride tracer nanoparticles. Containment effectiveness was evaluated by sampling both in the breathing zone (BZ) of a mannequin and operator as well as across the hood opening. These containment tests were conducted across a range of hood face velocities (60, 80, and 100 ft/min) and with the room ventilation system turned off and on. For the tracer gas and tracer nanoparticle tests, leakage was much more prominent on the left side of the hood (closest to the room supply air diffuser) although some leakage was noted on the right side and in the BZ sample locations. During the tracer gas and tracer nanoparticle tests, leakage was primarily noted when the room air conditioner was on for both the low and medium hood exhaust airflows. When the room air conditioner was turned off, the static tracer gas tests showed good containment across most test conditions. The tracer gas and nanoparticle test results were well correlated showing hood leakage under the same conditions and at the same sample locations. The impact of a room air conditioner was demonstrated with containment being adversely impacted during the use of room air ventilation. The tracer nanoparticle approach is a simple method requiring minimal setup and instrumentation. However, the method requires the reduction in background concentrations to allow for increased sensitivity.


Subject(s)
Air Pollutants, Occupational/analysis , Inhalation Exposure/prevention & control , Metal Nanoparticles/analysis , Occupational Exposure/prevention & control , Air Movements , Air Pollution, Indoor/prevention & control , Equipment Design , Gases/analysis , Humans , Laboratories , Manikins , Nanoparticles , Sulfur Hexafluoride , Ventilation/standards
11.
J Occup Environ Hyg ; 11(10): 680-7, 2014.
Article in English | MEDLINE | ID: mdl-24649880

ABSTRACT

Exposures to diacetyl, a primary ingredient of butter flavoring, have been shown to cause respiratory disease among workers who mix flavorings. This study focused on evaluating ventilation controls designed to reduce emissions from the flavor mixing tanks, the major source of diacetyl in the plants. Five exhaust hood configurations were evaluated in the laboratory: standard hinged lid-opened, standard hinged lid-closed, hinged lid-slotted, dome with 38-mm gap, and dome with 114-mm gap. Tracer gas tests were performed to evaluate quantitative capture efficiency for each hood. A perforated copper coil was used to simulate an area source within the 1.2-meter diameter mixing tank. Capture efficiencies were measured at four hood exhaust flow rates (2.83, 5.66, 11.3, and 17.0 cubic meters per min) and three cross draft velocities (0, 30, and 60 meters per min). All hoods evaluated performed well with capture efficiencies above 90% for most combinations of exhaust volume and cross drafts. The standard hinged lid was the least expensive to manufacture and had the best average capture efficiency (over 99%) in the closed configuration for all exhaust flow rates and cross drafts. The hinged lid-slotted hood had some of the lowest capture efficiencies at the low exhaust flow rates compared to the other hood designs. The standard hinged lid performed well, even in the open position, and it provided a flexible approach to controlling emissions from mixing tanks. The dome hood gave results comparable to the standard hinged lid but it is more expensive to manufacture. The results of the study indicate that emissions from mixing tanks used in the production of flavorings can be controlled using simple inexpensive exhaust hoods.


Subject(s)
Air Pollution, Indoor/prevention & control , Diacetyl/analysis , Equipment Design , Flavoring Agents/analysis , Food-Processing Industry , Occupational Exposure/prevention & control , Ventilation/methods , Air Pollutants, Occupational/analysis
12.
J Occup Environ Hyg ; 11(7): D92-100; quiz D101-3, 2014.
Article in English | MEDLINE | ID: mdl-24568306

ABSTRACT

Investigations of carbon monoxide (CO-related poisonings and deaths on houseboats were conducted by the Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. These investigations measured hazardous CO concentrations on and around houseboats that utilize gasoline-powered generators. Engineering control devices were developed and tested to mitigate this deadly hazard. CO emissions were measured using various sampling techniques which included exhaust emission analyzers, detector tubes, evacuated containers (grab air samples analyzed by a gas chromatograph), and direct-reading CO monitors. CO results on houseboats equipped with gasoline-powered generators without emission controls indicated hazardous CO concentrations exceeding immediately dangerous to life and health (IDLH) levels in potentially occupied areas of the houseboat. Air sample results on houseboats that were equipped with engineering controls to remove the hazard were highly effective and reduced CO levels by over 98% in potentially occupied areas. The engineering control devices used to reduce the hazardous CO emissions from gasoline-powered generators on houseboats were extremely effective at reducing CO concentrations to safe levels in potentially occupied areas on the houseboats and are now beginning to be widely used.


