ABSTRACT
Gagea genus, which is native to the Mediterranean and Black Sea regions, has attracted significant attention due to its biodiversity and potential health benefits. In this study, the biochemical composition and biological activities of methanol extracts from various parts of G. taurica were investigated, along with their anatomical and morphological characteristics. The best antimicrobial activity was found to be MeOH extracts of corm and leaf against several Candida strains with MIC=640â µg/mL. The highest level of phenolics together with significant results of antioxidant activities were observed in flowers extracts. The α-amylase inhibition assay results showed that the highest inhibition percentage was observed with acarbose (59 %), followed by leaf extract (43 %). Leaf exhibited the most effective inhibitory activity in AChE inhibition assay, whereas flower demonstrated the most significant inhibitory activity in BChE inhibition assay. Hesperidin was found as 1621.0001 ng/ml value in flower extract and 283.9339â ng/ml value leaf.
Subject(s)
Liliaceae , Biodiversity , Biological Assay , Black Sea , Plant Extracts/pharmacologyABSTRACT
Ferula tingitana L. is a high perennial plant and its leaf is an alternate arrangement and yellow, and its flowers are unisexual like other Apiaceae. It has been used as a spice and for various medicinal purposes in the Mediterranean region. The paper reports antidiabetic, antimicrobial, anticholinesterase, antioxidant, and genotoxic activities of leaves, flowers, stems, and fruits methanol extracts of F. tingitana. Also, quantitative determination of some secondary metabolites was also analyzed by LC-MS/MS. Moreover, chemical composition of essential oils was analyzed. Consequently, anatomical, and morphological properties of plant were investigated. Germacrene D (23.6%), 1,3,5-trimethylbenzene (18.4%), and α-pinene (50.0%) were found as the main compounds in flower, leaf, and stem oils, respectively. The cortex in stem, pedicel, and fruit is characterized by angular collenchyma cells and a distinct cambium layer. 6 compounds (quinic acid, fumaric acid, keracyanin chloride, cyanidin-3-O-glucoside, chlorogenic acid, hesperidin) were observed in samples. Leaf extract showed anticholinesterase activity. Leaf and flower extracts showed the highest % inhibition value on ABTS·+ and DPPHâ¢. Leaf extract has the strongest antioxidant effect because it is rich in total phenolic contents. All extracts of F. tingitana were found generally effective against C. albicans. Stem extract was found effective against E. coli and flower extract was found more effective against S. enterica and C. albicans. Bacterial genotoxicity results showed that extracts did not have genotoxic activity on tester strains S. typhimurium and E. coli WP2uvrA. Thus, it revealed that extracts were genotoxic-ally safe at applied concentrations up to 3 mg/plate.
ABSTRACT
ETHNOPHARMACOLOGICAL RELEVANCE: Garlic and its wild relatives have a long tradition of use world-wide dating back to the early ages as food and medicine. This exceptional group deserves to be taken into consideration to rethink its potential health effects in light of its cultural and historical background, as well as ethnobotanical practices. AIM OF THE STUDY: Garlic, onion, and other related vegetables have been indispensable for Turkish daily life. This review focuses on the wild, as well as cultivated, Allium species from the broad historical perspective of Turkish culture. Its goal is also analyze how food and medicine have been perceived as closely connected entities in a specific cultural sphere. METHODS: A comprehensive literature survey was conducted on these species by referencing scientific databases such as Google Scholar, Science Direct, PubMed, Elsevier E-Book, Scopus, ISI-Web of Science, and E book Central (Ebrary). RESULTS: The integration of historical and ethnobotanical data have enabled us to understand the unique position of Alliums in a specific human geography. Garlic and onions have been used in this region as food and for medicinal purposes for thousands of years. The perceived health benefits of consuming garlic and onions are well documented in the literature. There are more than 200 Allium species naturally distributed in Turkey, and around 30 of those have been widely used for various purposes by local people as a vegetable, spice, condiment, and medicine. CONCLUSIONS: The desire for good health and wellness has been traced across many cultures throughout history. Healthy foods like garlic were and will be a critical component of maintaining good health.
Subject(s)
Garlic , Onions , Animals , Ethnopharmacology , Humans , Phytotherapy , TurkeyABSTRACT
Allium ekimianum is described here as a new species. This taxon belongs to the genus Allium section Allium and grows in Elazig Province (East Anatolia, Turkey). It is a narrowly distributed species and morphologically most similar to Allium asperiflorum and Allium sintenisii, and Allium erzincanicum but it is clearly differentiated due to the curved stem, smooth pedicel surfaces, bracteole arrangements at pedicel bases, tepal lengths and surfaces. In this study, a comprehensive description, distribution map of Allium ekimianum, identification key, and detailed illustrations are provided for Allium ekimianum and related taxa.
