ABSTRACT
A large cardiac rhabdomyoma was discovered before delivery in a neonate, whose outcome was fatal. The baby and her mother had both cutaneous lesions suggestive of tuberous sclerosis, and the mother's sister had died from Von Hippel Lindau disease. The association of a cardiac rhabdomyoma and a tuberous sclerosis in the same patient is not uncommon, but the existence of Von Hippel Lindau disease in a member of the same family seems to be exceptional.
Subject(s)
Angiomatosis/complications , Heart Neoplasms/complications , Rhabdomyoma/complications , Tuberous Sclerosis/complications , von Hippel-Lindau Disease/complications , Female , Heart Neoplasms/genetics , Humans , Infant, Newborn , Rhabdomyoma/geneticsSubject(s)
Appendix/transplantation , Ureter/surgery , Humans , Infant , Male , Transplantation, Autologous , Ureteral Calculi/surgeryABSTRACT
The association of a diaphragmatic hernia and a pulmonary sequestration is known, though very rare. The authors present one singular observation because it were involved in aplasia of the homolateral pillar and a digestive duplication. They insist about the gravity of the reflux inherent to the malformation; they suggest its differed cure in spite of nutritional difficulties. Pathogenic considerations are advanced on that malformative complexe which is combined with the broncho-pulmonaries malformations of the foregut. It seems a direct proof of the theory of "the accessory lung". Finally, is underlined the gravity of the aplasia of the diaphragmatic leaf extensive to the pillar.
Subject(s)
Abnormalities, Multiple/surgery , Bronchopulmonary Sequestration/complications , Diaphragm/abnormalities , Digestive System Abnormalities , Hernias, Diaphragmatic, Congenital , Abnormalities, Multiple/pathology , Bronchopulmonary Sequestration/pathology , Bronchopulmonary Sequestration/surgery , Diaphragm/surgery , Gastroesophageal Reflux/surgery , Hernia, Diaphragmatic/surgery , Humans , Infant , Infant, Newborn , MaleABSTRACT
Severe iodine-induced hypothyroidism was recently diagnosed in several neonates raising the responsibility of the iodine antiseptic agents routinely used in these patients. Postnatal iodine overload due to cutaneous application of these agents (povidone iodine and fluorescinated alcoholic-iodine solution) was studied in 5 patients. Thyroid function studies were performed in iodine-overload neonates and in control neonates with comparable gestional age. Results indicated strong evidence of cutaneous absorption of iodine from the antiseptic agents used, leading to hypothyroidism in 12 of them. The frequency and the severity of thyroid dysfunction was closely related to the degree of prematurity. Full recovery was observed in all cases after withdrawal of the iodine-containing agents. It is therefore recommended to avoid any postnatal use of iodine preparations in neonates, mainly in preterm infants, and to use iodine antiseptic agents with great caution, when necessary during the neonatal period.
Subject(s)
Anti-Infective Agents, Local/adverse effects , Benzalkonium Compounds/adverse effects , Hypothyroidism/chemically induced , Infant, Newborn, Diseases/chemically induced , Iodine/adverse effects , Female , Gestational Age , Humans , Infant , Infant, Newborn , Infant, Premature , Male , Povidone-Iodine/adverse effects , Retrospective Studies , Thyroid Function TestsSubject(s)
Thrombosis/complications , Thrombosis/diagnosis , Umbilical Arteries , Acute Disease , Apgar Score , Bradycardia/etiology , Female , Fetal Distress/etiology , Hematoma/etiology , Humans , Infant, Newborn , Male , Morbidity , Obstetric Labor, Premature/complications , Oxygen Inhalation Therapy , Pregnancy , Prognosis , Rare Diseases , Respiratory Insufficiency/etiology , Risk Factors , Thrombosis/epidemiology , Thrombosis/therapy , Umbilical Cord/blood supply , Umbilical Cord/embryologyABSTRACT
Anatomical and clinical observations are described in a case of carbon monoxide poisoning which caused the death of the baby rapidly. The anatomical lesions are comparable to those observed in 8 other cases reported in the literature. The physiopathological mechanism involved is discussed in relation to previously reported clinical, toxicological, and experimental data.
Subject(s)
Brain/pathology , Carbon Monoxide Poisoning/pathology , Fetal Diseases/chemically induced , Fetus/drug effects , Adult , Carbon Monoxide/blood , Female , Fetal Diseases/pathology , Humans , Infant, Newborn , Male , Maternal-Fetal Exchange , PregnancySubject(s)
Intestinal Obstruction/congenital , Bacteremia/diagnosis , Bacteremia/etiology , Bacteremia/therapy , Bacterial Infections/diagnosis , Bacterial Infections/etiology , Bacterial Infections/therapy , Cooperative Behavior , Diagnosis, Differential , Humans , Infant, Newborn , Intensive Care Units, Neonatal , Intestinal Obstruction/complications , Intestinal Obstruction/diagnosis , Intestinal Obstruction/therapy , Patient Care Team , Prognosis , Risk FactorsABSTRACT
Bronchiolitis in newborns is a frequent infection, usually with a good prognosis. But there are also more severe forms, better known now, endangering the vital prognosis. The authors report the experience of an infant intensive care unit, where 13 cases of severe bronchiolitis were treated. After considering the etiological circumstances, they envisage the physio-pathological problems. Clinical and paraclinical signs are described. The authors particularly insist on the treatment of severe bronchiolitis using respiratory reanimation. In many cases, assisted ventilation with tracheal intubation helps to get over the worst part. Treatment of severe bronchiolitis remains today essentially symptomatic, but the practice of the appropriate treatment enables in most cases to cure the disease.