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1.
J Emerg Med ; 66(4): e477-e482, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38433037

ABSTRACT

BACKGROUND: Medical equipment can become scarce in disaster scenarios. Prior work has reported that four sheep could be ventilated together on a single ventilator. Others found that this maneuver is possible when needed, but no one has yet investigated whether cross-contamination occurs in co-ventilated individuals. OBJECTIVE: Our goal was to investigate whether an infection could spread between co-ventilated individuals. METHODS: Four 2-L anesthesia bags were connected to a sterilized ventilator circuit that used heat and moisture exchange filters and bacterial and viral filters, as would be expected in this dire scenario. Serratia marcescens was inoculated into "lung" no. 1. After running for 24 h, each lung and three additional points in the circuit were cultured to see whether S. marcescens had spread. These cultures were examined at 24 and 48 h to assess for cross-contamination. This entire procedure was performed three times. RESULTS: S. marcescens was not found in lung no. 2, 3, or 4 or the three additional sites on the expiratory limb at 24 and 48 h in all three trials. CONCLUSIONS: Cross-contamination does not occur within 24 h using the described ventilator circuit configuration.


Subject(s)
Equipment Contamination , Ventilators, Mechanical , Humans , Bacteria , Filtration , Lung , Respiration, Artificial
2.
Emerg Med J ; 38(3): 220-223, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33277345

ABSTRACT

BACKGROUND: Disasters have the potential to cause critical shortages of life-saving equipment. It has been postulated that during patient surge, multiple individuals could be maintained on a single ventilator. This was supported by a previous trial that showed one ventilator could support four sheep. The goal of our study is to investigate if cross contamination of pathological agents occurs between individuals on a shared ventilator with strategically placed antimicrobial filters. METHODS: A multipatient ventilator circuit was assembled using four sterile, parallel standard tubing circuits attached to four 2 L anaesthesia bags, each representing a simulated patient. Each 'patient' was attached to a Heat and Moisture Exchange filter. An additional bacterial/viral filter was attached to each expiratory limb. 'Patient-Lung' number 1 was inoculated with an isolate of Serratia marcescens, and the circuit was run for 24 hours. Each 'lung' and three points in the expiratory limb tubing were washed with broth and cultured. All cultures were incubated for 48 hours with subcultures performed at 24 hours. RESULTS: Washed cultures of patient 2, 3 and 4 failed to demonstrate growth of S. marcescens. Cultures of the distal expiratory tubing, expiratory limb connector and expiratory limb prefilter tubing yielded no growth of S. marcescens at 24 or 48 hours. CONCLUSION: Based on this circuit configuration, it is plausible to maintain four individuals on a single ventilator for 24 hours without fear of cross contamination.


Subject(s)
Cross Infection/transmission , Equipment Contamination , Filtration/instrumentation , Ventilators, Mechanical , Equipment Design , Humans
3.
RN ; 72(8): 36, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19743589
4.
RN ; 71(6): 19, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18686915
5.
RN ; 71(4): 21, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18524351
6.
RN ; 71(2): 22, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18386440

Subject(s)
Contracts , Nursing , Travel , Humans
7.
Resuscitation ; 77(1): 121-6, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18164798

ABSTRACT

OBJECTIVE: Recent manmade and natural disasters have focused attention on the need to provide care to large groups of patients. Clinicians, ethicists, and public health officials have been particularly concerned about mechanical ventilator surge capacity and have suggested stock-piling ventilators, rationing, and providing manual ventilation. These possible solutions are complex and variously limited by legal, monetary, physical, and human capital restraints. We conducted a study to determine if a single mechanical ventilator can adequately ventilate four adult-human-sized sheep for 12h. METHODS: We utilized a four-limbed ventilator circuit connected in parallel. Four 70-kg sheep were intubated, sedated, administered neuromuscular blockade and placed on a single ventilator for 12h. The initial ventilator settings were: synchronized intermittent mandatory ventilation with 100% oxygen at 16 breaths/min and tidal volume of 6 ml/kg combined sheep weight. Arterial blood gas, heart rate, and mean arterial pressure measurements were obtained from all four sheep at time zero and at pre-determined times over the course of 12h. RESULTS: The ventilator and modified circuit successfully oxygenated and ventilated the four sheep for 12h. All sheep remained hemodynamically stable. CONCLUSION: It is possible to ventilate four adult-human-sized sheep on a single ventilator for at least 12h. This technique has the potential to improve disaster preparedness by expanding local ventilator surge capacity until emergency supplies can be delivered from central stockpiles. Further research should be conducted on ventilating individuals with different lung compliances and on potential microbial cross-contamination.


Subject(s)
Disasters , Respiratory Insufficiency/therapy , Ventilators, Mechanical/supply & distribution , Animals , Equipment Design , Female , Sheep, Domestic
11.
RN ; 69(9): 58, 2006 Sep.
Article in English | MEDLINE | ID: mdl-17017326
12.
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