Subject(s)
Air Pollution, Indoor/analysis , Carbon Monoxide Poisoning/prevention & control , Carbon Monoxide/analysis , Housing , Inhalation Exposure/analysis , Ships , Vehicle Emissions/analysis , Air Pollution, Indoor/statistics & numerical data , Engineering , Equipment Design , Gasoline , Humans , Inhalation Exposure/statistics & numerical data , National Institute for Occupational Safety and Health, U.S. , United States , Vehicle Emissions/poisoning
13.
Ann Occup Hyg ; 54(5): 514-31, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20447936

ABSTRACT

Detailed investigations were conducted at a facility that manufactures and processes carbon nanofibers (CNFs). Presented research summarizes the direct-reading monitoring aspects of the study. A mobile aerosol sampling platform, equipped with an aerosol instrument array, was used to characterize emissions at different locations within the facility. Particle number, respirable mass, active surface area, and photoelectric response were monitored with a condensation particle counter (CPC), a photometer, a diffusion charger, and a photoelectric aerosol sensor, respectively. CO and CO(2) were additionally monitored. Combined simultaneous monitoring of these metrics can be utilized to determine source and relative contribution of airborne particles (CNFs and others) within a workplace. Elevated particle number concentrations, up to 1.15 x 10(6) cm(-3), were found within the facility but were not due to CNFs. Ultrafine particle emissions, released during thermal treatment of CNFs, were primarily responsible. In contrast, transient increases in respirable particle mass concentration, with a maximum of 1.1 mg m(-3), were due to CNF release through uncontrolled transfer and bagging. Of the applied metrics, our findings suggest that particle mass was probably the most useful and practical metric for monitoring CNF emissions in this facility. Through chemical means, CNFs may be selectively distinguished from other workplace contaminants (Birch et al., in preparation), and for direct-reading monitoring applications, the photometer was found to provide a reasonable estimate of respirable CNF mass concentration. Particle size distribution measurements were conducted with an electrical low-pressure impactor and a fast particle size spectrometer. Results suggest that the dominant CNF mode by particle number lies between 200 and 250 nm for both aerodynamic and mobility equivalent diameters. Significant emissions of CO were also evident in this facility. Exposure control recommendations were described for processes as required.


Subject(s)
Aerosols/analysis , Air Pollutants, Occupational/analysis , Carbon/analysis , Environmental Monitoring/methods , Nanofibers/analysis , Aerosols/chemistry , Air Pollutants, Occupational/chemistry , Carbon/chemistry , Carbon Dioxide/analysis , Carbon Monoxide/analysis , Environmental Monitoring/instrumentation , Humans , Inhalation Exposure/analysis , Inhalation Exposure/prevention & control , Inhalation Exposure/statistics & numerical data , Nanofibers/chemistry , Nanofibers/standards , Nanotechnology/methods , Occupational Exposure/analysis , Occupational Exposure/prevention & control , Occupational Exposure/statistics & numerical data , Particle Size , Particulate Matter/analysis , Particulate Matter/chemistry , Time Factors , Workplace/standards
14.
J Occup Environ Med ; 52(2): 207-13, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20134344

ABSTRACT

OBJECTIVES: To determine the cause of eye and respiratory irritation symptoms among lifeguards at an indoor waterpark. METHODS: Investigators 1) performed environmental sampling for chloramine, endotoxin, and microbials; 2) administered symptom questionnaires; 3) reviewed ventilation system designs; and 4) reviewed water chemistry. RESULTS: Airborne trichloramine concentrations were found at levels reported to cause irritation symptoms in other studies. Some endotoxin concentrations were found at levels associated with cough and fever in previous studies. Exposed lifeguards were significantly more likely to report work-related irritation symptoms than unexposed individuals. The ventilation system may not have provided sufficient air movement and distribution to adequately capture and remove air contaminants at deck level. No water microbes were detected, and water chemistry met state standards. CONCLUSIONS: Indoor waterparks need to control water chemistry and ensure adequate air movement and distribution to control air contaminants and reduce health symptoms.


