ABSTRACT
OBJECTIVE: To evaluate the incidence of laryngeal papillomatosis (LP) and LP recurrence in adults and to determine the risk factors for the development of LP recurrence in adults in Moscow. To solve the tasks set, a survey of patients carried out, including the collection of complaints and anamnesis, a standard examination of the ENT organs, an assessment of the condition of the larynx, and a histological examination. MATERIAL AND METHODS: We conducted a retrospective analysis of the case histories of 299 patients with LP observed and treated at the Sverzhevsky Research and Clinical Institute of Otorhinolaryngology in the period 2010-2020. RESULTS: On average, over the entire study period, the prevalence of PG was 17.80%. It was found that out of 299 patients, 69.6% (n=208) had a relapse of LP. Papilloma of the larynx were more often localized in the glottis. 275 (92%) patients had a widespread form of LP. LP recurrences were significantly more common in women and in patients with an existing cicatricle process in the larynx. The relapse rate was higher in non-smokers (73.5% vs 47.8%; p<0.001). Although the recurrence rate was higher in patients with non-voice occupations (70.6% vs. 52.9%), there was no statistically significant association between relapses and the vocal professions (p=0.125). CONCLUSION: As a result of the study, a number of risk factors for laryngeal papillomatosis recurrent have been identified, and their study should be continued.
Subject(s)
Laryngeal Neoplasms , Papilloma , Humans , Moscow/epidemiology , Male , Female , Papilloma/epidemiology , Laryngeal Neoplasms/epidemiology , Laryngeal Neoplasms/pathology , Adult , Retrospective Studies , Middle Aged , Risk Factors , Incidence , Prevalence , Neoplasm Recurrence, Local/epidemiologyABSTRACT
The literature review describes the experience of using the biofeedback method in the treatment of dysphonia of various etiologies. Indications for the use of this method and its effectiveness in a certain contingent of patients are discussed.
Subject(s)
Dysphonia , Larynx , Humans , Biofeedback, Psychology , Dysphonia/diagnosis , Dysphonia/therapyABSTRACT
The article deals with optimization of treatment policy for singers with chronic catarrhal laryngitis. The survey sample is 51 singers with chronic catarrhal laryngitis of the age from 29 to 54 and the length of time worked from 8 to 22 years. The following methods are used: anamnesis, microbiological investigation, voice evaluation according to Visual Analog Scale (VAS), microlaryngoscopy, videolaryngostroboscopy, voice acoustic analysis (MDVP Kay Pentax system), statistical processing of results. It is shown that the cause of chronic catarrhal laryngitis in professional singers is non-bacterial irritants that provoke the appearance of an inflammatory process in the larynx, as well as uncontrolled use of drugs that irritate and dry out the mucous membrane and imperfect vocal technique. Pathogenic flora as an etiologic factor in the occurrence of laryngitis does not play an important role. A comprehensive treatment scheme for chronic catarrhal laryngitis using inhalation therapy and drugs that improve trophic processes in the laryngeal mucosa, which allows to increase the effectiveness of treatment and achieve stable remission of the disease, is suggested.
Subject(s)
Laryngitis , Larynx , Singing , Voice Disorders , Adolescent , Adult , Child , Chronic Disease , Humans , Laryngitis/diagnosis , Laryngitis/drug therapy , Laryngitis/etiology , Laryngoscopy , Young AdultABSTRACT
Inhalation therapy is a highly effective method of local anti-inflammatory therapy in combined treatment of anti-inflammatory laryngeal diseases. Schemes of inhalation therapy in different laryngeal diseases are presented basing on the experience with examination and treatment of 140 patients.
Subject(s)
Laryngitis/therapy , Respiratory Therapy/methods , Acetylcysteine/administration & dosage , Administration, Inhalation , Adolescent , Adult , Anti-Bacterial Agents/administration & dosage , Benzalkonium Compounds/administration & dosage , Chymotrypsin/administration & dosage , Dexamethasone/administration & dosage , Drug Administration Schedule , Drug Combinations , Expectorants/administration & dosage , Female , Follow-Up Studies , Glucocorticoids/administration & dosage , Humans , Male , Middle Aged , Mineral Waters/administration & dosage , Treatment Outcome , Young AdultABSTRACT
An experimental model of upper respiratory passages has been developed to be used for the choice of parameters of inhalation therapy for inflammatory processes in the larynx and evaluation of its efficiency. The model was employed to characterize "inhalation accessibility" of different segments of the upper respiratory passages and to determine the amount of a medicinal product to be delivered to the affected zone per unit time. Optimal parameters of the inhalation procedure have been derived.
Subject(s)
Aerosols , Laryngeal Diseases/therapy , Respiratory Tract Infections/therapy , Administration, Inhalation , HumansSubject(s)
Anti-Infective Agents, Local/therapeutic use , Benzalkonium Compounds/therapeutic use , Tonsillitis/therapy , Adult , Bacterial Infections/microbiology , Chronic Disease , Female , Humans , Male , Middle Aged , Mucous Membrane/microbiology , Therapeutic Irrigation , Tonsillitis/drug therapy , Tonsillitis/microbiology , Treatment OutcomeABSTRACT
The authors consider the problems of effective general and local antibiotic therapy regarding most frequently occurring now causative agents and doses of antibacterial drugs. Combined use of antibacterial drugs and immunostimulators is analysed as antibacterial drugs deteriorate nonspecific immunity.