ABSTRACT
We report on partial dup(22q), growth deficiency, and the facioauriculovertebral sequence including hemifacial microsomia, cleft lip and palate, preauricular tags, and hearing loss in one patient. No endocrine or systemic cause for growth deficiency was identified. The case illustrates applicability of chromosome analysis in syndrome-associated growth failure, and a previously unreported associated chromosome abnormality.
Subject(s)
Chromosome Aberrations , Chromosomes, Human, Pair 22/genetics , Facial Asymmetry/genetics , Abnormalities, Multiple/genetics , Child, Preschool , Cleft Lip/genetics , Cleft Palate/genetics , Ear, External/abnormalities , Growth Disorders/genetics , Hearing Loss/genetics , Humans , MaleABSTRACT
Children with cleft lip and palate require interdisciplinary team care from infancy through adolescence. An understanding of developmental stages allows the cleft palate team to adapt and integrate its services into the rapidly changing life of the child. This article discusses the maturational, developmental stages of childhood and the services the child with cleft lip and palate and the child's family deserve through each stage. Health care providers in all settings may continue to provide appropriate care for all patients with cleft lip and palate, despite the challenges of a changing health care environment, by emphasizing the needs of the child in all developmental stages.