Subject(s)
Eye Diseases/etiology , Health Resorts , Occupational Exposure/adverse effects , Respiratory Tract Diseases/etiology , Swimming Pools , Adolescent , Adult , Air Pollutants, Occupational/adverse effects , Air Pollutants, Occupational/analysis , Chloramines/adverse effects , Chloramines/analysis , Endotoxins/adverse effects , Endotoxins/analysis , Environmental Microbiology , Eye Diseases/epidemiology , Female , Humans , Humidity , Male , Middle Aged , Occupational Diseases/epidemiology , Occupational Diseases/etiology , Occupational Exposure/analysis , Prevalence , Respiratory Tract Diseases/epidemiology , Temperature , Young Adult
15.
Inhal Toxicol ; 21(1): 55-61, 2009 Jan.
Article in English | MEDLINE | ID: mdl-18946764

ABSTRACT

Exposure to the range of combustion products from wildland fires has been demonstrated to cause respiratory irritation and decreased lung function among firefighters. The measurement of carbon monoxide (CO) has been previously shown to be highly correlated with the range of contaminants found in wildland fires. In this article, we assess the feasibility of using a simple, noninvasive biological test to assess exposure to CO for a group of wildland firefighters. Measurements of CO exposure were collected using personal monitors as well as in exhaled breath for wildland firefighters who conducted prescribed burns in February-March 2004. Overall, the CO concentrations measured in this study group were low with a shift mean of 1.87 ppm. Correspondingly, the cross-shift difference in carboxyhemoglobin as estimated from exhaled breath CO levels was also low (median increase =+0.2% carboxyhemoglobin). The use of exhaled breath measurements for CO has limitations in characterizing exposures within this worker population.


Subject(s)
Breath Tests/methods , Carbon Monoxide/analysis , Fires , Occupational Exposure/prevention & control , Breath Tests/instrumentation , Carboxyhemoglobin/analysis , Exhalation , Forestry , Humans , Inhalation Exposure/adverse effects , Monitoring, Ambulatory/instrumentation , Monitoring, Ambulatory/methods , Regression Analysis , Smoke/analysis , Smoke Inhalation Injury/diagnosis , Smoke Inhalation Injury/prevention & control
17.
Environ Res ; 106(3): 401-9, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18199434

ABSTRACT

BACKGROUND: Flooding in the greater New Orleans (GNO) area after the hurricanes caused extensive mold growth in homes resulting in public health concerns. OBJECTIVES: We conducted an environmental assessment of homes to determine the extent and type of microbial growth. METHODS: We randomly selected 112 homes, stratified by water damage, and then visually assessed mold growth. Air samples from a subset of 20 homes were analyzed for culturable fungi, fungal spores, and markers of mold ((1-->3, 1-->6)-beta-D-glucans) and bacteria (endotoxin). RESULTS: Visible mold growth occurred in 49 (44%) homes; 18 (16%) homes had >50% mold coverage. Flood levels were >6 ft at 20 (19%), 3-6 ft at 20 (19%), and <3 ft at 28 (26%) homes out of 107; no flooding at 39 (36%) homes. The residents spent an average of 18 h (range: 1-84) doing heavy cleaning and of those, 22 (38%) reported using an N-95 or other respirator. Visible mold growth was significantly associated with flood height 3 ft and the predominant fungi indoors were Aspergillus and Penicillium species, which were in higher concentrations in homes with a flood level 3 ft. Geometric mean (GM) levels of endotoxin were as high as 40.2 EU/m(3), while GM glucan levels were as high as 3.5 microg/m(3) even when flooding was 3 ft. CONCLUSIONS: Based on our observations of visible mold, we estimated that elevated mold growth was present in 194,000 (44%) homes in the GNO area and 70,000 (16%) homes had heavy mold growth. Concentrations of endotoxin and glucans exceeded those previously associated with health effects. With such high levels of microbial growth following flooding, potentially harmful inhalation exposures can be present for persons entering or cleaning affected homes. Persons exposed to water-damaged homes should follow the CDC recommendations developed following the 2005 hurricanes for appropriate respiratory precautions.


Subject(s)
Air Microbiology , Air Pollutants/analysis , Disasters , Fungi/growth & development , Adolescent , Adult , Aged , Aged, 80 and over , Endotoxins/analysis , Female , Humans , Louisiana , Male , Masks , Middle Aged , Statistics, Nonparametric , Surveys and Questionnaires , Urban Population
18.
Am J Prev Med ; 32(4): 340-6, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17383566

ABSTRACT

BACKGROUND: During August-September 2004, four major hurricanes hit Florida, resulting in widespread power outages affecting several million households. Carbon monoxide (CO) poisonings during this period were investigated to identify ways to prevent future poisoning. METHODS: Medical records from ten hospitals (two with hyperbaric oxygen chambers) were reviewed to identify individuals diagnosed with unintentional CO poisoning between August 13 and October 15, 2004. Multiple attempts were made to interview one person from each nonfatal incident. Medical examiner records and reports of investigations conducted by the U.S. Consumer Product Safety Commission of six fatal poisonings from five additional incidents were also reviewed. RESULTS: A total of 167 people treated for nonfatal CO poisoning were identified, representing 51 incidents. A portable, gasoline-powered generator was implicated in nearly all nonfatal incidents and in all fatal poisonings. Generators were most often located outdoors, followed by inside the garage, and inside the home. Telephone interviews with representatives of 35 (69%) incidents revealed that concerns about theft or exhaust most often influenced the choice of location. Twenty-six (74%) households did not own a generator before the hurricanes, and 86% did not have a CO detector at the time of the poisoning. Twenty-one (67%) households reported reading or hearing CO education messages before the incident. CONCLUSIONS: Although exposure to public education messages may have encouraged more appropriate use of generators, a substantial number of people were poisoned even when the devices were operated outdoors. Additional educational efforts and engineering solutions that reduce CO emission from generators should be the focus of public health activities.


Subject(s)
Carbon Monoxide Poisoning/epidemiology , Disasters , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Florida/epidemiology , Humans , Infant , Interviews as Topic , Male , Medical Audit , Middle Aged
19.
Appl Environ Microbiol ; 73(5): 1630-4, 2007 Mar.
Article in English | MEDLINE | ID: mdl-17209066

ABSTRACT

In August and September 2005, Hurricanes Katrina and Rita caused breeches in the New Orleans, LA, levee system, resulting in catastrophic flooding. The city remained flooded for several weeks, leading to extraordinary mold growth in homes. To characterize the potential risks of mold exposures, we measured airborne molds and markers of molds and bacteria in New Orleans area homes. In October 2005, we collected air samples from 5 mildly water-damaged houses, 15 moderately to heavily water-damaged houses, and 11 outdoor locations. The air filters were analyzed for culturable fungi, spores, (1-->3,1-->6)-beta-D-glucans, and endotoxins. Culturable fungi were significantly higher in the moderately/heavily water-damaged houses (geometric mean=67,000 CFU/m3) than in the mildly water-damaged houses (geometric mean=3,700 CFU/m3) (P=0.02). The predominant molds found were Aspergillus niger, Penicillium spp., Trichoderma, and Paecilomyces. The indoor and outdoor geometric means for endotoxins were 22.3 endotoxin units (EU)/m3 and 10.5 EU/m3, respectively, and for (1-->3,1-->6)-beta-D-glucans were 1.7 microg/m3 and 0.9 microg/m3, respectively. In the moderately/heavily water-damaged houses, the geometric means were 31.3 EU/m3 for endotoxins and 1.8 microg/m3 for (1-->3,1-->6)-beta-D-glucans. Molds, endotoxins, and fungal glucans were detected in the environment after Hurricanes Katrina and Rita in New Orleans at concentrations that have been associated with health effects. The species and concentrations were different from those previously reported for non-water-damaged buildings in the southeastern United States.


Subject(s)
Air Microbiology , Air Pollution, Indoor/analysis , Disasters , Fungi/classification , Fungi/isolation & purification , Housing , Aspergillus niger/isolation & purification , Endotoxins/analysis , Environmental Monitoring , Fungi/physiology , Glucans/analysis , Louisiana , Paecilomyces/isolation & purification , Penicillium/isolation & purification , Spores, Fungal/isolation & purification , Trichoderma/isolation & purification
20.
Arch Environ Occup Health ; 60(1): 40-3, 2005.
Article in English | MEDLINE | ID: mdl-16961007

ABSTRACT

High particulate exposures have been demonstrated to decrease lung function among firefighters. In this article, the authors demonstrated the feasibility of using small real-time particle sensors to inform wildland firefighters so they may make informed decisions on the use of personal respiratory protection. Using 1 mg/m3 as an indicator point for use of appropriately designed respiratory protection, such sensors could help prevent 16% to 74% of particulate exposure during prescribed burns when firefighters assess exposure as low or medium. Adherence to such a guideline for the use of respiratory protection would involve its deployment during 3% to 22% of individual 8-hour shifts. In addition, data-logging sensors would provide a valuable tool for tracking exposure to particulates among wildland firefighters for occupational health monitoring.


Subject(s)
Dust , Environmental Monitoring/instrumentation , Fires , Occupational Diseases/prevention & control , Occupational Exposure/prevention & control , Trees , Adult , Feasibility Studies , Humans , Risk Assessment
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